Search: AMNE:(MEDICAL AND HEALTH SCIENCES Clinical Medicine Urology and Nephrology)
> (2020-2024) >
Artificial intellig...
Artificial intelligence-based detection of lymph node metastases by PET/CT predicts prostate cancer-specific survival
-
- Borrelli, Pablo (author)
- Sahlgrenska universitetssjukhuset,Sahlgrenska University Hospital
-
- Larsson, Måns, 1989 (author)
- Chalmers University of Technology,Eigenvision AB
-
- Ulén, Johannes (author)
- Eigenvision AB
-
show more...
-
- Enqvist, Olof, 1981 (author)
- Chalmers University of Technology,Eigenvision AB
-
- Trägårdh, Elin (author)
- Lund University,Lunds universitet,Nuklearmedicin, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Nuclear medicine, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital
-
- Poulsen, Mads Hvid (author)
- Syddansk Universitet,University of Southern Denmark,Odense University Hospital
-
- Mortensen, Mike Allan (author)
- Odense University Hospital
-
- Kjölhede, Henrik, 1981 (author)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology,Sahlgrenska University Hospital
-
- Hoilund-Carlsen, Poul Flemming (author)
- Syddansk Universitet,University of Southern Denmark,Odense University Hospital
-
- Edenbrandt, Lars, 1957 (author)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Sahlgrenska University Hospital
-
show less...
-
(creator_code:org_t)
- 2020-10-18
- 2021
- English.
-
In: Clinical Physiology and Functional Imaging. - : Wiley. - 1475-0961 .- 1475-097X. ; 41:1, s. 62-67
- Related links:
-
https://research.cha... (primary) (free)
-
show more...
-
https://findresearch...
-
http://dx.doi.org/10...
-
https://research.cha...
-
https://doi.org/10.1...
-
https://gup.ub.gu.se...
-
https://lup.lub.lu.s...
-
show less...
Abstract
Subject headings
Close
- Introduction Lymph node metastases are a key prognostic factor in prostate cancer (PCa), but detecting lymph node lesions from PET/CT images is a subjective process resulting in inter-reader variability. Artificial intelligence (AI)-based methods can provide an objective image analysis. We aimed at developing and validating an AI-based tool for detection of lymph node lesions. Methods A group of 399 patients with biopsy-proven PCa who had undergone(18)F-choline PET/CT for staging prior to treatment were used to train (n = 319) and test (n = 80) the AI-based tool. The tool consisted of convolutional neural networks using complete PET/CT scans as inputs. In the test set, the AI-based lymph node detections were compared to those of two independent readers. The association with PCa-specific survival was investigated. Results The AI-based tool detected more lymph node lesions than Reader B (98 vs. 87/117;p = .045) using Reader A as reference. AI-based tool and Reader A showed similar performance (90 vs. 87/111;p = .63) using Reader B as reference. The number of lymph node lesions detected by the AI-based tool, PSA, and curative treatment was significantly associated with PCa-specific survival. Conclusion This study shows the feasibility of using an AI-based tool for automated and objective interpretation of PET/CT images that can provide assessments of lymph node lesions comparable with that of experienced readers and prognostic information in PCa patients.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk bildbehandling (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Image Processing (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- fluorocholine
- PCa
- artificial intelligence
- PET
- lymph node metastases
- artificial intelligence
- fluorocholine
- lymph node metastases
- PCa
- PET
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database
- By the author/editor
-
Borrelli, Pablo
-
Larsson, Måns, 1 ...
-
Ulén, Johannes
-
Enqvist, Olof, 1 ...
-
Trägårdh, Elin
-
Poulsen, Mads Hv ...
-
show more...
-
Mortensen, Mike ...
-
Kjölhede, Henrik ...
-
Hoilund-Carlsen, ...
-
Edenbrandt, Lars ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Urology and Neph ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Radiology Nuclea ...
-
- ENGINEERING AND TECHNOLOGY
-
ENGINEERING AND ...
-
and Medical Engineer ...
-
and Medical Image Pr ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cancer and Oncol ...
- Articles in the publication
-
Clinical Physiol ...
- By the university
-
Chalmers University of Technology
-
University of Gothenburg
-
Lund University