Sökning: WFRF:(Kecklund G) > Increased global FM...
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000 | 04220naa a2200613 4500 | |
001 | oai:DiVA.org:su-143110 | |
003 | SwePub | |
008 | 170512s2017 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:138413218 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1431102 URI |
024 | 7 | a https://doi.org/10.1093/sleepj/zsx050.1062 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1384132182 URI |
040 | a (SwePub)sud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a kon2 swepub-publicationtype |
100 | 1 | a Nilsonne, G.u Karolinska Institutet, Sweden4 aut0 (Swepub:su)guni6529 |
245 | 1 0 | a Increased global FMRI signal variability after partial sleep deprivation :b Findings from the Stockholm sleepy brain study |
264 | c 2017-04-28 | |
264 | 1 | b Oxford University Press (OUP),c 2017 |
338 | a print2 rdacarrier | |
490 | 0 | a Sleep,x 0161-8105x 1550-9109 ;v 40 (suppl_1) |
500 | a This work was supported by Riksbankens Jubileumsfond, Fredrik and Ingrid Thuring’s Foundation, and the Karolinska Institutet Strategic Neuroscience Program. | |
520 | a Introduction: Neural correlates of sleep deprivation are not fully understood and the difference between young and older adults in this regard has received little attention. We aimed to investigate the effect of partial sleep deprivation on resting state connectivity.Methods: 30 younger (20–30 years) and 23 older (65–75 years) healthy participants underwent MR imaging after normal sleep and partial sleep deprivation (3 h sleep). We acquired two runs of eyes-open resting state functional magnetic resonance images. Participants were monitored with eye-tracking to ensure their eyes remained open during scanning.Results: Global signal variability, defined as log-transformed standard deviation of average gray matter signal, was increased following partial sleep deprivation (0.16 [0.07, 0.24], p = 0.0004). In contrast to previous studies, we did not find that partial sleep deprivation inhibited connectivity in the default mode network, nor in other major networks investigated.Conclusion: Sleep deprivation caused increased global signal variability. This novel finding should be confirmed using independent data. Our finding of no difference in default mode connectivity in the sleep deprived state, could possibly be due to stricter monitoring of participants’ wakefulness compared to some earlier studies. | |
650 | 7 | a SAMHÄLLSVETENSKAPx Psykologi0 (SwePub)5012 hsv//swe |
650 | 7 | a SOCIAL SCIENCESx Psychology0 (SwePub)5012 hsv//eng |
653 | a magnetic resonance imaging | |
653 | a neuroscience | |
653 | a sleep deprivation | |
653 | a wakefulness | |
653 | a eye | |
653 | a sleep | |
653 | a functional magnetic resonance imaging | |
653 | a elderly | |
653 | a gray matter | |
653 | a brain research through advancing innovative neurotechnologies study | |
653 | a eye tracking | |
653 | a Psychology | |
653 | a psykologi | |
700 | 1 | a Tamm, S.u Karolinska Institutet, Sweden4 aut0 (Swepub:su)sata4198 |
700 | 1 | a Schwarz, J.u Stockholms universitet,Stressforskningsinstitutet4 aut0 (Swepub:su)jschw |
700 | 1 | a Almeida, R.4 aut |
700 | 1 | a Fischer, H.u Stockholms universitet,Biologisk psykologi4 aut0 (Swepub:su)hkfi4392 |
700 | 1 | a Kecklund, G.u Stockholms universitet,Stressforskningsinstitutet4 aut0 (Swepub:su)gkeck |
700 | 1 | a Lekander, M.u Karolinska Institutet, Sweden4 aut0 (Swepub:su)mleka |
700 | 1 | a Fransson, P.4 aut |
700 | 1 | a Åkerstedt, T.u Stockholms universitet,Stressforskningsinstitutet4 aut0 (Swepub:su)tke |
710 | 2 | a Karolinska Institutet, Swedenb Stressforskningsinstitutet4 org |
773 | 0 | t SLEEPd : Oxford University Press (OUP)g 40, s. A40-A40q 40<A40-A40x 0161-8105x 1550-9109 |
856 | 4 | u https://academic.oup.com/sleep/article-pdf/40/suppl_1/A40/16980250/zsx050.106.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-143110 |
856 | 4 8 | u https://doi.org/10.1093/sleepj/zsx050.106 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:138413218 |
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