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Sökning: WFRF:(Wasay Mohammad) > Blood pressure vari...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003756naa a2200469 4500
001oai:gup.ub.gu.se/338081
003SwePub
008240528s2024 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/3380812 URI
0247 a https://doi.org/10.1111/ene.163142 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Reddin, Catriona4 aut
2451 0a Blood pressure variability in acute stroke: Risk factors and association with functional outcomes at 1 month.
264 1c 2024
520 a Blood pressure variability, in acute stroke, may be an important modifiable determinant of functional outcome after stroke. In a large international cohort of participants with acute stroke, it was sought to determine the association of blood pressure variability (in the early period of admission) and functional outcomes, and to explore risk factors for increased blood pressure variability.INTERSTROKE is an international case-control study of risk factors for first acute stroke. Blood pressure was recorded at the time of admission, the morning after admission and the time of interview in cases (median time from admission 36.7h). Multivariable ordinal regression analysis was employed to determine the association of blood pressure variability (standard deviation [SD] and coefficient of variance) with modified Rankin score at 1-month follow-up, and logistic regression was used to identify risk factors for blood pressure variability.Amongst 13,206 participants, the mean age was 62.19 ±13.58years. When measured by SD, both systolic blood pressure variability (odds ratio 1.13; 95% confidence interval 1.03-1.24 for SD ≥20mmHg) and diastolic blood pressure variability (odds ratio 1.15; 95% confidence interval 1.04-1.26 for SD ≥10mmHg) were associated with a significant increase in the odds of poor functional outcome. The highest coefficient of variance category was not associated with a significant increase in risk of higher modified Rankin score at 1 month. Increasing age, female sex, high body mass index, history of hypertension, alcohol use, and high urinary potassium and low urinary sodium excretion were associated with increased blood pressure variability.Increased blood pressure variability in acute stroke, measured by SD, is associated with an increased risk of poor functional outcome at 1month. Potentially modifiable risk factors for increased blood pressure variability include low urinary sodium excretion.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskap0 (SwePub)3032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciences0 (SwePub)3032 hsv//eng
7001 a Murphy, Robert4 aut
7001 a Hankey, Graeme J4 aut
7001 a Wang, Xingyu4 aut
7001 a Langhorne, Peter4 aut
7001 a Oveisgharan, Shahram4 aut
7001 a Xavier, Denis4 aut
7001 a Judge, Conor4 aut
7001 a Rosengren, Annika,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences4 aut0 (Swepub:gu)xrosan
7001 a Iversen, Helle K4 aut
7001 a Czlonkowska, Anna4 aut
7001 a Lanas, Fernando4 aut
7001 a Oguz, Aytekin4 aut
7001 a Ryglewicz, Danuta4 aut
7001 a Wasay, Mohammad4 aut
7001 a Smyth, Andrew4 aut
7001 a Yusuf, Salim4 aut
7001 a O'Donnell, Martin4 aut
7102 a Göteborgs universitetb Institutionen för vårdvetenskap och hälsa4 org
7730 t European journal of neurologyx 1468-1331
8564 8u https://gup.ub.gu.se/publication/338081
8564 8u https://doi.org/10.1111/ene.16314

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