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Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial.
- Armitage, Jane (author)
- Bowman, Louise (author)
- Wallendszus, Karl (author)
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- Bulbulia, Richard (author)
- Rahimi, Kazem (author)
- Haynes, Richard (author)
- Parish, Sarah (author)
- Peto, Richard (author)
- Collins, Rory (author)
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- (creator_code:org_t)
- 2010
- 2010
- English.
- In: Lancet. - 1474-547X. ; 376:9753, s. 1658-69
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Lowering of LDL cholesterol reduces major vascular events, but whether more intensive therapy safely produces extra benefits is uncertain. We aimed to establish efficacy and safety of more intensive statin treatment in patients at high cardiovascular risk.
Keyword
- Adult
- Aged
- Aged
- 80 and over
- Anticholesteremic Agents
- administration & dosage
- adverse effects
- Cholesterol
- HDL
- blood
- Cholesterol
- LDL
- blood
- Double-Blind Method
- Female
- Humans
- Hypercholesterolemia
- complications
- drug therapy
- Male
- Middle Aged
- Myocardial Infarction
- blood
- complications
- Simvastatin
- administration & dosage
- Triglycerides
- blood
- Young Adult
Publication and Content Type
- ref (subject category)
- art (subject category)
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- Armitage, Jane
- Bowman, Louise
- Wallendszus, Kar ...
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- Rahimi, Kazem
- Haynes, Richard
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- Parish, Sarah
- Peto, Richard
- Collins, Rory
- Wilhelmsen, Lars ...
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- Lancet
- By the university
- University of Gothenburg
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