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WFRF:(McMurray John J)
 

Sökning: WFRF:(McMurray John J) > (2010-2014) > Relationship betwee...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003761naa a2200565 4500
001oai:gup.ub.gu.se/211936
003SwePub
008240528s2014 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/2119362 URI
0247 a https://doi.org/10.1093/eurheartj/ehu3422 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Badar, A. A.4 aut
2451 0a Relationship between angina pectoris and outcomes in patients with heart failure and reduced ejection fraction: an analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
264 c 2014-09-28
264 1b Oxford University Press (OUP),c 2014
520 a Aim Angina pectoris is common in patients with heart failure and reduced ejection fraction (HF-REF) but its relationship with outcomes has not been well defined. This relationship was investigated further in a retrospective analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA). Methods and results Four thousand, eight hundred and seventy-eight patients were divided into three categories: no history of angina and no chest pain at baseline (Group A; n = 1240), past history of angina but no chest pain at baseline (Group B; n = 1353) and both a history of angina and chest pain at baseline (Group C; n = 2285). Outcomes were examined using Kaplan-Meier and Cox regression survival analysis. Compared with Group A, Group C had a higher risk of non-fatal myocardial infarction or unstable angina (HR: 2.36, 1.54-3.61; P<0.001), this composite plus coronary revascularization (HR: 2.54, 1.76-3.68; P<0.001), as well as HF hospitalization (HR: 1.35, 1.13-1.63; P = 0.001), over a median follow-up period of 33 months. There was no difference in cardiovascular or all-cause mortality. Group B had a smaller increase in risk of coronary events but not of heart failure hospitalization. Conclusion Patients with HF-REF and ongoing angina are at an increased risk of acute coronary syndrome and HF hospitalization. Whether these patients would benefit from more aggressive medical therapy or percutaneous revascularization is not known and merits further investigation.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng
653 a Angina pectoris
653 a Heart failure
653 a Reduced ejection fraction
653 a ISCHEMIC CARDIOMYOPATHY
653 a CLINICAL DETERMINANTS
653 a MORTALITY
653 a PREDICTORS
653 a DISEASE
653 a COMET
653 a Cardiac & Cardiovascular Systems
7001 a Perez-Moreno, A. C.4 aut
7001 a Jhund, P. S.4 aut
7001 a Wong, C. M.4 aut
7001 a Hawkins, N. M.4 aut
7001 a Cleland, J. G. F.4 aut
7001 a van Veldhuisen, D. J.4 aut
7001 a Wikstrand, John,d 1938u Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine4 aut0 (Swepub:gu)xwikjo
7001 a Kjekshus, J.4 aut
7001 a Wedel, Hans4 aut
7001 a Watkins, S.4 aut
7001 a Gardner, R. S.4 aut
7001 a Petrie, M. C.4 aut
7001 a McMurray, J. J. V.4 aut
7102 a Göteborgs universitetb Institutionen för medicin4 org
7730 t European Heart Journald : Oxford University Press (OUP)g 35:48, s. 3426-3433q 35:48<3426-3433x 0195-668Xx 1522-9645
8564 u https://academic.oup.com/eurheartj/article-pdf/35/48/3426/17154671/ehu342.pdf
8564 8u https://gup.ub.gu.se/publication/211936
8564 8u https://doi.org/10.1093/eurheartj/ehu342

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