Sökning: onr:"swepub:oai:DiVA.org:su-223941" > Fluorine Mass Balan...
Fältnamn | Indikatorer | Metadata |
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000 | 03303naa a2200469 4500 | |
001 | oai:DiVA.org:su-223941 | |
003 | SwePub | |
008 | 231127s2023 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-2239412 URI |
024 | 7 | a https://doi.org/10.1021/acs.est.3c036552 DOI |
040 | a (SwePub)su | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Cioni, Lara4 aut |
245 | 1 0 | a Fluorine Mass Balance, including Total Fluorine, Extractable Organic Fluorine, Oxidizable Precursors, and Target Per- and Polyfluoroalkyl Substances, in Pooled Human Serum from the Tromsø Population in 1986, 2007, and 2015 |
264 | 1 | c 2023 |
338 | a print2 rdacarrier | |
520 | a Of the thousands of per- and polyfluoroalkyl substances (PFAS) known to exist, only a small fraction (≤1%) are commonly monitored in humans. This discrepancy has led to concerns that human exposure may be underestimated. Here, we address this problem by applying a comprehensive fluorine mass balance (FMB) approach, including total fluorine (TF), extractable organic fluorine (EOF), total oxidizable precursors (TOP), and selected target PFAS, to human serum samples collected over a period of 28 years (1986, 2007, and 2015) in Tromsø, Norway. While concentrations of TF did not change between sampling years, EOF was significantly higher in 1986 compared to 2007 and 2015. The ∑12PFAS concentrations were highest in 2007 compared to 1986 and 2015, and unidentified EOF (UEOF) decreased from 1986 (46%) to 2007 (10%) and then increased in 2015 (37%). While TF and EOF were not influenced by sex, women had higher UEOF compared to men, opposite to target PFAS. This is the first FMB in human serum to include TOP, and it suggests that precursors with >4 perfluorinated carbon atoms make a minor contribution to EOF (0–4%). Additional tools are therefore needed to identify substances contributing to the UEOF in human serum. | |
650 | 7 | a NATURVETENSKAPx Geovetenskap och miljövetenskapx Miljövetenskap0 (SwePub)105022 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Earth and Related Environmental Sciencesx Environmental Sciences0 (SwePub)105022 hsv//eng |
653 | a human exposure | |
653 | a PFAS | |
653 | a PFAA precursors | |
653 | a TF | |
653 | a EOF | |
653 | a TOP assay | |
653 | a time trend | |
700 | 1 | a Plassmann, Merle,d 1981-u Stockholms universitet,Institutionen för miljövetenskap4 aut0 (Swepub:su)mples |
700 | 1 | a Benskin, Jonathan P.,d 1981-u Stockholms universitet,Institutionen för miljövetenskap4 aut0 (Swepub:su)jbens |
700 | 1 | a Coêlho, Ana Carolina M. F.4 aut |
700 | 1 | a Nøst, Therese H.4 aut |
700 | 1 | a Rylander, Charlotta4 aut |
700 | 1 | a Nikiforov, Vladimir4 aut |
700 | 1 | a Sandanger, Torkjel M.4 aut |
700 | 1 | a Herzke, Dorte4 aut |
710 | 2 | a Stockholms universitetb Institutionen för miljövetenskap4 org |
773 | 0 | t Environmental Science and Technologyg 57:40, s. 14849-14860q 57:40<14849-14860x 0013-936Xx 1520-5851 |
856 | 4 | u https://doi.org/10.1021/acs.est.3c03655y Fulltext |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-223941 |
856 | 4 8 | u https://doi.org/10.1021/acs.est.3c03655 |
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