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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003476naa a2200505 4500
001oai:DiVA.org:umu-32335
003SwePub
008100310s2009 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-323352 URI
0247 a https://doi.org/10.1038/oby.2009.732 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Goedecke, Julia H4 aut
2451 0a Differential effects of abdominal adipose tissue distribution on insulin sensitivity in black and white South African women
264 c 2012-09-06
264 1b Wiley,c 2009
338 a print2 rdacarrier
520 a Black South African women are more insulin resistant than BMI-matched white women. The objective of the study was to characterize the determinants of insulin sensitivity in black and white South African women matched for BMI. A total of 57 normal-weight (BMI 18-25 kg/m(2)) and obese (BMI > 30 kg/m(2)) black and white premenopausal South African women underwent the following measurements: body composition (dual-energy X-ray absorptiometry), body fat distribution (computerized tomography (CT)), insulin sensitivity (S(I), frequently sampled intravenous glucose tolerance test), dietary intake (food frequency questionnaire), physical activity (Global Physical Activity Questionnaire), and socioeconomic status (SES, demographic questionnaire). Black women were less insulin sensitive (4.4 +/- 0.8 vs. 9.5 +/- 0.8 and 3.0 +/- 0.8 vs. 6.0 +/- 0.8 x 10(-5)/min/(pmol/l), for normal-weight and obese women, respectively, P < 0.001), but had less visceral adipose tissue (VAT) (P = 0.051), more abdominal superficial subcutaneous adipose tissue (SAT) (P = 0.003), lower SES (P < 0.001), and higher dietary fat intake (P = 0.001) than white women matched for BMI. S(I) correlated with deep and superficial SAT in both black (R = -0.594, P = 0.002 and R = 0.495, P = 0.012) and white women (R = -0.554, P = 0.005 and R = -0.546, P = 0.004), but with VAT in white women only (R = -0.534, P = 0.005). In conclusion, body fat distribution is differentially associated with insulin sensitivity in black and white women. Therefore, the different abdominal fat depots may have varying metabolic consequences in women of different ethnic origins.
653 a apoptosis
653 a cisplatin
653 a malignant pleural mesothelioma (MPM)
653 a phase-contrast microscopy (PCM)
653 a scanning electron microscopy (SEM)
653 a MEDICINE
653 a MEDICIN
7001 a Levitt, Naomi S4 aut
7001 a Lambert, Estelle V4 aut
7001 a Utzschneider, Kristina M4 aut
7001 a Faulenbach, Mirjam V4 aut
7001 a Dave, Joel A4 aut
7001 a West, Sacha4 aut
7001 a Victor, Hendriena4 aut
7001 a Evans, Julietu Umeå universitet,Medicin4 aut
7001 a Olsson, Tommyu Umeå universitet,Medicin4 aut0 (Swepub:umu)tool0003
7001 a Walker, Brian R4 aut
7001 a Seckl, Jonathan R4 aut
7001 a Kahn, Steven E4 aut
7102 a Umeå universitetb Medicin4 org
7730 t Obesityd : Wileyg 17:8, s. 1506-1512q 17:8<1506-1512x 1930-7381x 1930-739X
8564 u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1038/oby.2009.73
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-32335
8564 8u https://doi.org/10.1038/oby.2009.73

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