WFRF:(Janson Veronica)
Sökning: WFRF:(Janson Veronica) > Inhaled corticoster...
Inhaled corticosteroids and risk of osteoporosis in late-middle age subjects : a multicenter European cohort study
- Grosso, Amelia (författare)
- Cerveri, Isa (författare)
- Cazzoletti, Lucia (författare)
- visa fler...
- Zanolin, Maria E (författare)
- Mattioli, Veronica (författare)
- Piloni, Davide (författare)
- Gini, Erica (författare)
- Albicini, Federica (författare)
- Ronzoni, Vanessa (författare)
- Jarvis, Debbie (författare)
- Corsico, Angelo G (författare)
- visa färre...
- (creator_code:org_t)
- Edizioni Minerva Medica, 2023
- 2023
- Engelska.
- Ingår i: Minerva Medica. - : Edizioni Minerva Medica. - 0026-4806 .- 1827-1669. ; 114:1
- Tidskriftsartikel (refereegranskat)
Abstract
Ämnesord
Stäng
- BACKGROUND: Inhaled corticosteroids have been widely used for the regular treatment of asthma and COPD over the past few decades. To date, studies investigating the effects of ICS on bone in populations including asthma and COPD patients, show conflicting results. The skeletal effects of ICS remain poorly understood. We assessed the association between ICS exposure and self-reported osteoporosis diagnosis in a European cohort study.METHODS: The analysis was carried out by using clinical and questionnaire data available for subjects participating in the ECRHS III (European Community Respiratory Health Survey) with age >55 years.RESULTS: Among the 3004 enrolled subjects, 245 were ICS users with an exposure ≥12 months. Osteoporosis was reported by 16 subjects in the ICS group (6.5%) and by 167 in the not exposed group (6.1%). The adjusted risk of osteoporosis in ICS users (≥12 months) was not greater in exposed subjects when compared with the unexposed ones (OR=1.02, 95CI%: 0.51, 2.03). The same result was observed even when considering in the analysis a longer exposure to the ICS use (≥ 36.5 months, the median ICS exposure for all subjects). History of COPD, use of oral corticosteroids, Body Mass Index, smoking and physical activity did not show any evidence of an association with osteoporosis.CONCLUSIONS: Our study did not show any significant association between long- term ICS use and self-reported diagnosis of osteoporosis in subjects aged >55 years. To explore the real effect of ICS on bone status, further studies are needed, especially in the long-term ICS exposure.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta mer i SwePub
- Av författaren/redakt...
- Grosso, Amelia
- Cerveri, Isa
- Cazzoletti, Luci ...
- Zanolin, Maria E
- Mattioli, Veroni ...
- Piloni, Davide
- visa fler...
- Gini, Erica
- Albicini, Federi ...
- Ronzoni, Vanessa
- Jarvis, Debbie
- Janson, Christer
- Corsico, Angelo ...
- visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Klinisk medicin
- och Lungmedicin och ...
- Artiklar i publikationen
- Minerva Medica
- Av lärosätet
- Uppsala universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
