WFRF:(Willeit J)
Sökning: WFRF:(Willeit J) > (2010-2014) > Glycated Hemoglobin...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 07382naa a2201357 4500 | |
| 001 | oai:gup.ub.gu.se/197781 | |
| 003 | SwePub | |
| 008 | 240528s2014 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:uu-224364 | |
| 009 | oai:DiVA.org:umu-88399 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/1977812 URI |
| 024 | 7 | a https://doi.org/10.1001/jama.2014.18732 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2243642 URI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-883992 URI |
| 040 | a (SwePub)gud (SwePub)uud (SwePub)umu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Di Angelantonio, E.4 aut |
| 245 | 1 0 | a Glycated Hemoglobin Measurement and Prediction of Cardiovascular Disease |
| 264 | 1 | b American Medical Association (AMA),c 2014 |
| 500 | a Liisa Byberg är med som collaborator (Uppsala Universitet, Institutionen för kirurgiska vetenskaper, Ortopedi) | |
| 520 | a IMPORTANCE The value of measuring levels of glycated hemoglobin (HbA(1c)) for the prediction of first cardiovascular events is uncertain. OBJECTIVE To determine whether adding information on HbA(1c) values to conventional cardiovascular risk factors is associated with improvement in prediction of cardiovascular disease (CVD) risk. DESIGN, SETTING, AND PARTICIPANTS Analysis of individual-participant data available from 73 prospective studies involving 294 998 participants without a known history of diabetes mellitus or CVD at the baseline assessment. MAIN OUTCOMES AND MEASURES Measures of risk discrimination for CVD outcomes (eg, C-index) and reclassification (eg, net reclassification improvement) of participants across predicted 10-year risk categories of low (<5%), intermediate (5% to <7.5%), and high (>= 7.5%) risk. RESULTS During a median follow-up of 9.9 (interquartile range, 7.6-13.2) years, 20 840 incident fatal and nonfatal CVD outcomes (13 237 coronary heart disease and 7603 stroke outcomes) were recorded. In analyses adjusted for several conventional cardiovascular risk factors, there was an approximately J-shaped association between HbA(1c) values and CVD risk. The association between HbA(1c) values and CVD risk changed only slightly after adjustment for total cholesterol and triglyceride concentrations or estimated glomerular filtration rate, but this association attenuated somewhat after adjustment for concentrations of high-density lipoprotein cholesterol and C-reactive protein. The C-index for a CVD risk prediction model containing conventional cardiovascular risk factors alone was 0.7434 (95% CI, 0.7350 to 0.7517). The addition of information on HbA(1c) was associated with a C-index change of 0.0018 (0.0003 to 0.0033) and a net reclassification improvement of 0.42 (-0.63 to 1.48) for the categories of predicted 10-year CVD risk. The improvement provided by HbA(1c) assessment in prediction of CVD risk was equal to or better than estimated improvements for measurement of fasting, random, or postload plasma glucose levels. CONCLUSIONS AND RELEVANCE In a study of individuals without known CVD or diabetes, additional assessment of HbA(1c) values in the context of CVD risk assessment provided little incremental benefit for prediction of CVD risk. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
| 653 | a STATISTICAL-METHODS | |
| 653 | a DIABETES-MELLITUS | |
| 653 | a RISK SCORE | |
| 653 | a TASK-FORCE | |
| 653 | a GLUCOSE | |
| 653 | a GUIDELINES | |
| 653 | a METAANALYSIS | |
| 653 | a MORTALITY | |
| 653 | a ADULTS | |
| 700 | 1 | a Gao, P.4 aut |
| 700 | 1 | a Khan, H.4 aut |
| 700 | 1 | a Butterworth, A. S.4 aut |
| 700 | 1 | a Wormser, D.4 aut |
| 700 | 1 | a Kaptoge, S.4 aut |
| 700 | 1 | a Seshasai, S. R. K.4 aut |
| 700 | 1 | a Thompson, A.4 aut |
| 700 | 1 | a Sarwar, N.4 aut |
| 700 | 1 | a Willeit, P.4 aut |
| 700 | 1 | a Ridker, P. M.4 aut |
| 700 | 1 | a Barr, E. L. M.4 aut |
| 700 | 1 | a Khaw, K. T.4 aut |
| 700 | 1 | a Psaty, B. M.4 aut |
| 700 | 1 | a Brenner, H.4 aut |
| 700 | 1 | a Balkau, B.4 aut |
| 700 | 1 | a Dekker, J. M.4 aut |
| 700 | 1 | a Lawlor, D. A.4 aut |
| 700 | 1 | a Daimon, M.4 aut |
