Genetic loci influencing kidney function and chronic kidney disease

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Fältnamn	Indikatorer	Metadata
000		06351naa a2201453 4500
001		oai:lup.lub.lu.se:19f98906-09b8-4ccd-8d8f-b7f361c16278
003		SwePub
008		160401s2010 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:120375065
024	7	a https://lup.lub.lu.se/record/16190282 URI
024	7	a https://doi.org/10.1038/ng.5662 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1203750652 URI
040		a (SwePub)lud (SwePub)ki
041		a engb eng
042		9 SwePub
072	7	a art2 swepub-publicationtype
072	7	a ref2 swepub-contenttype
100	1	a Chambers, John C.4 aut
245	1 0	a Genetic loci influencing kidney function and chronic kidney disease
264		c 2010-04-11
264	1	b Springer Science and Business Media LLC,c 2010
520		a Using genome-wide association, we identify common variants at 2p12-p13, 6q26, 17q23 and 19q13 associated with serum creatinine, a marker of kidney function (P = 10(-10) to 10(-15)). Of these, rs10206899 (near NAT8, 2p12-p13) and rs4805834 (near SLC7A9, 19q13) were also associated with chronic kidney disease (P = 5.0 x 10(-5) and P = 3.6 x 10(-4), respectively). Our findings provide insight into metabolic, solute and drug-transport pathways underlying susceptibility to chronic kidney disease.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng
700	1	a Zhang, Weihua4 aut
700	1	a Lord, Graham M.4 aut
700	1	a van der Harst, Pim4 aut
700	1	a Lawlor, Debbie A.4 aut
700	1	a Sehmi, Joban S.4 aut
700	1	a Gale, Daniel P.4 aut
700	1	a Wass, Mark N.4 aut
700	1	a Ahmadi, Kourosh R.4 aut
700	1	a Bakker, Stephan J. L.4 aut
700	1	a Beckmann, Jacqui4 aut
700	1	a Bilo, Henk J. G.4 aut
700	1	a Bochud, Murielle4 aut
700	1	a Brown, Morris J.4 aut
700	1	a Caulfield, Mark J.4 aut
700	1	a Connell, John M. C.4 aut
700	1	a Cook, H. Terence4 aut
700	1	a Cotlarciuc, Ioana4 aut
700	1	a Smith, George Davey4 aut
700	1	a de Silva, Ranil4 aut
700	1	a Deng, Guohong4 aut
700	1	a Devuyst, Olivier4 aut
700	1	a Dikkeschei, Lambert D.4 aut
700	1	a Dimkovic, Nada4 aut
700	1	a Dockrell, Mark4 aut
700	1	a Dominiczak, Anna4 aut
700	1	a Ebrahim, Shah4 aut
700	1	a Eggermann, Thomas4 aut
700	1	a Farrall, Martin4 aut
700	1	a Ferrucci, Luigi4 aut
700	1	a Floege, Jurgen4 aut
700	1	a Forouhi, Nita G.4 aut
700	1	a Gansevoort, Ron T.4 aut
700	1	a Han, Xijin4 aut
700	1	a Hedblad, Bou Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)medf-bhe
700	1	a van der Heide, Jaap J. Homan4 aut
700	1	a Hepkema, Bouke G.4 aut
700	1	a Hernandez-Fuentes, Maria4 aut
700	1	a Hypponen, Elina4 aut
700	1	a Johnson, Toby4 aut
700	1	a de Jong, Paul E.4 aut
700	1	a Kleefstra, Nanne4 aut
700	1	a Lagou, Vasiliki4 aut
700	1	a Lapsley, Marta4 aut
700	1	a Li, Yun4 aut
700	1	a Loos, Ruth J. F.4 aut
700	1	a Luan, Jian'an4 aut
700	1	a Luttropp, Karinu Karolinska Institutet4 aut
700	1	a Marechal, Celine4 aut
700	1	a Melander, Olleu Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups4 aut0 (Swepub:lu)endo-ome
700	1	a Munroe, Patricia B.4 aut
700	1	a Nordfors, Louiseu Karolinska Institutet4 aut
700	1	a Parsa, Afshin4 aut
700	1	a Peltonen, Leena4 aut
700	1	a Penninx, Brenda W.4 aut
700	1	a Perucha, Esperanza4 aut
700	1	a Pouta, Anneli4 aut
700	1	a Prokopenko, Inga4 aut
700	1	a Roderick, Paul J.4 aut
700	1	a Ruokonen, Aimo4 aut
700	1	a Samani, Nilesh J.4 aut
700	1	a Sanna, Serena4 aut
700	1	a Schalling, Martinu Karolinska Institutet4 aut
700	1	a Schlessinger, David4 aut
700	1	a Schlieper, Georg4 aut
700	1	a Seelen, Marc A. J.4 aut
700	1	a Shuldiner, Alan R.4 aut
700	1	a Sjögren, Marketau Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Kardiovaskulär forskning - hypertoni,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Cardiovascular Research - Hypertension4 aut0 (Swepub:lu)endo-msj
700	1	a Smit, Johannes H.4 aut
700	1	a Snieder, Harold4 aut
700	1	a Soranzo, Nicole4 aut
700	1	a Spector, Timothy D.4 aut
700	1	a Stenvinkel, Peteru Karolinska Institutet4 aut
700	1	a Sternberg, Michael J. E.4 aut
700	1	a Swaminathan, Ramasamyiyer4 aut
700	1	a Tanaka, Toshiko4 aut
700	1	a Ubink-Veltmaat, Lielith J.4 aut
700	1	a Uda, Manuela4 aut
700	1	a Vollenweider, Peter4 aut
700	1	a Wallace, Chris4 aut
700	1	a Waterworth, Dawn4 aut
700	1	a Zerres, Klaus4 aut
700	1	a Waeber, Gerard4 aut
700	1	a Wareham, Nicholas J.4 aut
700	1	a Maxwell, Patrick H.4 aut
700	1	a McCarthy, Mark I.4 aut
700	1	a Jarvelin, Marjo-Riitta4 aut
700	1	a Mooser, Vincent4 aut
700	1	a Abecasis, Goncalo R.4 aut
700	1	a Lightstone, Liz4 aut
700	1	a Scott, James4 aut
700	1	a Navis, Gerjan4 aut
700	1	a Elliott, Paul4 aut
700	1	a Kooner, Jaspal S.4 aut
710	2	a Kardiovaskulär forskning - epidemiologib Forskargrupper vid Lunds universitet4 org
773	0	t Nature Geneticsd : Springer Science and Business Media LLCg 42:5, s. 373-375q 42:5<373-375x 1546-1718x 1061-4036
856	4	u http://dx.doi.org/10.1038/ng.566y FULLTEXT
856	4	u https://europepmc.org/articles/pmc3748585?pdf=render
856	4 8	u https://lup.lub.lu.se/record/1619028
856	4 8	u https://doi.org/10.1038/ng.566
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:120375065

