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Innovations in serum and urine markers in prostate cancer current European research in the P-Mark project

van Gils, M P M Q (author)
Stenman, U H (author)
Schalken, J A (author)
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Schroder, F H (author)
Luider, T M (author)
Lilja, Hans (author)
Lund University,Lunds universitet,Klinisk kemi, Malmö,Forskargrupper vid Lunds universitet,Clinical Chemistry, Malmö,Lund University Research Groups
Bjartell, Anders (author)
Lund University,Lunds universitet,Urologisk cancerforskning, Malmö,Forskargrupper vid Lunds universitet,Urological cancer, Malmö,Lund University Research Groups
Hamdy, F C (author)
Pettersson, K S I (author)
Bischoff, R (author)
Takalo, H (author)
Nilsson, O (author)
Mulders, P F A (author)
Bangma, C H (author)
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 (creator_code:org_t)
Elsevier BV, 2005
2005
English.
In: European Urology. - : Elsevier BV. - 1873-7560 .- 0302-2838. ; 48:6, s. 1031-1041
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • An overview is given of serum and urine prostate cancer markers that are currently under investigation and subsequently the P-Mark project is introduced. There are many markers showing promise to overcome the limitations of prostate specific antigen (PSA). Eventually, these markers should be able to increase the specificity in diagnosis, differentiate between harmless and aggressive disease and identify progression towards androgen independence at an early stage. In the P-Mark project, several recently developed, promising markers will be evaluated using clinically well-defined biorepositories. Following successful evaluation, these markers will be validated on a sample set derived from two large, European, prostate cancer studies and used for the identification of special risk groups in the general population. In addition, novel markers will be identified in the same biorepositories by different mass spectrometry techniques.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Urology and Nephrology (hsv//eng)

Keyword

Prostatic neoplasms
Tumor markers
Biological
Serum
Urine
Diagnosis
Prognosis

Publication and Content Type

art (subject category)
ref (subject category)

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