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Sökning: WFRF:(Gad A) > (1995-1999) > Mechanism of contra...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002515naa a2200313 4500
001oai:prod.swepub.kib.ki.se:1927422
003SwePub
008240811s1998 | |||||||||||000 ||eng|
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:19274222 URI
024a https://doi.org/10.1080/028418598091722142 DOI
040 a (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Bone, Bu Karolinska Institutet4 aut
2451 0a Mechanism of contrast enhancement in breast lesions at MR imaging
264 c 2016-08-30
264 1b SAGE Publications,c 1998
520 a Purpose: the aim of the study was to explain why breast lesions are enhanced by contrast medium at MR imaging and to elucidate the histopathological basis for the overlap in the enhancement patterns of benign and malignant breast lesions Material and Methods: Ten invasive breast carcinomas and 10 benign breast lesions were selected for the study. of the 10 carcinomas, 5 showed a strong and early contrast enhancement, and 5 did not. of the 10 benign lesions, 5 showed a strong and early contrast enhancement, and 5 showed no enhancement. the following morphometric variables were evaluated: proliferation cell index of neoplastic parenchymal cells, S-phase fraction, nuclear ploidy analysed by image DNA-cytometry, microvessel density, and the percentage proportion of the interstitial area Results: Contrast enhancement was related to the proliferating activity of the hyperplastic or neoplastic parenchymal cells and was inversely correlated with the interstitial area in carcinomas as well as in benign tumours and non-neo-plastic lesions of the breast Conclusion: Morphometric variables play an important role in the general mechanism of MR contrast enhancement in examinations of the breast and explain the histopathological basis for the overlap in the enhancement patterns of benign and malignant breast lesions
700a Wiberg, MKu Karolinska Institutet4 aut
700a Parrado, C4 aut
700a Falkmer, U4 aut
700a Aspelin, Pu Karolinska Institutet4 aut
700a Gad, A4 aut
710a Karolinska Institutet4 org
773t Acta radiologica (Stockholm, Sweden : 1987)d : SAGE Publicationsg 39:5, s. 494-500q 39:5<494-500x 0284-1851x 1600-0455
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:1927422
8564 8u https://doi.org/10.1080/02841859809172214

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Bone, B
Wiberg, MK
Parrado, C
Falkmer, U
Aspelin, P
Gad, A
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Acta radiologica ...
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Karolinska Institutet

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