Sökning: WFRF:(Dolores Chirlaque López María) > Healthy lifestyle a...
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000 | 08364naa a2201009 4500 | |
001 | oai:lup.lub.lu.se:7f473c44-2c9b-4e11-8122-21d7e1a75c85 | |
003 | SwePub | |
008 | 191106s2020 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-176113 | |
024 | 7 | a https://lup.lub.lu.se/record/7f473c44-2c9b-4e11-8122-21d7e1a75c852 URI |
024 | 7 | a https://doi.org/10.1007/s10654-019-00559-62 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1761132 URI |
040 | a (SwePub)lud (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Naudin, Sabineu International Agency for Research on Cancer, World Health Organization4 aut |
245 | 1 0 | a Healthy lifestyle and the risk of pancreatic cancer in the EPIC study |
264 | c 2019-09-28 | |
264 | 1 | b Springer Science and Business Media LLC,c 2020 |
300 | a 12 s. | |
520 | a Pancreatic cancer (PC) is a highly fatal cancer with currently limited opportunities for early detection and effective treatment. Modifiable factors may offer pathways for primary prevention. In this study, the association between the Healthy Lifestyle Index (HLI) and PC risk was examined. Within the European Prospective Investigation into Cancer and Nutrition cohort, 1113 incident PC (57% women) were diagnosed from 400,577 participants followed-up for 15 years (median). HLI scores combined smoking, alcohol intake, dietary exposure, physical activity and, in turn, overall and central adiposity using BMI (HLIBMI) and waist-to-hip ratio (WHR, HLIWHR), respectively. High values of HLI indicate adherence to healthy behaviors. Cox proportional hazard models with age as primary time variable were used to estimate PC hazard ratios (HR) and 95% confidence intervals (CI). Sensitivity analyses were performed by excluding, in turn, each factor from the HLI score. Population attributable fractions (PAF) were estimated assuming participants’ shift to healthier lifestyles. The HRs for a one-standard deviation increment of HLIBMI and HLIWHR were 0.84 (95% CI: 0.79, 0.89; ptrend = 4.3e−09) and 0.77 (0.72, 0.82; ptrend = 1.7e−15), respectively. Exclusions of smoking from HLIWHR resulted in HRs of 0.88 (0.82, 0.94; ptrend = 4.9e−04). The overall PAF estimate was 19% (95% CI: 11%, 26%), and 14% (6%, 21%) when smoking was removed from the score. Adherence to a healthy lifestyle was inversely associated with PC risk, beyond the beneficial role of smoking avoidance. Public health measures targeting compliance with healthy lifestyles may have an impact on PC incidence. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
653 | a EPIC | |
653 | a Healthy Lifestyle Index | |
653 | a Pancreatic cancer | |
653 | a Population attributable fraction | |
653 | a Prospective study | |
653 | a Pancreatic cancer | |
700 | 1 | a Viallon, Vivianu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Hashim, Danau Icahn School of Medicine at Mount Sinai4 aut |
700 | 1 | a Freisling, Heinzu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Jenab, Mazdau International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Weiderpass, Elisabeteu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Perrier, Flavieu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a McKenzie, Fionau International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Bueno-de-Mesquita, H. Basu National Institute for Public Health and the Environment (RIVM),Imperial College London,University Medical Center Utrecht4 aut |
700 | 1 | a Olsen, Anjau Danish Cancer Society4 aut |
700 | 1 | a Tjønneland, Anneu University of Copenhagen,Danish Cancer Society4 aut |
