WFRF:(Savic Ana)
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LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 09178naa a2201261 4500 | |
| 001 | oai:DiVA.org:umu-153722 | |
| 003 | SwePub | |
| 008 | 181127s2018 | |||||||||||000 ||eng| | |
| 009 | oai:lup.lub.lu.se:76b70b44-2df4-423a-80aa-0b92fc13a828 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1537222 URI |
| 024 | 7 | a https://doi.org/10.1038/s41467-018-05890-22 DOI |
| 024 | 7 | a https://lup.lub.lu.se/record/76b70b44-2df4-423a-80aa-0b92fc13a8282 URI |
| 040 | a (SwePub)umud (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Ferreiro-Iglesias, Aidau International Agency for Research on Cancer, World Health Organization4 aut |
| 245 | 1 0 | a Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity |
| 264 | c 2018-09-25 | |
| 264 | 1 | b Nature Publishing Group,c 2018 |
| 338 | a electronic2 rdacarrier | |
| 520 | a Lung cancer has several genetic associations identified within the major histocompatibility complex (MHC); although the basis for these associations remains elusive. Here, we analyze MHC genetic variation among 26,044 lung cancer patients and 20,836 controls densely genotyped across the MHC, using the Illumina Illumina OncoArray or Illumina 660W SNP microarray. We impute sequence variation in classical HLA genes, fine-map MHC associations for lung cancer risk with major histologies and compare results between ethnicities. Independent and novel associations within HLA genes are identified in Europeans including amino acids in the HLA-B*0801 peptide binding groove and an independent HLA-DQB1*06 loci group. In Asians, associations are driven by two independent HLA allele sets that both increase risk in HLA-DQB1*0401 and HLA-DRB1*0701; the latter better represented by the amino acid Ala-104. These results implicate several HLA-tumor peptide interactions as the major MHC factor modulating lung cancer susceptibility. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 700 | 1 | a Lesseur, Corinau International Agency for Research on Cancer, World Health Organization4 aut |
| 700 | 1 | a McKay, Jamesu International Agency for Research on Cancer, World Health Organization4 aut |
| 700 | 1 | a Hung, Rayjean J.u University of Toronto4 aut |
| 700 | 1 | a Han, Younghunu Dartmouth College4 aut |
| 700 | 1 | a Zong, Xuchenu University of Toronto4 aut |
| 700 | 1 | a Christiani, Davidu Massachusetts General Hospital,Dartmouth College4 aut |
| 700 | 1 | a Johansson, Mattiasu International Agency for Research on Cancer, World Health Organization4 aut |
| 700 | 1 | a Xiao, Xiangjunu Dartmouth College4 aut |
| 700 | 1 | a Li, Yafangu Dartmouth College4 aut |
| 700 | 1 | a Qian, David C.u University of Washington4 aut |
| 700 | 1 | a Ji, Xuemeiu Dartmouth College4 aut |
| 700 | 1 | a Liu, Geoffreyu University of Toronto4 aut |
| 700 | 1 | a Caporaso, Neilu National Cancer Institute, USA4 aut |
| 700 | 1 | a Scelo, Ghislaineu International Agency for Research on Cancer, World Health Organization4 aut |
| 700 | 1 | a Zaridze, Davidu N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences4 aut |
| 700 | 1 | a Mukeriya, Anushu N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences4 aut |
| 700 | 1 | a Kontic, Milicau Clinical Center of Serbia4 aut |
| 700 | 1 | a Ognjanovic, Simonau International Organization for Cancer Prevention and Research4 aut |
| 700 | 1 | a Lissowska, Jolantau The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology4 aut |
| 700 | 1 | a Szolkowska, Malgorzatau National Tuberculosis and Lung Diseases Research Institute4 aut |
| 700 | 1 | a Swiatkowska, Beatau Nofer Institute of Occupational Medicine4 aut |
| 700 | 1 | a Janout, Vladimiru Palacký University4 aut |
| 700 | 1 | a Holcatova, Ivanau Charles University in Prague4 aut |
| 700 | 1 | a Bolca, Ciprianu National Institute of Pneumology M. Nasta4 aut |
| 700 | 1 | a Savic, Milanu Clinical Center of Serbia4 aut |
| 700 | 1 | a Ognjanovic, Miodragu International Organization for Cancer Prevention and Research4 aut |
| 700 | 1 | a Bojesen, Stig Egilu University of Copenhagen,Gentofte Hospital4 aut |
| 700 | 1 | a Wu, Xifengu University of Texas4 aut |
| 700 | 1 | a Albanes, Demetriosu National Cancer Institute, USA4 aut |
