Increased long-term mortality in patients less than 55 years old who have undergone knee replacement for osteoarthritis - Results from the Swedish knee arthroplasty register

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Fältnamn	Indikatorer	Metadata
000		03752naa a2200325 4500
001		oai:lup.lub.lu.se:95878b43-8203-45f5-96e9-58550e1012ae
003		SwePub
008		160401s2007 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://lup.lub.lu.se/record/6464262 URI
024	7	a https://doi.org/10.1302/0301-620X.89B5.183552 DOI
040		a (SwePub)lu
041		a engb eng
042		9 SwePub
072	7	a art2 swepub-publicationtype
072	7	a ref2 swepub-contenttype
100	1	a Robertsson, Ottou Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ort-otto
245	1 0	a Increased long-term mortality in patients less than 55 years old who have undergone knee replacement for osteoarthritis - Results from the Swedish knee arthroplasty register
264	1	c 2007
520		a Patients with osteoarthritis undergoing knee replacement have been reported to have an overall reduced mortality compared with that of the general population. This has been attributed to the selection of healthier patients for surgery. However, previous studies have had a maximum follow-up time of ten years. We have used information from the Swedish Knee Arthroplasty Register to study the mortality of a large national series of patients with total knee replacement for up to 28 years after surgery and compared their mortality with that of the normal population. In addition, for a subgroup of patients operated on between 1980 and 2002 we analysed their registered causes of death to determine if they differed from those expected. We found a reduced overall mortality during the first 12 post-operative years after which it increased and became significantly higher than that of the general population. Age-specific analysis indicated an inverse correlation between age and mortality, where the younger the patients were, the higher their mortality. The shift at 12 years was caused by a relative over-representation of younger patients with a longer follow-up. Analysis of specific causes of death showed a higher mortality for cardiovascular, gastrointestinal and urogenital diseases. The observation that early onset of osteoarthritis of the knee which has been treated by total knee replacement is linked to an increased mortality should be a reason for increased general awareness of health problems in these patients.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Ortopedi0 (SwePub)302112 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Orthopaedics0 (SwePub)302112 hsv//eng
700	1	a Stefansdottir, Annau Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ort-as2
700	1	a Lidgren, Larsu Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ort-lli
700	1	a Ranstam, T.4 aut
710	2	a Ortopedi, Lundb Sektion III4 org
773	0	t Journal of Bone and Joint Surgery: British Volumeg 89B:5, s. 599-603q 89B:5<599-603x 2044-5377
856	4	u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=%2017540743dopt=Abstractx freey FULLTEXT
856	4	u http://dx.doi.org/10.1302/0301-620X.89B5.18355y FULLTEXT
856	4 8	u https://lup.lub.lu.se/record/646426
856	4 8	u https://doi.org/10.1302/0301-620X.89B5.18355

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Av författaren/redakt...: Robertsson, Otto; Stefansdottir, A ...; Lidgren, Lars; Ranstam, T.

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Ortopedi

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Av lärosätet: Lunds universitet

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