Limited evidence for the use of imaging to detect prostate cancer: a systematic review

Limited evidence for the use of imaging to detect prostate cancer : a systematic review

Gjertsson, P. (author): Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden

Heintz, E. (author): The Swedish Council on Health Technology Assessment, Stockholm, Sweden

Hultcrantz, M. (author): The Swedish Council on Health Technology Assessment, Stockholm, Sweden

Mejare, I. (author): The Swedish Council on Health Technology Assessment, Stockholm, Sweden

Andrén, Ove, 1963- (author): Örebro universitet,Institutionen för hälsovetenskap och medicin,Region Örebro län,Department of Urology, Örebro University Hospital, Örebro, Sweden

(creator_code:org_t)

Elsevier, 2014
2014
English.
In: European Journal of Radiology. - : Elsevier. - 0720-048X .- 1872-7727. ; 83:9, s. 1601-1606

Related links:: https://urn.kb.se/re...; show more...; https://doi.org/10.1...; http://kipublication...; show less...

Abstract Subject headings

Objective: To assess the diagnostic accuracy of imaging technologies for detecting prostate cancer in patients with elevated PSA-values or suspected findings on clinical examination.Methods: The databases Medline, EMBASE, Cochrane, CRD HTA/DARE/NHS EED and EconLit were searched until June 2013. Pre-determined inclusion criteria were used to select full text articles. Risk of bias in individual studies was rated according to QUADAS or AMSTAR. Abstracts and full text articles were assessed independently by two reviewers. The performance of diagnostic imaging was compared with systematic biopsies (reference standard) and sensitivity and specificity were calculated.Results: The literature search yielded 5141 abstracts, which were reviewed by two independent reviewers. Of these 4852 were excluded since they did not meet the inclusion criteria. 288 articles were reviewed in full text for quality assessment. Six studies, three using MRI and three using transrectal ultrasound were included. All were rated as high risk of bias. Relevant studies on PET/CT were not identified.Conclusion: Despite clinical use, there is insufficient evidence regarding the accuracy of imaging technologies for detecting cancer in patients with suspected prostate cancer using TRUS guided systematic biopsies as reference standard. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

By the author/editor: Blomqvist, L.; Carlsson, S.; Gjertsson, P.; Heintz, E.; Hultcrantz, M.; Mejare, I.; show more...; Andrén, Ove, 196 ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Radiology Nuclea ...

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