Sökning: WFRF:(Johansson Anders J) > (2005-2009) > The use of clinical...
Fältnamn | Indikatorer | Metadata |
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000 | 06526naa a2201165 4500 | |
001 | oai:gup.ub.gu.se/106046 | |
003 | SwePub | |
008 | 240528s2007 | |||||||||||000 ||eng| | |
009 | oai:research.chalmers.se:eb62df84-e4f1-480f-8cfd-f6e0816d3947 | |
009 | oai:lup.lub.lu.se:b819da38-8ada-497f-a0f7-a70116a74105 | |
024 | 7 | a https://gup.ub.gu.se/publication/1060462 URI |
024 | 7 | a https://doi.org/10.1007/s00198-007-0343-y2 DOI |
024 | 7 | a https://research.chalmers.se/publication/1060462 URI |
024 | 7 | a https://lup.lub.lu.se/record/6486982 URI |
040 | a (SwePub)gud (SwePub)cthd (SwePub)lu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Kanis, J A4 aut |
245 | 1 0 | a The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women. |
264 | c 2007-02-24 | |
264 | 1 | b Springer Science and Business Media LLC,c 2007 |
520 | a SUMMARY: BMD and clinical risk factors predict hip and other osteoporotic fractures. The combination of clinical risk factors and BMD provide higher specificity and sensitivity than either alone. INTRODUCTION AND HYPOTHESES: To develop a risk assessment tool based on clinical risk factors (CRFs) with and without BMD. METHODS: Nine population-based studies were studied in which BMD and CRFs were documented at baseline. Poisson regression models were developed for hip fracture and other osteoporotic fractures, with and without hip BMD. Fracture risk was expressed as gradient of risk (GR, risk ratio/SD change in risk score). RESULTS: CRFs alone predicted hip fracture with a GR of 2.1/SD at the age of 50 years and decreased with age. The use of BMD alone provided a higher GR (3.7/SD), and was improved further with the combined use of CRFs and BMD (4.2/SD). For other osteoporotic fractures, the GRs were lower than for hip fracture. The GR with CRFs alone was 1.4/SD at the age of 50 years, similar to that provided by BMD (GR = 1.4/SD) and was not markedly increased by the combination (GR = 1.4/SD). The performance characteristics of clinical risk factors with and without BMD were validated in eleven independent population-based cohorts. CONCLUSIONS: The models developed provide the basis for the integrated use of validated clinical risk factors in men and women to aid in fracture risk prediction. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Fysiologi0 (SwePub)301062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Physiology0 (SwePub)301062 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Ortopedi0 (SwePub)302112 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Orthopaedics0 (SwePub)302112 hsv//eng |
653 | a Age Factors | |
653 | a Aged | |
653 | a Aged | |
653 | a 80 and over | |
653 | a Area Under Curve | |
653 | a Bone Density | |
653 | a physiology | |
653 | a Female | |
653 | a Fractures | |
653 | a Spontaneous | |
653 | a etiology | |
653 | a physiopathology | |
653 | a Hip Fractures | |
653 | a etiology | |
653 | a physiopathology | |
653 | a Humans | |
653 | a Male | |
653 | a Middle Aged | |
653 | a Osteoporosis | |
653 | a complications | |
653 | a physiopathology | |
653 | a Osteoporosis | |
653 | a Postmenopausal | |
653 | a etiology | |
653 | a physiopathology | |
653 | a Risk Assessment | |
653 | a methods | |
653 | a Risk Factors | |
653 | a physiology | |
653 | a fracture | |
653 | a osteoporotic | |
653 | a meta-analysis | |
653 | a bone mineral density | |
653 | a hip fracture | |
653 | a risk assessment | |
700 | 1 | a Odén, Anders,d 1942u Gothenburg University,Göteborgs universitet,Institutionen för matematiska vetenskaper, matematisk statistik,Department of Mathematical Sciences, Mathematical Statistics,University of Gothenburg,Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)odena |
700 | 1 | a Johnell, Olofu Lund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups4 aut0 (Swepub:lu)orto-ojo |
700 | 1 | a Johansson, Helena,d 1981u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,University of Gothenburg4 aut0 (Swepub:gu)xjhell |
700 | 1 | a De Laet, C4 aut |
700 | 1 | a Brown, J4 aut |
700 | 1 | a Burckhardt, P4 aut |
700 | 1 | a Cooper, C4 aut |
700 | 1 | a Christiansen, C4 aut |
700 | 1 | a Cummings, S4 aut |
700 | 1 | a Eisman, J A4 aut |
700 | 1 | a Fujiwara, S4 aut |
700 | 1 | a Glüer, C4 aut |
700 | 1 | a Goltzman, D4 aut |
700 | 1 | a Hans, D4 aut |
700 | 1 | a Krieg, M-A4 aut |
700 | 1 | a La Croix, A4 aut |
700 | 1 | a McCloskey, E4 aut |
700 | 1 | a Mellström, Dan,d 1945u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,University of Gothenburg4 aut0 (Swepub:gu)xmelda |
700 | 1 | a Melton, L J4 aut |
700 | 1 | a Pols, H4 aut |
700 | 1 | a Reeve, J4 aut |
700 | 1 | a Sanders, K4 aut |
700 | 1 | a Schott, A-M4 aut |
700 | 1 | a Silman, A4 aut |
700 | 1 | a Torgerson, D4 aut |
700 | 1 | a van Staa, T4 aut |
700 | 1 | a Watts, N B4 aut |
700 | 1 | a Yoshimura, N4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för matematiska vetenskaper, matematisk statistik4 org |
773 | 0 | t Osteoporosis internationald : Springer Science and Business Media LLCg 18:8, s. 1033-46q 18:8<1033-46x 0937-941Xx 1433-2965 |
856 | 4 | u http://dx.doi.org/10.1007/s00198-007-0343-yy FULLTEXT |
856 | 4 8 | u https://gup.ub.gu.se/publication/106046 |
856 | 4 8 | u https://doi.org/10.1007/s00198-007-0343-y |
856 | 4 8 | u https://research.chalmers.se/publication/106046 |
856 | 4 8 | u https://lup.lub.lu.se/record/648698 |
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