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Stent thrombosis ra...
Stent thrombosis rates the first year and beyond with new- and old-generation drug-eluting stents compared to bare metal stents
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- Varenhorst, Christoph, 1977- (författare)
- Uppsala University,Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi
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- Lindholm, Martin (författare)
- Västerås County Hospital, Sweden,Vasteras Cty Hosp, Dept Internal Med, Cardiol, Vasteras, Sweden,Västmanland Hospital
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- Sarno, Giovanna (författare)
- Uppsala University,Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi
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- Olivecrona, Göran (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Jensens, Ulf (författare)
- Karolinska Institutet
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- Nilsson, Johan (författare)
- Umeå universitet,Kardiologi,Umeå University, Sweden,Umea Univ, Heart Ctr, Dept Cardiol, Umea, Sweden
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- Carlsson, Jörg (författare)
- Linnaeus University,Linnéuniversitetet,Institutionen för hälso- och vårdvetenskap (HV),Linnaeus Univ, Fac Hlth & Life Sci, Kalmar, Sweden
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- James, Stefan K, 1964- (författare)
- Uppsala University,Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)
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- Lagerqvist, Bo, 1952- (författare)
- Uppsala University,Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi
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(creator_code:org_t)
- 2018-04-17
- 2018
- Engelska.
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Ingår i: Clinical Research in Cardiology. - : Springer. - 1861-0684 .- 1861-0692. ; 107:9, s. 816-823
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Old-generation drug-eluting coronary stents (o-DES) have despite being safe and effective been associated with an increased propensity of late stent thrombosis (ST). We evaluated ST rates in o-DES, new-generation DES (n-DES) and bare metal stents (BMS) the first year (< 1 year) and beyond 1 year (> 1 year). We evaluated all implantations with BMS, o-DES (Cordis Cypher, Boston Scientific Taxus Libert, and Medtronic Endeavor) and n-DES in the Swedish coronary angiography and angioplasty registry (SCAAR) between 1 January 2007 and 8 January 2014 (n = 207 291). All cases of ST (n = 2 268) until 31 December 2014 were analyzed. The overall risk of ST was lower in both n-DES and o-DES compared with BMS up to 1 year (n-DES versus BMS: adjusted risk ratio (RR) 0.48 (0.41-0.58) and o-DES versus BMS: 0.56 (0.46-0.67), both p < 0.001). From 1 year after stent implantation and onward, the risk for ST was higher in o-DES compared with BMS [adjusted RR, 1.82 (1.47-2.25], p < 0.001). N-DES were associated with similar low ST rates as BMS from 1 year and onward [adjusted RR 1.21 (0.94-1.56), p = 0.135]. New-generation DES were associated with lower ST rates in comparison to BMS during the first-year post-stenting. After 1 year, n-DES and BMS were associated with similar ST rates. This study was a retrospective observational study and as such did not require clinical trial database registration.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Bare metal stents
- Drug-eluting stents
- Stent thrombosis
- Percutaneous coronary intervention
- Omvårdnad
- Nursing
- Bare metal stents
- Drug-eluting stents
- Percutaneous coronary intervention
- Stent thrombosis
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Varenhorst, Chri ...
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Lindholm, Martin
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Sarno, Giovanna
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Olivecrona, Göra ...
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Jensens, Ulf
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Nilsson, Johan
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Carlsson, Jörg
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James, Stefan K, ...
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Lagerqvist, Bo, ...
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- MEDICIN OCH HÄLSOVETENSKAP
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- Av lärosätet
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Linnéuniversitetet
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Umeå universitet
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Uppsala universitet
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Karolinska Institutet
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Lunds universitet