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Community Diarrhea ...
Community Diarrhea Incidence Before and After Rotavirus Vaccine Introduction in Nicaragua
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Becker-Dreps, Sylvia (author)
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Melendez, Marlon (author)
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Liu, Lan (author)
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Enrique Zambrana, Luis (author)
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Paniagua, Margarita (author)
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Weber, David J. (author)
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Hudgens, Michael G. (author)
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Caceres, Mercedes (author)
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- Källestål, Carina, 1954- (author)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa,Internationell barnhälsa och nutrition/Persson
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Morgan, Douglas R. (author)
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Espinoza, Felix (author)
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Pena, Rodolfo (author)
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(creator_code:org_t)
- American Society of Tropical Medicine and Hygiene, 2013
- 2013
- English.
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In: American Journal of Tropical Medicine and Hygiene. - : American Society of Tropical Medicine and Hygiene. - 0002-9637 .- 1476-1645. ; 89:2, s. 246-250
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https://europepmc.or...
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https://urn.kb.se/re...
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https://doi.org/10.4...
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Abstract
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- We estimated the incidence of watery diarrhea in the community before and after introduction of the pentavalent rotavirus vaccine in Leon, Nicaragua. A random sample of households was selected before and after rotavirus vaccine introduction. All children < 5 years of age in selected households were eligible for inclusion. Children were followed every 2 weeks for watery diarrhea episodes. The incidence rate was estimated as numbers of episodes per 100 child-years of exposure time. A mixed effects Poisson regression model was fit to compare incidence rates in the pre-vaccine and vaccine periods. The pre-vaccine cohort (N = 726) experienced 36 episodes per 100 child-years, and the vaccine cohort (N = 826) experienced 25 episodes per 100 child-years. The adjusted incidence rate ratio was 0.60 (95% confidence interval [CI] 0.40, 0.91) during the vaccine period versus the pre-vaccine period, indicating a lower incidence of watery diarrhea in the community during the vaccine period.
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- By the author/editor
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Becker-Dreps, Sy ...
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Melendez, Marlon
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Liu, Lan
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Enrique Zambrana ...
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Paniagua, Margar ...
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Weber, David J.
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show more...
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Hudgens, Michael ...
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Caceres, Mercede ...
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Källestål, Carin ...
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Morgan, Douglas ...
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Espinoza, Felix
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Pena, Rodolfo
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show less...
- Articles in the publication
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American Journal ...
- By the university
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Uppsala University