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Sökning: L773:1088 9051 > (2000-2004) > Bichir HoxA cluster...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003056naa a2200445 4500
001oai:lup.lub.lu.se:630cbb5a-d9c4-4ed1-be22-870191a81057
003SwePub
008160401s2004 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/2900962 URI
024a https://doi.org/10.1101/gr.17129042 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Chiu, CH4 aut
2451 0a Bichir HoxA cluster sequence reveals surprising trends in ray-finned fish genomic evolution
264 c 2004-01-05
264 1b Cold Spring Harbor Laboratory,c 2004
520 a The study of Hox clusters and genes provides insights into the evolution of genomic regulation of development. Derived ray-finned fishes (Actinopterygii, Teleostei) such as zebrafish and pufferfish possess duplicated Hox clusters that have undergone considerable sequence evolution. Whether these changes are associated with the duplication(s) that produced extra Hox clusters is unresolved because comparison with basal lineages is unavailable. We sequenced and analyzed the HoxA cluster of the bichir (Polypterus senegalus), a phylogenetically basal actinopterygian. Independent lines of evidence indicate that bichir has one HoxA cluster that is mosaic in its patterns of noncoding sequence conservation and gene retention relative to the HoxA clusters of human and shark, and the HoxAalpha and HoxAbeta clusters of zebrafish, pufferfish, and striped bass. HoxA cluster noncoding sequences conserved between bichir and euteleosts indicate that novel cis-sequences were acquired in the stem actinopterygians and maintained after cluster duplication. Hence, in the earliest actinopterygians, evolution of the single HoxA cluster was already more dynamic than in human and shark. This tendency peaked among teleosts after HoxA cluster duplication.
650 7a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng
700a Dewar, K4 aut
700a Wagner, GP4 aut
700a Takahashi, K4 aut
700a Ruddle, F4 aut
700a Ledje, Christinau Lund University,Lunds universitet,Biologiska institutionen,Naturvetenskapliga fakulteten,Department of Biology,Faculty of Science4 aut0 (Swepub:lu)gen-cle
700a Bartsch, P4 aut
700a Scemama, JL4 aut
700a Stellwag, E4 aut
700a Fried, C4 aut
700a Prohaska, SJ4 aut
700a Stadler, PF4 aut
700a Amemiya, CT4 aut
710a Biologiska institutionenb Naturvetenskapliga fakulteten4 org
773t Genome Researchd : Cold Spring Harbor Laboratoryg 14:1, s. 11-17q 14:1<11-17x 1549-5469x 1088-9051
856u http://dx.doi.org/10.1101/gr.1712904x freey FULLTEXT
856u http://genome.cshlp.org/content/14/1/11.full.pdf
8564 8u https://lup.lub.lu.se/record/290096
8564 8u https://doi.org/10.1101/gr.1712904

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