(WFRF:(Mellgren Karin 1962))
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- Mellgren, Karin,1962Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics (author)
Effect of nitric oxide gas on platelets during open heart operations.
- Article/chapterEnglish1998
Publisher, publication year, extent ...
- 1998
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/197834
- https://gup.ub.gu.se/publication/197834URI
Supplementary language notes
- Language:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- The increased bleeding tendency observed after cardiopulmonary bypass is caused in part by thrombocytopenia and impaired platelet function induced by the procedure. Previous in vitro studies have shown that nitric oxide (NO) added to the oxygenator sweep gas reduces platelet activation during experimental perfusion. We evaluated the effect of 40 ppm of NO, added to the oxygenator sweep gas, on platelet consumption and activation in patients undergoing cardiopulmonary bypass.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine hsv//eng
- Adenosine Diphosphate
- pharmacology
- Aged
- Blood Platelets
- drug effects
- physiology
- Cardiopulmonary Bypass
- adverse effects
- instrumentation
- Coronary Artery Bypass
- Female
- Follow-Up Studies
- Heart Valve Prosthesis Implantation
- Hemoglobins
- analysis
- Humans
- Male
- Methemoglobin
- analysis
- Middle Aged
- Nitrates
- blood
- Nitric Oxide
- administration & dosage
- therapeutic use
- Oxygenators
- Platelet Activation
- drug effects
- Platelet Adhesiveness
- drug effects
- Platelet Aggregation
- drug effects
- Platelet Count
- drug effects
- Platelet Glycoprotein GPIIb-IIIa Complex
- analysis
- Platelet Glycoprotein GPIb-IX Complex
- analysis
- drug effects
- Postoperative Hemorrhage
- prevention & control
- Thrombocytopenia
- prevention & control
- beta-Thromboglobulin
- analysis
Added entries (persons, corporate bodies, meetings, titles ...)
- Mellgren, G (author)
- Lundin, Stefan,1953Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för anestesiologi och intensivvård,Institute of Surgical Sciences, Department of Anaesthesiology and Intensive Care(Swepub:gu)xlunds (author)
- Wennmalm, A (author)
- Wadenvik, Hans,1955Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin, Avdelningen för internmedicin,Institute of Internal Medicine, Dept of Medicine(Swepub:gu)xwadha (author)
- Göteborgs universitetInstitutionen för kvinnors och barns hälsa, Avdelningen för pediatrik (creator_code:org_t)
Related titles
- In:The Annals of thoracic surgery65:5, s. 1335-410003-4975
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