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Left ventricular hy...
Left ventricular hypertrophy in adults with previous repair of coarctation of the aorta : association with systolic blood pressure in the high normal range
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- Rinnström, Daniel, 1982- (author)
- Umeå universitet,Kardiologi,Umeå University, Sweden,Umea Univ Hosp, Ctr Heart, Umea, Sweden.,Umeå University Hospital,Heart Centre
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- Dellborg, Mikael, 1954 (author)
- Gothenburg University,Göteborgs universitet,University of Gothenburg,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Univ Gothenburg, Dept Mol & Clin Med, Gothenburg, Sweden.
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- Thilén, Ulf (author)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund Univ, Dept Cardiol, Clin Sci, Lund, Sweden.
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- Sörensson, Peder (author)
- Karolinska Institute,Karolinska Institutet,Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden.
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- Nielsen, Niels Erik (author)
- Linköping University,Linköpings universitet,Avdelningen för kardiovaskulär medicin,Hälsouniversitetet,Region Östergötland, Kardiologiska kliniken US,Linkoping Univ, Dept Med & Hlth Sci, Linkoping, Sweden.
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- Christersson, Christina (author)
- Uppsala universitet,Koagulation och inflammationsvetenskap,Kardiologi,Uppsala kliniska forskningscentrum (UCR),Uppsala University, Sweden,Institutionen för medicinska vetenskaper
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- Johansson, Bengt (author)
- Umeå universitet,Kardiologi,Umeå University, Sweden,Umea Univ Hosp, Ctr Heart, Umea, Sweden.,Umeå University Hospital,Heart Centre
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(creator_code:org_t)
- Elsevier BV, 2016
- 2016
- English.
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In: International Journal of Cardiology. - : Elsevier BV. - 0167-5273 .- 1874-1754. ; 37, s. 369-369
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Abstract
Subject headings
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- Background: Arterial hypertension is common in adults with repaired coarctation of the aorta (CoA). The associations between the diagnosis of hypertension, actual blood pressure, other factors affecting left ventricular overload, and left ventricular hypertrophy (LVH) are not yet fully explored in this population. Material and results: From the national register for congenital heart disease, 506 adult patients (>= 18 years old) with previous repair of CoA were identified (37.0% female, mean age 35.7 +/- 13.8 years, with an average of 26.8 +/- 12.4 years post repair). Echocardiographic data were available for all patients, and showed LVH in 114 (22.5%) of these. Systolic blood pressure (SBP) (mm Hg) (OR 1.02, CI 1.01-1.04), aortic valve disease, (OR 2.17, CI 1.33-3.53), age (years) (OR 1.03, CI 1.01-1.05), diagnosis of arterial hypertension (OR 3.02, CI 1.81-5.02), and sex (female) (OR 0.41, CI 0.24-0.72) were independently associated with LVH. There was an association with LVH at SBP within the upper reference limits [ 130, 140] mm Hg (OR 2.23, CI 1.05-4.73) that further increased for SBP > 140 mm Hg (OR 8.02, CI 3.76-17.12). Conclusions: LVH is common post repair of CoA and is associated with SBP even below the currently recommended target level. Lower target levels may therefore become justified in this population. ORCID Id: 0000-0003-0976-6910
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- CoA
- Hypertension
- Left ventricular hypertrophy
- Adult congenital heart disease
- Adult congenital heart disease
- CoA
- Hypertension
- Left ventricular hypertrophy
- Adult congenital heart disease; CoA; Hypertension; Left ventricular hypertrophy
Publication and Content Type
- ref (subject category)
- art (subject category)
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