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Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia A

Eckhardt, CL (author)
Astermark, Jan (author)
Lund University,Lunds universitet,Klinisk koagulationsmedicin, Malmö,Forskargrupper vid Lunds universitet,Clinical Coagulation, Malmö,Lund University Research Groups
Peters, M (author)
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Astermark, J (author)
Brons, PP (author)
Castaman, G (author)
Cnossen, MH (author)
Karolinska Institutet
Dors, N (author)
Escuriola-Ettingshausen, C (author)
Hamulyak, K (author)
Hart, DP (author)
Hay, CRM (author)
Haya, S (author)
van Heerde, WL (author)
Hermans, C (author)
Holmstrom, M (author)
Karolinska Institutet
Jimenez-Yuste, V (author)
Keenan, RD (author)
Klamroth, R (author)
Gorkom, BAP (author)
Leebeek, FWG (author)
Liesner, R (author)
Makipernaa, A (author)
Male, C (author)
Mauser-Bunschoten, E (author)
Mazzucconi, MG (author)
Mcrae, S (author)
Meijer, K (author)
Mitchell, M (author)
Morfini, M (author)
Nijziel, M (author)
Oldenburg, J (author)
Peerlinck, K (author)
Petrini, P (author)
Platokouki, H (author)
Reitter-Pfoertner, SE (author)
Santagostino, E (author)
Schinco, P (author)
Smiers, FJ (author)
Siegmund, B (author)
Tagliaferri, A (author)
Yee, TT (author)
Kamphuisen, PW (author)
van der Bom, JG (author)
Fijnvandraat, K (author)
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 (creator_code:org_t)
American Society of Hematology, 2013
2013
English.
In: Blood. - : American Society of Hematology. - 1528-0020 .- 0006-4971. ; 122:11, s. 1954-1962
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The inhibitor incidence in nonsevere hemophilia A patients with certain F8 mutations approaches the inhibitor incidence in severe patients. These findings are highly relevant for clinical practice, as they facilitate identification of high-risk patients based on F8 genotype.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Hematologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Hematology (hsv//eng)

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