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Acromegaly manageme...
Acromegaly management in the nordic countries : a Delphi consensus survey
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- Arlien-Søborg, Mai C. (författare)
- Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark,Aarhus Univ Hosp, Denmark
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- Dal, Jakob (författare)
- Department of Endocrinology, Aalborg University Hospital, Aarhus, Denmark; Steno Diabetes Center North Jutland, Aalborg, Denmark,Aalborg Univ Hosp, Denmark; Steno Diabet Ctr North Jutland, Denmark
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- Heck, Ansgar (författare)
- Oslo University Hospital, Oslo, Norway,Oslo Univ Hosp, Norway
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visa fler...
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- Stochholm, Kirstine (författare)
- Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark,Aarhus Univ Hosp, Denmark
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- Husted, Eigil (författare)
- Department of Endocrinology, Aalborg University Hospital, Aarhus, Denmark,Aalborg Univ Hosp, Denmark
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- Feltoft, Claus Larsen (författare)
- Copenhagen University Hospital—Herlev and Gentofte, Kobenhavn, Denmark,Copenhagen Univ Hosp Herlev & Gentofte, Denmark
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- Rasmussen, Åse Krogh (författare)
- Copenhagen University Hospital, Kobenhavn, Denmark,Copenhagen Univ Hosp, Denmark
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- Feldt-Rasmussen, Ulla (författare)
- Copenhagen University Hospital, Kobenhavn, Denmark,Copenhagen Univ Hosp, Denmark
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- Andreassen, Mikkel (författare)
- Copenhagen University Hospital, Kobenhavn, Denmark,Copenhagen Univ Hosp, Denmark
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- Klose, Marianne Christina (författare)
- Copenhagen University Hospital, Kobenhavn, Denmark,Copenhagen Univ Hosp, Denmark
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- Nielsen, Torben Leo (författare)
- Odense University Hospital, Odense, Denmark,Odense Univ Hosp, Denmark
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- Andersen, Marianne Skovsager (författare)
- Odense University Hospital, Odense, Denmark,Odense Univ Hosp, Denmark
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- Christensen, Louise Lehmann (författare)
- Odense University Hospital, Odense, Denmark,Odense Univ Hosp, Denmark
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- Krogh, Jesper (författare)
- Copenhagen University Hospital, Kobenhavn, Denmark,Copenhagen Univ Hosp, Denmark
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- Jarlov, Anne (författare)
- Copenhagen University Hospital, Kobenhavn, Denmark,Copenhagen Univ Hosp, Denmark
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- Bollerslev, Jens (författare)
- Oslo University Hospital, Oslo, Norway,Oslo Univ Hosp, Norway
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- Nermoen, Ingrid (författare)
- Akershus University Hospital, lørenskog, Norway,Akershus Univ Hosp, Norway
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- Oksnes, Marianne (författare)
- Haukeland University Hospital, Bergen, Norway,Haukeland Hosp, Norway
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- Dahlqvist, Per (författare)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin,Norrlands University Hospital, Umeå, Sweden,Umea Univ, Sweden; Norrlands Univ Hosp, Sweden
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- Olsson, Tommy (författare)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin,Norrlands University Hospital, Umeå, Sweden,Umea Univ, Sweden; Norrlands Univ Hosp, Sweden
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- Berinder, Katarina (författare)
- Karolinska University Hospital, Sweden,Karolinska Univ Hosp, Sweden
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- Hoybye, Charlotte (författare)
- Karolinska University Hospital, Sweden,Karolinska Univ Hosp, Sweden
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- Petersson, Maria (författare)
- Karolinska University Hospital, Sweden,Karolinska Univ Hosp, Sweden
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- Akerman, Anna-karin (författare)
- School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Sweden; Department of Medicine, Örebro University Hospital, Örebro, Sweden,Orebro Univ, Sweden
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- Wahlberg, Jeanette (författare)
- Department of Medicine, Örebro University Hospital, Örebro, Sweden,Orebro Univ Hosp, Sweden
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- Ekman, Bertil (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Medicinkliniken ViN,Region Östergötland, Endokrinmedicinska kliniken,Department of Endocrinology and the Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
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- Engstrom, Britt Eden (författare)
- Uppsala University Hospital, Uppsala, Sweden,Uppsala Univ Hosp, Sweden
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- Johannsson, Gudmundur (författare)
- Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden; Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg & Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Sweden; Univ Gothenburg, Sweden; Sahlgrens Univ Hosp, Sweden
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- Ragnarsson, Oskar (författare)
- Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden,Sahlgrens Univ Hosp, Sweden
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- Olsson, Daniel (författare)
- Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden; Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg & Sahlgrenska University Hospital, Gothenburg, Sweden; Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden,Sahlgrens Univ Hosp, Sweden; Univ Gothenburg, Sweden; AstraZeneca, Sweden
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- Sigurjónsdóttir, Helga Ágústa (författare)
- The National University Hospital of Iceland, Gothenburg, Iceland; School of Medicine, University of Iceland, Reykjavik, Iceland,Natl Univ Hosp Iceland, Iceland; Univ Iceland, Iceland
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- Fougner, Stine Lyngvi (författare)
- Department of Endocrinology, St. Olavs hospital, Trondheim University Hospital, Trondheim, Norway; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway,Trondheim Reg & Univ Hosp, Norway; Norwegian Univ Sci & Technol NTNU, Norway
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- Matikainen, Niina (författare)
- Helsinki University Hospital, Helsinki, Finland,Helsinki Univ Hosp, Finland
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- Vehkavaara, Satu (författare)
- Helsinki University Hospital, Helsinki, Finland,Helsinki Univ Hosp, Finland
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- Metso, Saara (författare)
- Tampere University Hospital, Tampere, Finland,Tampere Univ Hosp, Finland
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- Jaatinen, Pia (författare)
- Tampere University Hospital, Tampere, Finland,Tampere Univ Hosp, Finland
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- Hämäläinen, Päivi (författare)
- Tampere University Hospital, Tampere, Finland,Tampere Univ Hosp, Finland
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- Rintamäki, Reeta (författare)
- Kuopio University Hospital, Kuopio, Finland,Kuopio Univ Hosp, Finland
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- Yliaska, Iina (författare)
