SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Wendl Michael)
 

Sökning: WFRF:(Wendl Michael) > Initial sequence of...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008380naa a2201129 4500
001oai:DiVA.org:uu-108258
003SwePub
008090910s2005 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1082582 URI
0247 a https://doi.org/10.1038/nature040722 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Mikkelsen, Tarjeiu Broad Institute4 aut
2451 0a Initial sequence of the chimpanzee genome and comparison with the human genome
264 1b Springer Science and Business Media LLC,c 2005
338 a print2 rdacarrier
520 a Here we present a draft genome sequence of the common chimpanzee (Pan troglodytes). Through comparison with the human genome, we have generated a largely complete catalogue of the genetic differences that have accumulated since the human and chimpanzee species diverged from our common ancestor, constituting approximately thirty-five million single-nucleotide changes, five million insertion/deletion events, and various chromosomal rearrangements. We use this catalogue to explore the magnitude and regional variation of mutational forces shaping these two genomes, and the strength of positive and negative selection acting on their genes. In particular, we find that the patterns of evolution in human and chimpanzee protein-coding genes are highly correlated and dominated by the fixation of neutral and slightly deleterious alleles. We also use the chimpanzee genome as an outgroup to investigate human population genetics and identify signatures of selective sweeps in recent human evolution.
650 7a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng
653 a Genetics
653 a Genetik
653 a Genetics
653 a Genetik
7001 a Hillier, LaDeanau Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Eichler, Evanu University of Washington, Department of Genome Sciences4 aut
7001 a Zody, Michael,d 1968-u Broad Institute4 aut0 (Swepub:uu)miczo266
7001 a Jaffe, Davidu Broad Institute4 aut
7001 a Yang, Shiaw-Pyngu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Enard, Wolfgangu Max Planck Institute of Evolutionary Anthropology4 aut
7001 a Hellmann, Inesu Max Planck Institute of Evolutionary Anthropology4 aut
7001 a Lindblad-Toh, Kerstinu Broad Institute4 aut
7001 a Altheide, Tashau University of California, San Diego4 aut
7001 a Archidiacono, Nicolettau University of Bari, Department of Genetics and Microbiology4 aut
7001 a Bork, Peeru EMBL4 aut
7001 a Butler, Jonathanu Broad Institute4 aut
7001 a Chang, Jeanu Broad Institute4 aut
7001 a Cheng, Zeu University of Washington, Department of Genome Sciences4 aut
7001 a Chinwalla, Asifu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a de Jong, Pieteru Children's Hospital Oakland Research Institute4 aut
7001 a Delehaunty, Kimberleyu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Fronick, Catrinau Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Fulton, Lucindau Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Gilad, Yoavu Yale University School of Medicine, Department of Genetics4 aut
7001 a Glusman, Gustavou Institute for Systems Biology4 aut
7001 a Gnerre, Santeu Broad Institute4 aut
7001 a Graves, Tinau Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Hayakawa, Toshiyukiu University of California, San Diego4 aut
7001 a Hayden, Karenu Case Western Reserve University, Department of Genetics4 aut
7001 a Huang, Xiaoqiuu Iowa State University, Department of Computer Science4 aut
7001 a Ji, Hongkaiu Harvard University, Department of Statistics4 aut
7001 a Kent, W.u University of California, Santa Cruz, Center for Biomolecular Science and Engineering4 aut
7001 a King, Mary-Claireu University of Washington, Department of Genome Sciences4 aut
7001 a Kulbokas, Edwardu Broad Institute4 aut
7001 a Lee, Mingu University of Washington, Department of Genome Sciences4 aut
7001 a Liu, Geu Case Western Reserve University, Department of Genetics4 aut
7001 a Lopez-Otin, Carlosu Universidad de Oviedo, Instituto Universitario de Oncologia del Principado de Asturias, Departamento de Bioquimica y Biologia Molecular4 aut
7001 a Makova, Katerynau The Pennsylvania State University, Center for Comparative Genomics and Bioinformatics and Department of Biology4 aut
7001 a Man, Ornau Weizmann Institute of Science, Department of Structural Biology4 aut
7001 a Mardis, Elaineu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Mauceli, Evanu Broad Institute4 aut
7001 a Miner, Tracieu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Nash, illiamu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Nelson, Joanneu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Pääbo, Svanteu Max Planck Institute of Evolutionary Anthropology4 aut
7001 a Patterson, Nicku Broad Institute4 aut
7001 a Pohl, Craigu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Pollard, Katherineu University of California, Santa Cruz, Center for Biomolecular Science and Engineering4 aut
7001 a Prüfer, Kayu Max Planck Institute for Evolutionary Anthropology4 aut
7001 a Puente, Xoseu Universidad de Oviedo, Instituto Universitario de Oncologia del Principado de Asturias, Departamento de Bioquimica y Biologia Molecular4 aut
7001 a Reich, Davidu Broad Institute4 aut
7001 a Rocchi, Marianou University of Bari, Department of Genetics and Microbiology4 aut
7001 a Rosenbloom, Kateu University of California, Santa Cruz, Center for Biomolecular Science and Engineering4 aut
7001 a Ruvolo, Maryellenu Harvard University, Department of Anthropology and of Organismic and Evolutionary Biology4 aut
7001 a Richter, Danielu Broad Institute4 aut
7001 a Schaffner, Stephenu Broad Institute4 aut
7001 a Smit, Arianu Institute for Systems Biology4 aut
7001 a Smith, Scottu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Suyama, Mikitau EMBL4 aut
7001 a Taylor, Jamesu The Pennsylvania State University, Center for Comparative Genomics and Bioinformatics and Department of Biology4 aut
7001 a Torrents, Davidu EMBL4 aut
7001 a Tuzun, Erayu University of Washington, Department of Genome Sciences4 aut
7001 a Varki, Ajitu University of California, San Diego4 aut
7001 a Velasco, Gloriau Universidad de Oviedo, Instituto Universitario de Oncologia del Principado de Asturias, Departamento de Bioquimica y Biologia Molecular4 aut
7001 a Ventura, Mariou University of Bari, Department of Genetics and Microbiology4 aut
7001 a Wallis, Johnu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Wendl, Michaelu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Wilson, Richardu Washington University School of Medicine, Genome Sequencing Center4 aut
7001 a Lander, Ericu Broad Institute4 aut
7001 a Waterston, Robertu University of Washington, Department of Genome Sciences4 aut
7102 a Broad Instituteb Washington University School of Medicine, Genome Sequencing Center4 org
7730 t Natured : Springer Science and Business Media LLCg 437:7055, s. 69-87q 437:7055<69-87x 0028-0836x 1476-4687
8564 u https://www.nature.com/articles/nature04072.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-108258
8564 8u https://doi.org/10.1038/nature04072

Hitta via bibliotek

  • Nature (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy