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WFRF:(Dolores Chirlaque López María)
 

Sökning: WFRF:(Dolores Chirlaque López María) > Healthy lifestyle a...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008364naa a2201009 4500
001oai:lup.lub.lu.se:7f473c44-2c9b-4e11-8122-21d7e1a75c85
003SwePub
008191106s2020 | |||||||||||000 ||eng|
009oai:DiVA.org:umu-176113
0247 a https://lup.lub.lu.se/record/7f473c44-2c9b-4e11-8122-21d7e1a75c852 URI
0247 a https://doi.org/10.1007/s10654-019-00559-62 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1761132 URI
040 a (SwePub)lud (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Naudin, Sabineu International Agency for Research on Cancer, World Health Organization4 aut
2451 0a Healthy lifestyle and the risk of pancreatic cancer in the EPIC study
264 c 2019-09-28
264 1b Springer Science and Business Media LLC,c 2020
300 a 12 s.
520 a Pancreatic cancer (PC) is a highly fatal cancer with currently limited opportunities for early detection and effective treatment. Modifiable factors may offer pathways for primary prevention. In this study, the association between the Healthy Lifestyle Index (HLI) and PC risk was examined. Within the European Prospective Investigation into Cancer and Nutrition cohort, 1113 incident PC (57% women) were diagnosed from 400,577 participants followed-up for 15 years (median). HLI scores combined smoking, alcohol intake, dietary exposure, physical activity and, in turn, overall and central adiposity using BMI (HLIBMI) and waist-to-hip ratio (WHR, HLIWHR), respectively. High values of HLI indicate adherence to healthy behaviors. Cox proportional hazard models with age as primary time variable were used to estimate PC hazard ratios (HR) and 95% confidence intervals (CI). Sensitivity analyses were performed by excluding, in turn, each factor from the HLI score. Population attributable fractions (PAF) were estimated assuming participants’ shift to healthier lifestyles. The HRs for a one-standard deviation increment of HLIBMI and HLIWHR were 0.84 (95% CI: 0.79, 0.89; ptrend = 4.3e−09) and 0.77 (0.72, 0.82; ptrend = 1.7e−15), respectively. Exclusions of smoking from HLIWHR resulted in HRs of 0.88 (0.82, 0.94; ptrend = 4.9e−04). The overall PAF estimate was 19% (95% CI: 11%, 26%), and 14% (6%, 21%) when smoking was removed from the score. Adherence to a healthy lifestyle was inversely associated with PC risk, beyond the beneficial role of smoking avoidance. Public health measures targeting compliance with healthy lifestyles may have an impact on PC incidence.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
653 a EPIC
653 a Healthy Lifestyle Index
653 a Pancreatic cancer
653 a Population attributable fraction
653 a Prospective study
653 a Pancreatic cancer
7001 a Viallon, Vivianu International Agency for Research on Cancer, World Health Organization4 aut
7001 a Hashim, Danau Icahn School of Medicine at Mount Sinai4 aut
7001 a Freisling, Heinzu International Agency for Research on Cancer, World Health Organization4 aut
7001 a Jenab, Mazdau International Agency for Research on Cancer, World Health Organization4 aut
7001 a Weiderpass, Elisabeteu International Agency for Research on Cancer, World Health Organization4 aut
7001 a Perrier, Flavieu International Agency for Research on Cancer, World Health Organization4 aut
7001 a McKenzie, Fionau International Agency for Research on Cancer, World Health Organization4 aut
7001 a Bueno-de-Mesquita, H. Basu National Institute for Public Health and the Environment (RIVM),Imperial College London,University Medical Center Utrecht4 aut
7001 a Olsen, Anjau Danish Cancer Society4 aut
7001 a Tjønneland, Anneu University of Copenhagen,Danish Cancer Society4 aut
7001 a Dahm, Christina C.u Aarhus University4 aut
7001 a Overvad, Kimu Aalborg University,Aarhus University4 aut
7001 a Mancini, Francesca R.u Institut Gustave Roussy4 aut
7001 a Rebours, Vincianeu Beaujon Hospital,Paris Diderot University4 aut
7001 a Boutron-Ruault, Marie Christineu Institut Gustave Roussy4 aut
7001 a Katzke, Verenau German Cancer Research Centre4 aut
7001 a Kaaks, Rudolfu German Cancer Research Centre4 aut
7001 a Bergmann, Manuelau German Institute of Human Nutrition4 aut
7001 a Boeing, Heineru German Institute of Human Nutrition4 aut
7001 a Peppa, Eleniu Hellenic Health Foundation, Athens4 aut
7001 a Karakatsani, Annau National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens4 aut
7001 a Trichopoulou, Antoniau National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens4 aut
7001 a Pala, Valeriau Istituto Nazionale dei Tumori4 aut
7001 a Masala, Giovanau Institute for Cancer Research, Prevention and Clinical Network (ISPRO)4 aut
7001 a Panico, Salvatoreu University of Naples Federico II4 aut
7001 a Tumino, Rosariou Civic and M.P Arezzo Hospital4 aut
7001 a Sacerdote, Carlottau Citta' della Salute e della Scienza Hospital-University of Turin4 aut
7001 a May, Anne M.u University Medical Center Utrecht4 aut
7001 a van Gils, Carla H.u University Medical Center Utrecht4 aut
7001 a Rylander, Charlottau UiT The Arctic University of Norway, Tromsø4 aut
7001 a Borch, Kristin Benjaminsenu UiT The Arctic University of Norway, Tromsø4 aut
7001 a Chirlaque López, María Doloresu University of Murcia4 aut
7001 a Sánchez, Maria Joseu University of Granada4 aut
7001 a Ardanaz, Evau Health Research Institute of Navarra (IDISNA),CIBER Epidemiology and Public Health (CIBERESP),Navarre Public Health Institute (ISPN)4 aut0 (Swepub:lu)extLU-05
7001 a Quirós, José Ramónu Public Health Directorate4 aut
7001 a Amiano Exezarreta, Pilar4 aut
7001 a Sund, Malinu Umeå universitet,Umeå University,Kirurgi4 aut0 (Swepub:umu)masu0021
7001 a Drake, Isabelu Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups4 aut0 (Swepub:lu)med-ihm
7001 a Regnér, Sarau Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)kir-sre
7001 a Travis, Ruth C.u University of Oxford4 aut
7001 a Wareham, Nicku University of Cambridge4 aut
7001 a Aune, Dagfinnu Oslo university hospital,Bjørknes University College,Imperial College London4 aut
7001 a Riboli, Eliou Imperial College London4 aut
7001 a Gunter, Marc J.u International Agency for Research on Cancer, World Health Organization4 aut
7001 a Duell, Eric J.u Catalan Institute of Oncology4 aut
7001 a Brennan, Paulu International Agency for Research on Cancer, World Health Organization4 aut
7001 a Ferrari, Pietrou International Agency for Research on Cancer, World Health Organization4 aut
7102 a International Agency for Research on Cancer, World Health Organizationb Icahn School of Medicine at Mount Sinai4 org
7730 t European Journal of Epidemiologyd : Springer Science and Business Media LLCg 35:10, s. 975-986q 35:10<975-986x 0393-2990x 1573-7284
8564 u http://dx.doi.org/10.1007/s10654-019-00559-6y FULLTEXT
8564 u https://munin.uit.no/bitstream/10037/18029/4/article.pdf
8564 8u https://lup.lub.lu.se/record/7f473c44-2c9b-4e11-8122-21d7e1a75c85
8564 8u https://doi.org/10.1007/s10654-019-00559-6
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-176113

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