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Unilateral or Bilat...
Unilateral or Bilateral Retroperitoneal Lymph Node Dissection in Nonseminoma Patients with Postchemotherapy Residual Tumour? Results from RETROP, a Population-based Mapping Study by the Swedish Norwegian Testicular Cancer Group
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- Gerdtsson, Axel (författare)
- Karolinska Institutet,Karolinska Institute,Skåne University Hospital,Karolinska Inst, Div Urol, Dept Clin Sci Intervent & Technol, Stockholm, Sweden.;Skane Univ Hosp, Dept Urol, Jan Waldenstroms Gata 5, S-21421 Malmö, Sweden.
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- Thor, Anna (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska Inst, Div Urol, Dept Clin Sci Intervent & Technol, Stockholm, Sweden.;Karolinska Univ Hosp, Dept Urol, Pelv Canc, Stockholm, Sweden.
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- Grenabo Bergdahl, Anna (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology
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- Almås, Bjarte (författare)
- Haukeland University Hospital,Haukeland Hosp, Dept Urol, Bergen, Norway.
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- Håkansson, Ulf (författare)
- Skåne University Hospital,Gastrocenter, Lund, Sweden.
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- Törnblom, Magnus (författare)
- Karolinska Institute,Karolinska Inst, Urol Sect, Dept Clin Sci & Educ, Sodersjukhuset, Stockholm, Sweden.;Visby Cty Hosp, Dept Surg, Visby, Sweden.
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- Negaard, Helene F.S. (författare)
- Oslo university hospital,Oslo Univ Hosp, Dept Oncol, Oslo, Norway.
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- Glimelius, Ingrid, 1975- (författare)
- Uppsala universitet,Karolinska Institutet,Uppsala University,Institutionen för immunologi, genetik och patologi
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- Halvorsen, Dag (författare)
- St. Olav’s University Hospital,St Olavs Univ Hosp, Dept Urol, Trondheim, Norway.
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- Karlsdóttir, Ása (författare)
- Haukeland University Hospital,Haukeland Hosp, Dept Oncol, Bergen, Norway.
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- Sagstuen Haugnes, Hege (författare)
- University Hospital of North Norway,Univ Hosp North Norway, Dept Oncol, Tromso, Norway.;UIT Arctic Univ Norway, Dept Clin Med, Tromso, Norway.
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- Engen Andreassen, Kristine (författare)
- Oslo university hospital,Oslo Univ Hosp, Dept Oncol, Oslo, Norway.
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- Melsen Larsen, Signe (författare)
- Oslo university hospital,Oslo Univ Hosp, Dept Urol, Oslo, Norway.
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- Holmberg, Göran (författare)
- Sahlgrenska University Hospital,Sahlgrens Univ Hosp, Dept Urol, Gothenburg, Sweden.
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- Wahlqvist, Rolf (författare)
- Oslo university hospital,Oslo Univ Hosp, Dept Urol, Oslo, Norway.
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- Tandstad, Torgrim (författare)
- St. Olav’s University Hospital,St Olavs Univ Hosp, Canc Clin, Trondheim, Norway.;Norwegian Univ Sci & Technol, Dept Clin & Mol Med, Trondheim, Norway.
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- Cohn-Cedermark, Gabriella (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska Inst, Dept Oncol Pathol, Stockholm, Sweden.;Karolinska Univ Hosp, Dept Pelv Canc, Genitourinary Oncol Unit, Stockholm, Sweden.
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- Ståhl, Olof (författare)
- Lund University,Lunds universitet,Medicinsk onkologi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical oncology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Skane Univ Hosp, Dept Oncol, Lund, Sweden.;Lund Univ, Dept Clin Sci, Lund, Sweden.
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- Kjellman, Anders (författare)
- Karolinska Institutet,Karolinska Institute,Karolinska Inst, Div Urol, Dept Clin Sci Intervent & Technol, Stockholm, Sweden.;Karolinska Univ Hosp, Dept Urol, Pelv Canc, Stockholm, Sweden.
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(creator_code:org_t)
- Elsevier BV, 2022
- 2022
- Engelska 9 s.
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Ingår i: European Urology Oncology. - : Elsevier BV. - 2588-9311. ; 5:2, s. 235-243
- Relaterad länk:
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http://dx.doi.org/10...
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http://euoncology.eu...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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https://urn.kb.se/re...
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https://gup.ub.gu.se...
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Abstract
Ämnesord
Stäng
- BACKGROUND: The distribution of retroperitoneal lymph node metastases for patients with nonseminoma and a residual tumour of 10-49 mm in a population-based setting is unknown. This information is needed to justify selection of patients for a unilateral template resection. OBJECTIVE: To describe the location of retroperitoneal metastases and recurrences in patients with nonseminoma germ cell tumour (NSGCT) with a residual tumour of 10-49 mm. DESIGN, SETTING, AND PARTICIPANTS: RETROP is a population-based prospective observational mapping study of 213 patients in Sweden and Norway with a retroperitoneal residual tumour of 10-49 mm who underwent postchemotherapy retroperitoneal lymph node dissection for metastatic NSGCT during 2007-2014 with median follow-up of 100 mo. Patients were classified according to the testis primary tumour and the distribution of unilateral or bilateral lymph node metastases (with reference to the aorta) present on pre- and/or postchemotherapy computed tomography (CT) scans. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: The distribution and rate of teratoma or cancer in unilateral or bilateral retroperitoneal fields and the location and rate of retroperitoneal recurrence were measured. RESULTS AND LIMITATIONS: In total, 65% of the patients had unilateral retroperitoneal lymph node metastases (RLNMs) on CT scans. Patients with unilateral RLNMs had a low risk of contralateral teratoma or cancer (1.6% for right- and 2.6% for left-sided NSGCT) or retroperitoneal recurrence (0% for right- and 4% for left-sided NSGCT). A weakness of the study is that the pathology specimen could not be fully designated to one specific area for some of the patients. CONCLUSIONS: Men with postchemotherapy residual disease of 10-49 mm and unilateral metastases on pre- and postchemotherapy CT scans have a low risk of contralateral disease and should be considered for a unilateral template resection. PATIENT SUMMARY: The surgeon can use computed tomography (CT) scans in deciding on the extent of lymph node dissection in patients with testicular cancer.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
- LANTBRUKSVETENSKAPER -- Veterinärmedicin -- Klinisk vetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Veterinary Science -- Clinical Science (hsv//eng)
Nyckelord
- Bilateral
- Mapping study
- Nonseminoma
- Postchemotherapy retroperitoneal lymph node dissection
- Recurrence
- Testicular cancer
- Unilateral
- Bilateral
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Gerdtsson, Axel
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Thor, Anna
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Grenabo Bergdahl ...
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Almås, Bjarte
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Håkansson, Ulf
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Törnblom, Magnus
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visa fler...
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Negaard, Helene ...
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Glimelius, Ingri ...
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Halvorsen, Dag
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Karlsdóttir, Ása
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Sagstuen Haugnes ...
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Engen Andreassen ...
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Melsen Larsen, S ...
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Holmberg, Göran
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Wahlqvist, Rolf
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Tandstad, Torgri ...
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Cohn-Cedermark, ...
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Ståhl, Olof
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Kjellman, Anders
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- Artiklar i publikationen
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European Urology ...
- Av lärosätet
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Lunds universitet
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Karolinska Institutet
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Uppsala universitet
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