Sökning: WFRF:(Gad A) > (1995-1999) > Mechanism of contra...
Fältnamn | Indikatorer | Metadata |
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000 | 02515naa a2200313 4500 | |
001 | oai:prod.swepub.kib.ki.se:1927422 | |
003 | SwePub | |
008 | 240811s1998 | |||||||||||000 ||eng| | |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19274222 URI |
024 | 7 | a https://doi.org/10.1080/028418598091722142 DOI |
040 | a (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Bone, Bu Karolinska Institutet4 aut |
245 | 1 0 | a Mechanism of contrast enhancement in breast lesions at MR imaging |
264 | c 2016-08-30 | |
264 | 1 | b SAGE Publications,c 1998 |
520 | a Purpose: the aim of the study was to explain why breast lesions are enhanced by contrast medium at MR imaging and to elucidate the histopathological basis for the overlap in the enhancement patterns of benign and malignant breast lesions Material and Methods: Ten invasive breast carcinomas and 10 benign breast lesions were selected for the study. of the 10 carcinomas, 5 showed a strong and early contrast enhancement, and 5 did not. of the 10 benign lesions, 5 showed a strong and early contrast enhancement, and 5 showed no enhancement. the following morphometric variables were evaluated: proliferation cell index of neoplastic parenchymal cells, S-phase fraction, nuclear ploidy analysed by image DNA-cytometry, microvessel density, and the percentage proportion of the interstitial area Results: Contrast enhancement was related to the proliferating activity of the hyperplastic or neoplastic parenchymal cells and was inversely correlated with the interstitial area in carcinomas as well as in benign tumours and non-neo-plastic lesions of the breast Conclusion: Morphometric variables play an important role in the general mechanism of MR contrast enhancement in examinations of the breast and explain the histopathological basis for the overlap in the enhancement patterns of benign and malignant breast lesions | |
700 | 1 | a Wiberg, MKu Karolinska Institutet4 aut |
700 | 1 | a Parrado, C4 aut |
700 | 1 | a Falkmer, U4 aut |
700 | 1 | a Aspelin, Pu Karolinska Institutet4 aut |
700 | 1 | a Gad, A4 aut |
710 | 2 | a Karolinska Institutet4 org |
773 | 0 | t Acta radiologica (Stockholm, Sweden : 1987)d : SAGE Publicationsg 39:5, s. 494-500q 39:5<494-500x 0284-1851x 1600-0455 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1927422 |
856 | 4 8 | u https://doi.org/10.1080/02841859809172214 |
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