WFRF:(Blixt Jonas)
Sökning: WFRF:(Blixt Jonas) > Characterization of...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04511naa a2200505 4500 | |
| 001 | oai:DiVA.org:lnu-77490 | |
| 003 | SwePub | |
| 008 | 180831s2018 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:uu-362683 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-774902 URI |
| 024 | 7 | a https://doi.org/10.1038/s41598-018-29578-12 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3626832 URI |
| 040 | a (SwePub)lnud (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Eriksson, Peru Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi4 aut0 (Swepub:uu)perer797 |
| 245 | 1 0 | a Characterization of avian influenza virus attachment patterns to human and pig tissues |
| 264 | c 2018-08-15 | |
| 264 | 1 | b Nature Publishing Group,c 2018 |
| 338 | a print2 rdacarrier | |
| 500 | a De två första författarna delar förstaförfattarskapet. | |
| 520 | a Wild birds of Anseriformes and Charadriiformes are natural reservoirs of influenza A viruses (IAVs). Occasionally, IAVs transmit and adapt to mammalian hosts, and are maintained as epidemic strains in their new hosts. Viral adaptions to mammalian hosts include altered receptor preference of host epithelial sialylated oligosaccharides from terminal alpha 2,3-linked sialic acid (SA) towards alpha 2,6-linked SA. However, alpha 2,3-linked SA has been found in human respiratory tract epithelium, and human infections by avian IAVs (AIVs) have been reported. To further explore the attachment properties of AIVs, four AIVs of different subtypes were investigated on human and pig tissues using virus histochemistry. Additionally, glycan array analysis was performed for further characterization of IAVs' receptor structure tropism. Generally, AIV attachment was more abundant to human tissues than to pig tissues. The attachment pattern was very strong to human conjunctiva and upper respiratory tract, but variable to the lower respiratory tract. AIVs mainly attached to alpha 2,3-linked SA, but also to combinations of alpha 2,3-and alpha 2,6-linked SA. The low attachment of these AIV isolates to pig tissues, but high attachment to human tissues, addresses the question whether AIVs in general require passage through pigs to obtain adaptions towards mammalian receptor structures. | |
| 650 | 7 | a NATURVETENSKAPx Biologix Mikrobiologi0 (SwePub)106062 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Microbiology0 (SwePub)106062 hsv//eng |
| 653 | a Zoonotic Ecology | |
| 653 | a Zoonotisk ekologi | |
| 700 | 1 | a Lindskog, Ceciliau Uppsala universitet,Institutionen för immunologi, genetik och patologi,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:uu)cecli129 |
| 700 | 1 | a Engholm, Ebbeu Univ Copenhagen, Chem Biol, Dept Chem, DK-1871 Frederiksberg C, Denmark4 aut |
| 700 | 1 | a Blixt, Olau Univ Copenhagen, Chem Biol, Dept Chem, DK-1871 Frederiksberg C, Denmark4 aut |
| 700 | 1 | a Waldenström, Jonas,d 1975-u Linnéuniversitetet,Institutionen för biologi och miljö (BOM),Ctr Ecol & Evolut Microbial Model Syst EEMiS,Linnaeus Univ, Ctr Ecol & Evolut Microbial Model Syst, SE-39231 Kalmar, Sweden4 aut0 (Swepub:lnu)ewajo |
| 700 | 1 | a Munster, Vincentu NIAID, Lab Virol, Rocky Mt Labs, NIH, Hamilton, MT 59840 USA4 aut |
| 700 | 1 | a Lundkvist, Åkeu Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi4 aut0 (Swepub:uu)akelu185 |
| 700 | 1 | a Olsen, Björnu Uppsala University, Sweden,Uppsala Univ, Zoonosis Sci Ctr, Dept Med Sci, SE-75123 Uppsala, Sweden4 aut |
| 700 | 1 | a Jourdain, Elsau INRA, EPIA, VetAgro Sup, UMR0346, FR-63122 St Genes Champanelle, France4 aut |
| 700 | 1 | a Ellström, Patriku Uppsala University, Sweden,Uppsala Univ, Zoonosis Sci Ctr, Dept Med Sci, SE-75123 Uppsala, Sweden4 aut |
| 710 | 2 | a Uppsala universitetb Institutionen för medicinsk biokemi och mikrobiologi4 org |
| 773 | 0 | t Scientific Reportsd : Nature Publishing Groupg 8q 8x 2045-2322 |
| 856 | 4 | u https://doi.org/10.1038/s41598-018-29578-1y Fulltext |
| 856 | 4 | u https://www.nature.com/articles/s41598-018-29578-1.pdf |
| 856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1262712/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-77490 |
| 856 | 4 8 | u https://doi.org/10.1038/s41598-018-29578-1 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-362683 |
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