| 700 | 1 | a Aldrich, Melinda C.u Vanderbilt University4 aut |
| 700 | 1 | a Tardon, Adoninau University of Oviedo4 aut |
| 700 | 1 | a Fernandez-Somoano, Anau University of Oviedo4 aut |
| 700 | 1 | a Fernandez-Tardon, Guillermou University of Oviedo4 aut |
| 700 | 1 | a Le Marchand, Loicu University of Hawaii at Manoa4 aut |
| 700 | 1 | a Rennert, Gadiu Carmel Medical Center4 aut |
| 700 | 1 | a Chen, Chu4 aut |
| 700 | 1 | a Doherty, Jenniferu Fred Hutchinson Cancer Research Center,University of Washington4 aut |
| 700 | 1 | a Goodman, Garyu Swedish Medical Center4 aut |
| 700 | 1 | a Bickeboeller, Heikeu University Medical Center Göttingen4 aut |
| 700 | 1 | a Wichmann, H-Erichu Helmholtz Zentrum München,Technical University of Munich,World Orthopaedic Concern4 aut |
| 700 | 1 | a Risch, Angelau University Hospital Heidelberg,University of Salzburg,German Center for Lung Research (DZL)4 aut |
| 700 | 1 | a Rosenberger, Albertu University Medical Center Göttingen4 aut |
| 700 | 1 | a Shen, Hongbingu Nanjing Medical University4 aut |
| 700 | 1 | a Dai, Junchengu Nanjing Medical University4 aut |
| 700 | 1 | a Field, John K.u University of Liverpool4 aut |
| 700 | 1 | a Davies, Michaelu University of Liverpool4 aut |
| 700 | 1 | a Woll, Penellau University of Sheffield4 aut |
| 700 | 1 | a Teare, M. Dawnu University of Sheffield4 aut |
| 700 | 1 | a Kiemeney, Lambertus A.u Radboud University Nijmegen,Dartmouth College4 aut |
| 700 | 1 | a van der Heijden, Erik H. F. M.u Radboud University Nijmegen4 aut |
| 700 | 1 | a Yuan, Jian-Minu University of Pittsburgh Cancer Institute4 aut |
| 700 | 1 | a Hong, Yun-Chulu Seoul National University Hospital4 aut |
| 700 | 1 | a Haugen, Aageu National Institute of Occupational Health, Norway4 aut |
| 700 | 1 | a Zienolddiny, Shanbehu National Institute of Occupational Health, Norway4 aut |
| 700 | 1 | a Lam, Stephenu British Columbia Cancer Agency4 aut |
| 700 | 1 | a Tsao, Ming-Soundu Princess Margaret Hospital University of Toronto4 aut |
| 700 | 1 | a Johansson, Mikaelu Umeå University,Umeå universitet,Onkologi4 aut0 (Swepub:lu)ftf-mjo |
| 700 | 1 | a Grankvist, Kjellu Umeå University,Umeå universitet,Klinisk kemi4 aut0 (Swepub:umu)kjgr0002 |
| 700 | 1 | a Schabath, Matthew B.u H. Lee Moffitt Cancer Center & Research Institute4 aut |
| 700 | 1 | a Andrew, Angeline4 aut |
| 700 | 1 | a Duell, Ericu Catalan Institute of Oncology4 aut |
| 700 | 1 | a Melander, Olleu Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)endo-ome |
| 700 | 1 | a Brunnström, Hansu Lund University,Lunds universitet,Förbättrad diagnostik och prognostik vid lungcancer och metastaser till lunga,Forskargrupper vid Lunds universitet,Improved diagnostics and prognostics of lung cancer and metastases to the lungs,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-hsb |
| 700 | 1 | a Lazarus, Philipu Washington State University4 aut |
| 700 | 1 | a Arnold, Susanneu University of Kentucky Medical Center4 aut |
| 700 | 1 | a Slone, Staceyu University of Kentucky Medical Center4 aut |
| 700 | 1 | a Byun, Jinyoungu Dartmouth College4 aut |
| 700 | 1 | a Kamal, Ahsanu Dartmouth College4 aut |
| 700 | 1 | a Zhu, Dakaiu Dartmouth College4 aut |
| 700 | 1 | a Landi, Maria Teresau National Cancer Institute, USA4 aut |
| 700 | 1 | a Amos, Christopher, Iu Dartmouth College4 aut |
| 700 | 1 | a Brennan, Paulu International Agency for Research on Cancer, World Health Organization4 aut |
| 710 | 2 | a International Agency for Research on Cancer, World Health Organizationb University of Toronto4 org |
| 773 | 0 | t Nature Communicationsd : Nature Publishing Groupg 9q 9x 2041-1723 |
| 856 | 4 | u https://doi.org/10.1038/s41467-018-05890-2y Fulltext |
| 856 | 4 | u https://umu.diva-portal.org/smash/get/diva2:1266167/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://www.nature.com/articles/s41467-018-05890-2.pdf |
| 856 | 4 | u http://dx.doi.org/10.1038/s41467-018-05890-2x freey FULLTEXT |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-153722 |
| 856 | 4 8 | u https://doi.org/10.1038/s41467-018-05890-2 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/76b70b44-2df4-423a-80aa-0b92fc13a828 |
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