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Correlation-based cluster-space transform for major adverse cardiac event prediction
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- Xiao, Yi (author)
- School of Engineering and Information Technology, The University of New South Wales, Canberra, ACT, Australia
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- Pham, Tuan D (author)
- School of Engineering and Information Technology, The University of New South Wales, Canberra, ACT, Australia
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- Jia, Xiuping (author)
- School of Engineering and Information Technology, The University of New South Wales, Canberra, ACT, Australia
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- (creator_code:org_t)
- Institute of Electrical and Electronics Engineers (IEEE), 2010
- 2010
- English.
- In: IEEE International Conference on Systems Man and Cybernetics (SMC). - : Institute of Electrical and Electronics Engineers (IEEE). - 9781424465880 - 9781424465866 ; , s. 2003-2007
- Conference paper (peer-reviewed)
Abstract
Subject headings
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- This paper investigates the affect of variation of patterns in protein profiles to the identification of disease-specific biomarkers. A correlation-based cluster-space transform is applied to mass spectral data for predicting major adverse cardiac events (MACE). Training and testing data are transformed into cluster spaces by correlation distance based clustering, respectively. Data in the testing cluster that falls into a pair of training clusters is classified by a supervised classifier. Experiment results have shown that proteomic spectra of MACE which vary with certain patterns could be separated by the correlation-based clustering. The cluster-space transform allows better classification accuracy than single-clustered class method for separating disease and healthy samples.
Subject headings
- NATURVETENSKAP -- Data- och informationsvetenskap -- Datorseende och robotik (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Computer Vision and Robotics (hsv//eng)
Keyword
- classification; clustering; major adverse cardiac events; mass spectrometry
Publication and Content Type
- ref (subject category)
- kon (subject category)
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- Xiao, Yi
- Pham, Tuan D
- Jia, Xiuping
- Zhou, Xiaobo
- Yan, Hong
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- Linköping University
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