| 700 | 1 | a Willeit, J.4 aut |
| 700 | 1 | a Njolstad, I.4 aut |
| 700 | 1 | a Nissinen, A.4 aut |
| 700 | 1 | a Brunner, E. J.4 aut |
| 700 | 1 | a Kuller, L. H.4 aut |
| 700 | 1 | a Price, J. F.4 aut |
| 700 | 1 | a Sundström, Johanu Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi4 aut0 (Swepub:uu)johasund |
| 700 | 1 | a Knuiman, M. W.4 aut |
| 700 | 1 | a Feskens, E. J. M.4 aut |
| 700 | 1 | a Verschuren, W. M. M.4 aut |
| 700 | 1 | a Wald, N.4 aut |
| 700 | 1 | a Bakker, S. J. L.4 aut |
| 700 | 1 | a Whincup, P. H.4 aut |
| 700 | 1 | a Ford, I.4 aut |
| 700 | 1 | a Goldbourt, U.4 aut |
| 700 | 1 | a Gomez-de-la-Camara, A.4 aut |
| 700 | 1 | a Gallacher, J.4 aut |
| 700 | 1 | a Simons, L. A.4 aut |
| 700 | 1 | a Rosengren, Annika,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences4 aut0 (Swepub:gu)xrosan |
| 700 | 1 | a Sutherland, S. E.4 aut |
| 700 | 1 | a Björkelund, Cecilia,d 1948u Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine4 aut0 (Swepub:gu)xbjoce |
| 700 | 1 | a Blazer, D. G.4 aut |
| 700 | 1 | a Wassertheil-Smoller, S.4 aut |
| 700 | 1 | a Onat, A.4 aut |
| 700 | 1 | a Ibanez, A. M.4 aut |
| 700 | 1 | a Casiglia, E.4 aut |
| 700 | 1 | a Jukema, J. W.4 aut |
| 700 | 1 | a Simpson, L. M.4 aut |
| 700 | 1 | a Giampaoli, S.4 aut |
| 700 | 1 | a Nordestgaard, B. G.4 aut |
| 700 | 1 | a Selmer, R.4 aut |
| 700 | 1 | a Wennberg, Patriku Umeå universitet,Allmänmedicin4 aut0 (Swepub:umu)pawe0002 |
| 700 | 1 | a Kauhanen, J.4 aut |
| 700 | 1 | a Salonen, J. T.4 aut |
| 700 | 1 | a Dankner, R.4 aut |
| 700 | 1 | a Barrett-Connor, E.4 aut |
| 700 | 1 | a Kavousi, M.4 aut |
| 700 | 1 | a Gudnason, V.4 aut |
| 700 | 1 | a Evans, D.4 aut |
| 700 | 1 | a Wallace, R. B.4 aut |
| 700 | 1 | a Cushman, M.4 aut |
| 700 | 1 | a D'Agostino, R. B.4 aut |
| 700 | 1 | a Umans, J. G.4 aut |
| 700 | 1 | a Kiyohara, Y.4 aut |
| 700 | 1 | a Nakagawa, H.4 aut |
| 700 | 1 | a Sato, S.4 aut |
| 700 | 1 | a Gillum, R. F.4 aut |
| 700 | 1 | a Folsom, A. R.4 aut |
| 700 | 1 | a van der Schouw, Y. T.4 aut |
| 700 | 1 | a Moons, K. G.4 aut |
| 700 | 1 | a Griffin, S. J.4 aut |
| 700 | 1 | a Sattar, N.4 aut |
| 700 | 1 | a Wareham, N. J.4 aut |
| 700 | 1 | a Selvin, E.4 aut |
| 700 | 1 | a Thompson, S. G.4 aut |
| 700 | 1 | a Danesh, J.4 aut |
| 710 | 2 | a Uppsala universitetb Uppsala kliniska forskningscentrum (UCR)4 org |
| 773 | 0 | t Jama-Journal of the American Medical Associationd : American Medical Association (AMA)g 311:12, s. 1225-1233q 311:12<1225-1233x 0098-7484x 1538-3598 |
| 856 | 4 | u https://jamanetwork.com/journals/jama/articlepdf/1852370/joi140019.pdf |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/197781 |
| 856 | 4 8 | u https://doi.org/10.1001/jama.2014.1873 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-224364 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-88399 |
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- Di Angelantonio, ...
- Gao, P.
- Khan, H.
- Butterworth, A. ...
- Wormser, D.
- Kaptoge, S.
- visa fler...
- Seshasai, S. R. ...
- Thompson, A.
- Sarwar, N.
- Willeit, P.
- Ridker, P. M.
- Barr, E. L. M.
- Khaw, K. T.
- Psaty, B. M.
- Brenner, H.
- Balkau, B.
- Dekker, J. M.
- Lawlor, D. A.
- Daimon, M.
- Willeit, J.
- Njolstad, I.
- Nissinen, A.
- Brunner, E. J.
- Kuller, L. H.
- Price, J. F.
- Sundström, Johan
- Knuiman, M. W.
- Feskens, E. J. M ...
- Verschuren, W. M ...
- Wald, N.
- Bakker, S. J. L.
- Whincup, P. H.
- Ford, I.
- Goldbourt, U.
- Gomez-de-la-Cama ...
- Gallacher, J.
- Simons, L. A.
- Rosengren, Annik ...
- Sutherland, S. E ...
- Björkelund, Ceci ...
- Blazer, D. G.
- Wassertheil-Smol ...
- Onat, A.
- Ibanez, A. M.
- Casiglia, E.
- Jukema, J. W.
- Simpson, L. M.
- Giampaoli, S.
- Nordestgaard, B. ...
- Selmer, R.
- Wennberg, Patrik
- Kauhanen, J.
- Salonen, J. T.
- Dankner, R.
- Barrett-Connor, ...
- Kavousi, M.
- Gudnason, V.
- Evans, D.
- Wallace, R. B.
- Cushman, M.
- D'Agostino, R. B ...
- Umans, J. G.
- Kiyohara, Y.
- Nakagawa, H.
- Sato, S.
- Gillum, R. F.
- Folsom, A. R.
- van der Schouw, ...
- Moons, K. G.
- Griffin, S. J.
- Sattar, N.
- Wareham, N. J.
- Selvin, E.
- Thompson, S. G.
- Danesh, J.
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