Search: WFRF:(Ernstgård Lena) >
Acute effects of 1-...
-
Wålinder, RobertUppsala universitet,Institutionen för medicinska vetenskaper,Eva Vingård
(author)
Acute effects of 1-octen-3-ol, a microbial volatile organic compound (MVOC)--an experimental study
- Article/chapterEnglish2008
Publisher, publication year, extent ...
-
Elsevier BV,2008
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:uu-88274
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-88274URI
-
https://doi.org/10.1016/j.toxlet.2008.07.013DOI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:117785366URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Acute effects were assessed from exposure to a common volatile compound of microbial origin, the aliphatic alcohol 1-octen 3-ol (octenol). Twenty-nine volunteers performed symptom reports, measurement of blink frequency by electromyography, measurement of the eye break-up time, vital staining of the eye, nasal lavage, acoustic rhinometry, transfer tests and dynamic spirometry. Subjects were during 2h in random order exposed to either 10mg/m(3) of octenol or clean air as control. During octenol exposure subjective ratings of smell and nasal irritation were increased together with higher nasal lavage biomarker levels of eosinophil cationic protein, myeloperoxidase and lysozyme. Also eye irritation and blinking frequency were increased together with throat irritation, mild dyspnoea after 1-h but not after 2-h, and a small decrease in vital capacity. Ratings of headache and nausea were also increased. Atopics did not have more reactions due to exposure, whereas females experienced more smell and mucosal irritation. Thus, there were both subjective and objective signs of mild mucosal irritation of eyes and airways together with symptoms of headache and nausea.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Ernstgård, LenaKarolinska Institutet
(author)
-
Norbäck, DanUppsala universitet,Institutionen för medicinska vetenskaper,Eva Vingård(Swepub:uu)dagnorba
(author)
-
Wieslander, GunillaUppsala universitet,Institutionen för medicinska vetenskaper,Eva Vingård
(author)
-
Johanson, GunnarKarolinska Institutet
(author)
-
Uppsala universitetInstitutionen för medicinska vetenskaper
(creator_code:org_t)
Related titles
-
In:Toxicology Letters: Elsevier BV181:3, s. 141-70378-42741879-3169
Internet link
Find in a library
To the university's database