Age-time risk patterns of solid cancers in 60 901 non-Hodgkin lymphoma survivors from Finland, Norway and Sweden

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Fältnamn	Indikatorer	Metadata
000		03320naa a2200409 4500
001		oai:lup.lub.lu.se:36017e12-902d-4c49-948b-b996112034e2
003		SwePub
008		160401s2014 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://lup.lub.lu.se/record/43672712 URI
024	7	a https://doi.org/10.1111/bjh.126842 DOI
040		a (SwePub)lu
041		a engb eng
042		9 SwePub
072	7	a art2 swepub-publicationtype
072	7	a ref2 swepub-contenttype
100	1	a Bermejo, Justo Lorenzo4 aut
245	1 0	a Age-time risk patterns of solid cancers in 60 901 non-Hodgkin lymphoma survivors from Finland, Norway and Sweden
264		c 2013-12-04
264	1	b Wiley,c 2014
520		a Survival after non-Hodgkin lymphoma (NHL) has increased thanks to improved treatment but NHL survivors have an increased risk of second neoplasms. The assessment of cancer risk patterns after NHL may help to quantify the late side-effects of therapy. Poisson regression was used to estimate relative risks (RRs) and absolute incidence rates for nine solid tumours based on a nationwide cohort of 60 901 NHL survivors from Finland, Norway and Sweden. Patients were diagnosed between 1980 and 2006 and developed 6815 s neoplasms. NHL patients showed an increased risk of each of the nine investigated cancer sites: prostate and pancreas (both RRs 1.28), breast (1.37), colorectum (1.48), urinary bladder (1.52), stomach and lung (both RRs 1.87), skin (melanoma 2.27) and kidney (2.56). The RRs showed a U-shaped relationship with time after NHL for all nine-second cancer types. NHL diagnosis early in life was a risk factor for the development of second cancers with the exception of melanoma, but a risk excess was even observed in patients diagnosed with NHL at age 80+ years. The present study provides accurate estimates on the adverse late effects of NHL therapy, which should guide the establishment of cancer prevention strategies in NHL survivors.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng
653		a non-Hodgkin lymphoma
653		a second neoplasms
653		a population-based risk estimates
653		a relative risks
653		a absolute risks
700	1	a Pukkala, Eero4 aut
700	1	a Johannesen, Tom B.4 aut
700	1	a Sundquist, Janu Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-jsu
700	1	a Hemminki, Kariu Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-khk
710	2	a Allmänmedicin och klinisk epidemiologib Forskargrupper vid Lunds universitet4 org
773	0	t British Journal of Haematologyd : Wileyg 164:5, s. 675-683q 164:5<675-683x 0007-1048
856	4	u http://dx.doi.org/10.1111/bjh.12684y FULLTEXT
856	4	u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bjh.12684
856	4 8	u https://lup.lub.lu.se/record/4367271
856	4 8	u https://doi.org/10.1111/bjh.12684

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Av författaren/redakt...: Bermejo, Justo L ...; Pukkala, Eero; Johannesen, Tom ...; Sundquist, Jan; Hemminki, Kari

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Hematologi

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Av lärosätet: Lunds universitet

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