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Av författaren/redakt...: Chambers, John C ...; Zhang, Weihua; Lord, Graham M.; van der Harst, P ...; Lawlor, Debbie A ...; Sehmi, Joban S.; visa fler...; Gale, Daniel P.; Wass, Mark N.; Ahmadi, Kourosh ...; Bakker, Stephan ...; Beckmann, Jacqui; Bilo, Henk J. G.; Bochud, Murielle; Brown, Morris J.; Caulfield, Mark ...; Connell, John M. ...; Cook, H. Terence; Cotlarciuc, Ioan ...; Smith, George Da ...; de Silva, Ranil; Deng, Guohong; Devuyst, Olivier; Dikkeschei, Lamb ...; Dimkovic, Nada; Dockrell, Mark; Dominiczak, Anna; Ebrahim, Shah; Eggermann, Thoma ...; Farrall, Martin; Ferrucci, Luigi; Floege, Jurgen; Forouhi, Nita G.; Gansevoort, Ron ...; Han, Xijin; Hedblad, Bo; van der Heide, J ...; Hepkema, Bouke G ...; Hernandez-Fuente ...; Hypponen, Elina; Johnson, Toby; de Jong, Paul E.; Kleefstra, Nanne; Lagou, Vasiliki; Lapsley, Marta; Li, Yun; Loos, Ruth J. F.; Luan, Jian'an; Luttropp, Karin; Marechal, Celine; Melander, Olle; Munroe, Patricia ...; Nordfors, Louise; Parsa, Afshin; Peltonen, Leena; Penninx, Brenda ...; Perucha, Esperan ...; Pouta, Anneli; Prokopenko, Inga; Roderick, Paul J ...; Ruokonen, Aimo; Samani, Nilesh J ...; Sanna, Serena; Schalling, Marti ...; Schlessinger, Da ...; Schlieper, Georg; Seelen, Marc A. ...; Shuldiner, Alan ...; Sjögren, Marketa; Smit, Johannes H ...; Snieder, Harold; Soranzo, Nicole; Spector, Timothy ...; Stenvinkel, Pete ...; Sternberg, Micha ...; Swaminathan, Ram ...; Tanaka, Toshiko; Ubink-Veltmaat, ...; Uda, Manuela; Vollenweider, Pe ...; Wallace, Chris; Waterworth, Dawn; Zerres, Klaus; Waeber, Gerard; Wareham, Nichola ...; Maxwell, Patrick ...; McCarthy, Mark I ...; Jarvelin, Marjo- ...; Mooser, Vincent; Abecasis, Goncal ...; Lightstone, Liz; Scott, James; Navis, Gerjan; Elliott, Paul; Kooner, Jaspal S ...; visa färre...

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Av lärosätet: Lunds universitet; Karolinska Institutet

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