700 | 1 | a Dahm, Christina C.u Aarhus University4 aut |
700 | 1 | a Overvad, Kimu Aalborg University,Aarhus University4 aut |
700 | 1 | a Mancini, Francesca R.u Institut Gustave Roussy4 aut |
700 | 1 | a Rebours, Vincianeu Beaujon Hospital,Paris Diderot University4 aut |
700 | 1 | a Boutron-Ruault, Marie Christineu Institut Gustave Roussy4 aut |
700 | 1 | a Katzke, Verenau German Cancer Research Centre4 aut |
700 | 1 | a Kaaks, Rudolfu German Cancer Research Centre4 aut |
700 | 1 | a Bergmann, Manuelau German Institute of Human Nutrition4 aut |
700 | 1 | a Boeing, Heineru German Institute of Human Nutrition4 aut |
700 | 1 | a Peppa, Eleniu Hellenic Health Foundation, Athens4 aut |
700 | 1 | a Karakatsani, Annau National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens4 aut |
700 | 1 | a Trichopoulou, Antoniau National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens4 aut |
700 | 1 | a Pala, Valeriau Istituto Nazionale dei Tumori4 aut |
700 | 1 | a Masala, Giovanau Institute for Cancer Research, Prevention and Clinical Network (ISPRO)4 aut |
700 | 1 | a Panico, Salvatoreu University of Naples Federico II4 aut |
700 | 1 | a Tumino, Rosariou Civic and M.P Arezzo Hospital4 aut |
700 | 1 | a Sacerdote, Carlottau Citta' della Salute e della Scienza Hospital-University of Turin4 aut |
700 | 1 | a May, Anne M.u University Medical Center Utrecht4 aut |
700 | 1 | a van Gils, Carla H.u University Medical Center Utrecht4 aut |
700 | 1 | a Rylander, Charlottau UiT The Arctic University of Norway, Tromsø4 aut |
700 | 1 | a Borch, Kristin Benjaminsenu UiT The Arctic University of Norway, Tromsø4 aut |
700 | 1 | a Chirlaque López, María Doloresu University of Murcia4 aut |
700 | 1 | a Sánchez, Maria Joseu University of Granada4 aut |
700 | 1 | a Ardanaz, Evau Health Research Institute of Navarra (IDISNA),CIBER Epidemiology and Public Health (CIBERESP),Navarre Public Health Institute (ISPN)4 aut0 (Swepub:lu)extLU-05 |
700 | 1 | a Quirós, José Ramónu Public Health Directorate4 aut |
700 | 1 | a Amiano Exezarreta, Pilar4 aut |
700 | 1 | a Sund, Malinu Umeå universitet,Umeå University,Kirurgi4 aut0 (Swepub:umu)masu0021 |
700 | 1 | a Drake, Isabelu Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups4 aut0 (Swepub:lu)med-ihm |
700 | 1 | a Regnér, Sarau Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)kir-sre |
700 | 1 | a Travis, Ruth C.u University of Oxford4 aut |
700 | 1 | a Wareham, Nicku University of Cambridge4 aut |
700 | 1 | a Aune, Dagfinnu Oslo university hospital,Bjørknes University College,Imperial College London4 aut |
700 | 1 | a Riboli, Eliou Imperial College London4 aut |
700 | 1 | a Gunter, Marc J.u International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Duell, Eric J.u Catalan Institute of Oncology4 aut |
700 | 1 | a Brennan, Paulu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Ferrari, Pietrou International Agency for Research on Cancer, World Health Organization4 aut |
710 | 2 | a International Agency for Research on Cancer, World Health Organizationb Icahn School of Medicine at Mount Sinai4 org |
773 | 0 | t European Journal of Epidemiologyd : Springer Science and Business Media LLCg 35:10, s. 975-986q 35:10<975-986x 0393-2990x 1573-7284 |
856 | 4 | u http://dx.doi.org/10.1007/s10654-019-00559-6y FULLTEXT |
856 | 4 | u https://munin.uit.no/bitstream/10037/18029/4/article.pdf |
856 | 4 8 | u https://lup.lub.lu.se/record/7f473c44-2c9b-4e11-8122-21d7e1a75c85 |
856 | 4 8 | u https://doi.org/10.1007/s10654-019-00559-6 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-176113 |
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