Sökning: WFRF:(Gackowski D.) > Interlaboratory com...
Fältnamn | Indikatorer | Metadata |
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000 | 03905naa a2200637 4500 | |
001 | oai:gup.ub.gu.se/109826 | |
003 | SwePub | |
008 | 240910s2009 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/1098262 URI |
024 | 7 | a https://doi.org/10.1080/135475008027060122 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Cooke, Marcus S4 aut |
245 | 1 0 | a Interlaboratory comparison of methodologies for the measurement of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine. |
264 | c 2009-03 | |
264 | 1 | b Informa UK Limited,c 2009 |
520 | a Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) is widely used as a marker of oxidative stress. Here we report the comparison of two, distinct chromatographic assays with an enzyme-linked immunosorbent assay (ELISA). The chromatographic assays displayed good agreement (r =:0.89, p < 0.0001), whereas there was markedly worse, albeit still significant, agreement with the ELISA (high-pressure liquid chromatography followed by gas chromatography (HPLC-GC/MS), r = 0.43; HPLC with electrochemical detection (HPLC-EC), r = 0.56; p < 0.0001). Mean values differed significantly between the chromatographic assays and the ELISA (HPLC-GC/MS 3.86, HPLC-EC 4.20, ELISA 18.70 ng mg(-1) creatinine; p < 0.0001). While it is reassuring to note good agreement between chromatographic assays, this study reveals significant short-comings in the ELISA, which brings into question its continued use in its present form. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Dermatologi och venereologi0 (SwePub)302042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dermatology and Venereal Diseases0 (SwePub)302042 hsv//eng |
653 | a Adult | |
653 | a Chromatography | |
653 | a High Pressure Liquid | |
653 | a Creatinine | |
653 | a urine | |
653 | a Deoxyguanosine | |
653 | a analogs & derivatives | |
653 | a urine | |
653 | a Electrochemistry | |
653 | a Enzyme-Linked Immunosorbent Assay | |
653 | a Gas Chromatography-Mass Spectrometry | |
653 | a Humans | |
653 | a Laboratories | |
653 | a Male | |
653 | a Middle Aged | |
700 | 1 | a Barregård, Lars,d 1948u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xbarrl |
700 | 1 | a Mistry, Vilas4 aut |
700 | 1 | a Potdar, Neelam4 aut |
700 | 1 | a Rozalski, Rafal4 aut |
700 | 1 | a Gackowski, Daniel4 aut |
700 | 1 | a Siomek, Agnieszka4 aut |
700 | 1 | a Foksinski, Marek4 aut |
700 | 1 | a Svoboda, Peter4 aut |
700 | 1 | a Kasai, Hiroshi4 aut |
700 | 1 | a Konje, Justin C4 aut |
700 | 1 | a Sällsten, Gerd,d 1952u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xsalge |
700 | 1 | a Evans, Mark D4 aut |
700 | 1 | a Olinski, Ryszard4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa4 org |
773 | 0 | t Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicalsd : Informa UK Limitedg 14:2, s. 103-10q 14:2<103-10x 1366-5804 |
773 | 0 | t Biomarkersd : Informa UK Limitedg 14:2, s. 103-10q 14:2<103-10x 1354-750X |
856 | 4 | u https://figshare.com/articles/journal_contribution/Inter-laboratory_comparison_of_methodologies_for_the_measurement_of_urinary_8-oxo-7_8-dihydro-2_-deoxyguanosine_/10084472/1/files/18182675.pdf |
856 | 4 8 | u https://gup.ub.gu.se/publication/109826 |
856 | 4 8 | u https://doi.org/10.1080/13547500802706012 |
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