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Insertion sequence ...
Insertion sequence transpositions and point mutations in mgrB causing colistin resistance in a clinical strain of carbapenem-resistant Klebsiella pneumoniae from Vietnam
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- Berglund, Björn (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten
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- Bich Hoang, Ngoc Thi (author)
- Vietnam Natl Childrens Hosp, Vietnam
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- Tärnberg, Maria (author)
- Linköpings universitet,Avdelningen för neuro- och inflammationsvetenskap,Medicinska fakulteten
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- Kien Le, Ngai (author)
- Vietnam Natl Childrens Hosp, Vietnam
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- Svartström, Olov (author)
- Linköpings universitet,Institutionen för klinisk och experimentell medicin,Medicinska fakulteten,Region Östergötland, Klinisk mikrobiologi
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- Khanh Khu, Dung Thi (author)
- Vietnam Natl Childrens Hosp, Vietnam
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- Nilsson, Maud (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten
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- Thanh Le, Hai (author)
- Vietnam Natl Childrens Hosp, Vietnam
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- Welander, Jenny (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten,Region Östergötland, Klinisk mikrobiologi
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- Olson, Linus (author)
- Karolinska Institutet,TRAC, Sweden; TRAC, Vietnam; Karolinska Inst, Sweden
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- Larsson, Mattias (author)
- Karolinska Institutet,TRAC, Sweden; TRAC, Vietnam; Karolinska Inst, Sweden
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- Nilsson, Lennart E (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten
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- Hanberger, Håkan (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten,Region Östergötland, Infektionskliniken i Östergötland,TRAC, Sweden; TRAC, Vietnam
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(creator_code:org_t)
- ELSEVIER SCIENCE BV, 2018
- 2018
- English.
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In: International Journal of Antimicrobial Agents. - : ELSEVIER SCIENCE BV. - 0924-8579 .- 1872-7913. ; 51:5, s. 789-793
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Subject headings
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- Resistance among Klebsiella pneumoniae to the last-resort antibiotics carbapenems and colistin is increasing worldwide. In this study, whole-genome sequencing was used to determine the colistin resistance mechanisms in clinical isolates of carbapenem-and colistin-resistant K. pneumoniae from Vietnam. Alterations in the regulatory gene mgrB, via mutations and insertion sequence transpositions, were found in 30 of 31 isolates, emphasising the importance of this resistance mechanism in colistin-resistant K. pneumoniae. (c) 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Keyword
- Antibiotic resistance; Colistin; Insertion sequence; Klebsiella; mgrB
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
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Berglund, Björn
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Bich Hoang, Ngoc ...
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Tärnberg, Maria
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Kien Le, Ngai
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Svartström, Olov
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Khanh Khu, Dung ...
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show more...
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Nilsson, Maud
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Thanh Le, Hai
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Welander, Jenny
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Olson, Linus
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Larsson, Mattias
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Nilsson, Lennart ...
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Hanberger, Håkan
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Infectious Medic ...
- Articles in the publication
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International Jo ...
- By the university
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Linköping University
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Karolinska Institutet