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Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial.

Dodel, Richard (author)
Rominger, Axel (author)
Bartenstein, Peter (author)
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Barkhof, Frederik (author)
Blennow, Kaj, 1958 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Förster, Stefan (author)
Winter, Yaroslav (author)
Bach, Jan-Philipp (author)
Popp, Julius (author)
Alferink, Judith (author)
Wiltfang, Jens (author)
Buerger, Katharina (author)
Otto, Markus (author)
Antuono, Piero (author)
Jacoby, Michael (author)
Richter, Ralph (author)
Stevens, James (author)
Melamed, Isaac (author)
Goldstein, Jerome (author)
Haag, Stefan (author)
Wietek, Stefan (author)
Farlow, Martin (author)
Jessen, Frank (author)
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 (creator_code:org_t)
2013
2013
English.
In: Lancet neurology. - 1474-4465. ; 12:3, s. 233-43
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Three small trials suggest that intravenous immunoglobulin can affect biomarkers and symptoms of mild-to-moderate Alzheimer's disease. We tested the safety, effective dose, and infusion interval of intravenous immunoglobulin in such patients.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Neurosciences (hsv//eng)

Keyword

Aged
Aged
80 and over
Alzheimer Disease
diagnosis
drug therapy
immunology
Amyloid beta-Peptides
blood
Area Under Curve
Dose-Response Relationship
Drug
Double-Blind Method
Female
Humans
Immunoglobulins
Intravenous
administration & dosage
adverse effects
blood
Male
Middle Aged
Placebos
Severity of Illness Index

Publication and Content Type

ref (subject category)
art (subject category)

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