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Onset of molar incisor hypomineralization (MIH).

Fagrell, Tobias G (author)
Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
Salmon, Phil (author)
Melin, Lisa (author)
Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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Norén, Jörgen G, 1947 (author)
Gothenburg University,Göteborgs universitet,Institutionen för odontologi,Institute of Odontology
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 (creator_code:org_t)
2013
2013
English.
In: Swedish dental journal. - 0347-9994. ; 37:2, s. 61-70
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The etiological factors and timing of the onset of molar incisor hypomineralization (MIH) are still not clear. The aim of this study was to examine ground radial and sagittal sections from teeth diagnosed with MIH using light microscopy, polarized light microscopy and X-ray micro-computed tomography (XMCT) and to estimate the onset and timing of the MIH and to relate the hypomineralized enamel to the incremental lines. Thirteen extracted permanent first molars diagnosed MIH, were analyzed with light microscopy and XMCT. The hypomineralized areas were mainly located in the mesio-buccal cusps, starting at the enamel-dentin-junction and continuing towards the enamel surface. In a relative gray scale analysis the values decreased from the EDJ towards the enamel surface. The findings indicate that the ameloblasts in the hypomineralized enamel are capable of forming an enamel of normal thickness, but with a substantial reduction of their capacity for maturation of enamel. Chronologically, it is estimated that the timing of the disturbance is at a period during the first 6-7 months of age.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Annan medicin och hälsovetenskap (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Other Medical and Health Sciences (hsv//eng)

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Fagrell, Tobias ...
Salmon, Phil
Melin, Lisa
Norén, Jörgen G, ...
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MEDICAL AND HEALTH SCIENCES
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Swedish dental j ...
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University of Gothenburg

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