- Oulu University Hospital, Oulu, Finland,Oulu Univ Hosp, Finland
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- Immonen, Heidi (författare)
- Turku University Hospital, Turku, Finland,Turku Univ Hosp, Finland
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- Mäkimattila, Sari (författare)
- Helsinki University Hospital, Helsinki, Finland,Helsinki Univ Hosp, Finland
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- Cederberg-Tamminen, Henna (författare)
- Helsinki University Hospital, Helsinki, Finland,Helsinki Univ Hosp, Finland
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- Viukari, Marianna (författare)
- Helsinki University Hospital, Helsinki, Finland,Helsinki Univ Hosp, Finland
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- Nevalainen, Pasi (författare)
- Tampere University Hospital, Tampere, Finland,Tampere Univ Hosp, Finland
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- Nuutila, Pirjo (författare)
- Turku University Hospital, Turku, Finland,Turku Univ Hosp, Finland
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- Schalin-Jäntti, Camilla (författare)
- Helsinki University Hospital, Helsinki, Finland,Helsinki Univ Hosp, Finland
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- Burman, Pia (författare)
- Skåne University Hospital, Lund University, Malmö, Sweden,Lund Univ, Sweden
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- Jørgensen, Jens Otto Lunde (författare)
- Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark,Aarhus Univ Hosp, Denmark
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(creator_code:org_t)
- 2024
- 2024
- Engelska.
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Ingår i: Clinical Endocrinology. - : John Wiley & Sons. - 0300-0664 .- 1365-2265.
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Objective: Acromegaly is associated with increased morbidity and mortality if left untreated. The therapeutic options include surgery, medical treatment, and radiotherapy. Several guidelines and recommendations on treatment algorithms and follow-up exist. However, not all recommendations are strictly evidence-based. To evaluate consensus on the treatment and follow-up of patients with acromegaly in the Nordic countries.Methods: A Delphi process was used to map the landscape of acromegaly management in Denmark, Sweden, Norway, Finland, and Iceland. An expert panel developed 37 statements on the treatment and follow-up of patients with acromegaly. Dedicated endocrinologists (n = 47) from the Nordic countries were invited to rate their extent of agreement with the statements, using a Likert-type scale (1−7). Consensus was defined as ≥80% of panelists rating their agreement as ≥5 or ≤3 on the Likert-type scale.Results: Consensus was reached in 41% (15/37) of the statements. Panelists agreed that pituitary surgery remains first line treatment. There was general agreement to recommend first-generation somatostatin analog (SSA) treatment after failed surgery and to consider repeat surgery. In addition, there was agreement to recommend combination therapy with first-generation SSA and pegvisomant as second- or third-line treatment. In more than 50% of the statements, consensus was not achieved. Considerable disagreement existed regarding pegvisomant monotherapy, and treatment with pasireotide and dopamine agonists.Conclusion: This consensus exploration study on the management of patients with acromegaly in the Nordic countries revealed a relatively large degree of disagreement among experts, which mirrors the complexity of the disease and the shortage of evidence-based data.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Nyckelord
- acromegaly
- Delphi
- dopamine agonist
- growth hormone
- growth hormone receptor antagonist
- insulin-like growth factor i
- somatostatin
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Arlien-Søborg, M ...
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Dal, Jakob
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Heck, Ansgar
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Stochholm, Kirst ...
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Husted, Eigil
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Feltoft, Claus L ...
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visa fler...
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Rasmussen, Åse K ...
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Feldt-Rasmussen, ...
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Andreassen, Mikk ...
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Klose, Marianne ...
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Nielsen, Torben ...
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Andersen, Marian ...
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Christensen, Lou ...
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Krogh, Jesper
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Jarlov, Anne
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Bollerslev, Jens
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Nermoen, Ingrid
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Oksnes, Marianne
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Dahlqvist, Per
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Olsson, Tommy
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Berinder, Katari ...
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Hoybye, Charlott ...
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Petersson, Maria
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Akerman, Anna-ka ...
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Wahlberg, Jeanet ...
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Ekman, Bertil
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Engstrom, Britt ...
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Johannsson, Gudm ...
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Ragnarsson, Oska ...
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Olsson, Daniel
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Sigurjónsdóttir, ...
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Fougner, Stine L ...
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Matikainen, Niin ...
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Vehkavaara, Satu
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Metso, Saara
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Jaatinen, Pia
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Hämäläinen, Päiv ...
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Rintamäki, Reeta
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Yliaska, Iina
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Immonen, Heidi
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Mäkimattila, Sar ...
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Cederberg-Tammin ...
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Viukari, Mariann ...
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Nevalainen, Pasi
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Nuutila, Pirjo
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Schalin-Jäntti, ...
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Burman, Pia
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Jørgensen, Jens ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Endokrinologi oc ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Anestesi och int ...
- Artiklar i publikationen
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Clinical Endocri ...
- Av lärosätet
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Umeå universitet
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Linköpings universitet