Sökning: WFRF:(Williams C.) > (1995-1999) > Cloning and charact...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 03558naa a2200541 4500 | |
001 | oai:DiVA.org:kth-13362 | |
003 | SwePub | |
008 | 100615s1998 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:1949025 | |
009 | oai:DiVA.org:uu-52237 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-133622 URI |
024 | 7 | a https://doi.org/10.1006/geno.1998.53092 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19490252 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-522372 URI |
040 | a (SwePub)kthd (SwePub)kid (SwePub)uu | |
041 | a engb engb -1 | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Odeberg, Jacobu Karolinska Institutet,KTH,Bioteknologi4 aut0 (Swepub:kth)u1e4yljo |
245 | 1 0 | a Cloning and characterization of ZNF189, a novel human Krüppel-like zinc finger gene localized to chromosome 9q22-q31. |
264 | 1 | b Elsevier BV,c 1998 |
338 | a print2 rdacarrier | |
500 | a QC 20100615 | |
520 | a A 3-kb-long cDNA encoding a Krüppel-like human zinc finger protein was isolated and mapped to chromosome 9q22-q31. The ZNF189 gene encodes a protein with 16 zinc fingers at its C-terminus and belongs to the Krüppel-associated box (KRAB)-containing group of zinc finger proteins. Four differently spliced cDNA transcripts, differing at the 5' coding region where a KRAB A repressor domain is encoded, were isolated. In addition, Northern blot analysis indicates the presence of two additional unidentified splice variants. Comparison of cDNA and genomic sequences shows that the ZNF189 gene spans approximately 11 kb and is organized into at least four exons, the large 3'-end exon coding for the complete zinc finger domain and the 3' untranslated region. ZNF189 is expressed in all tissues and cell types currently investigated, at varying levels, but with a tissue- or cell-type-restricted expression pattern for the different splice variants. ZNF189 is conserved in the genome of several mammalian species. Direct sequencing of the ZNF189 gene in microdissected tumor biopsies of sporadic basal cell carcinoma and squamous cell carcinoma reveals no mutations in the coding sequence or at exon/intron boundaries. | |
520 | a | |
650 | 7 | a TEKNIK OCH TEKNOLOGIERx Industriell bioteknik0 (SwePub)2092 hsv//swe |
650 | 7 | a ENGINEERING AND TECHNOLOGYx Industrial Biotechnology0 (SwePub)2092 hsv//eng |
653 | a Bioengineering | |
653 | a Bioteknik | |
700 | 1 | a Røsok, O4 aut |
700 | 1 | a Gudmundsson, G H4 aut |
700 | 1 | a Ahmadian, Afshinu KTH,Bioteknologi4 aut0 (Swepub:kth)u1kjb6gb |
700 | 1 | a Roshani, L4 aut |
700 | 1 | a Williams, C4 aut |
700 | 1 | a Larsson, Cu Karolinska Institutet4 aut |
700 | 1 | a Pontén, Fu Uppsala universitet,Institutionen för genetik och patologi4 aut |
700 | 1 | a Uhlén, Mathiasu KTH,Bioteknologi4 aut0 (Swepub:kth)u1dulvmw |
700 | 1 | a Asheim, H C4 aut |
700 | 1 | a Lundeberg, Joakimu KTH,Bioteknologi4 aut0 (Swepub:kth)u1qkn9kw |
700 | 1 | a fl, m4 aut |
710 | 2 | a KTHb Bioteknologi4 org |
773 | 0 | t Genomicsd : Elsevier BVg 50, s. 233-q 50:2<213-21x 0888-7543x 1089-8646 |
773 | 0 | t Genomicsd : Elsevier BVg 50, s. 233-q 50<233- |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-13362 |
856 | 4 8 | u https://doi.org/10.1006/geno.1998.5309 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1949025 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-52237 |
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