Sökning: L773:1043 3074
> (2000-2004) >
Health-related qual...
-
Hammerlid, Eva,1957Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för öron, näs- och halssjukdomar,Institute of Selected Clinical Sciences, Department of Otolaryngology
(författare)
Health-related quality of life three years after diagnosis of head and neck cancer : A longitudinal study
- Artikel/kapitelEngelska2001
Förlag, utgivningsår, omfång ...
Nummerbeteckningar
-
LIBRIS-ID:oai:gup.ub.gu.se/252815
-
https://gup.ub.gu.se/publication/252815URI
-
https://doi.org/10.1002/1097-0347(200102)23:2<113::aid-hed1006>3.0.co;2-wDOI
Kompletterande språkuppgifter
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
Purpose. To examine health-related quality of life (HRQL) of all head and neck cancer patients from diagnosis until 3 years later and to analyze its dependence on tumor site and other patient characteristics. Subjects and Methods. Two hundred thirty-two patients (mean age 61 years; 70% men) were included and followed with clinical measures and mailed standardized HRQL questionnaires (The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-80 (EORTC QLQ-C30), the EORTC QLQ-Head and Neck Cancer module (QLQ-H&N35), and the Hospital Anxiety and Depression Scale (HADS). Results. After 3 years 66 % of the patients were alive and 88 % of these completed the study. The HRQL was worse during treatment and returned slowly thereafter to pretreatment values with few exceptions. After 3 years the best improvement was found for mental distress, followed by a significant global quality of life improvement and reduced pain compared with diagnosis. A significant deterioration was found for problems with dry mouth, senses, and teeth, as well as for opening the mouth wide tie, they seemed to be related to the treatment given). There were few significant improvements between the 1- and 3-year follow-ups. Depression and physical functioning at diagnosis were independent predictors for global quality of life at 3 years. Patients who died during the study had a worse HRQL at diagnosis compared with patients completing the study. Patients with advanced disease (stage III + IV) scored worse than patients with small tumors for most of the HRQL domains. These differences increased over time. Few differences were found relating to gender and age. The pharyngeal cancer group scored worse compared with the other tumor sites, and these patients would probably benefit from a rehabilitation program right from diagnosis, including treatment for malnutrition and pain. Conclusions. The largest HRQL changes for head and neck cancer patients are seen within the first year after diagnosis, with a significant deterioration just after finishing treatment. Thereafter, most of the variables return to pretreatment values. The significant problems with dry mouth, senses, and teeth after treatment are constant over time. (C) 2001 John Wiley & Sons, Inc.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Silander, Ewa M,1952Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för öron, näs- och halssjukdomar,Institute of Selected Clinical Sciences, Department of Otolaryngology(Swepub:gu)xsilew
(författare)
-
Hornestam, L.Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för öron, näs- och halssjukdomar,Institute of Selected Clinical Sciences, Department of Otolaryngology
(författare)
-
Sullivan, Marianne,1943Gothenburg University,Göteborgs universitet,Institutionen för invärtesmedicin,Institute of Internal Medicine(Swepub:gu)xsulma
(författare)
-
Göteborgs universitetInstitutionen för särskilda specialiteter, Avdelningen för öron, näs- och halssjukdomar
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Head and Neck-Journal for the Sciences and Specialties of the Head and Neck23:2, s. 113-1251043-3074
Internetlänk
Hitta via bibliotek
Till lärosätets databas