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Regional difference...
Regional differences in precipitating factors of hospitalization for acute heart failure: insights from the REPORT-HF registry
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- Tromp, Jasper (författare)
- Natl Univ Singapore, Singapore; Natl Univ Hlth Syst, Singapore; Duke NUS Med Sch, Singapore
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- Beusekamp, Joost C. (författare)
- Univ Groningen, Netherlands
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- Ouwerkerk, Wouter (författare)
- Natl Heart Ctr Singapore, Singapore; Univ Amsterdam, Netherlands
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- van der Meer, Peter (författare)
- Univ Groningen, Netherlands
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- Cleland, John G. F. (författare)
- Univ Glasgow, England; Imperial Coll, England
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- Angermann, Christiane E. (författare)
- Univ Hosp, Germany; Univ Wurzburg, Germany
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- Dahlström, Ulf (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
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- Ertl, Georg (författare)
- Univ Hosp, Germany; Univ Wurzburg, Germany
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- Hassanein, Mahmoud (författare)
- Alexandria Univ, Egypt
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- Perrone, Sergio V (författare)
- El Cruce Hosp Florencio Varela, Argentina
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- Ghadanfar, Mathieu (författare)
- M Ghadanfar Consulting Life Sci, Switzerland
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- Schweizer, Anja (författare)
- Novartis Pharma AG, Switzerland
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- Obergfell, Achim (författare)
- Novartis Pharma AG, Switzerland
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- Filippatos, Gerasimos (författare)
- Univ Cyprus, Greece; Natl & Kapodistrian Univ Athens, Greece
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- Dickstein, Kenneth (författare)
- Univ Bergen, Norway
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- Collins, Sean P. (författare)
- Vanderbilt Univ, TN USA; Vet Affairs Tennessee Valley Healthcare Syst, TN USA
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- Lam, Carolyn S. P. (författare)
- Duke NUS Med Sch, Singapore; Univ Groningen, Netherlands; Natl Heart Ctr Singapore, Singapore
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(creator_code:org_t)
- 2022-02-17
- 2022
- Engelska.
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Ingår i: European Journal of Heart Failure. - : WILEY. - 1388-9842 .- 1879-0844. ; 24:4, s. 645-652
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Aims Few prior studies have investigated differences in precipitants leading to hospitalizations for acute heart failure (AHF) in a cohort with global representation. Methods and results We analysed the prevalence of precipitants and their association with outcomes in 18 553 patients hospitalized for AHF in REPORT-HF (prospective international REgistry to assess medical Practice with lOngitudinal obseRvation for Treatment of Heart Failure) according to left ventricular ejection fraction subtype (reduced [HFrEF] and preserved ejection fraction [HFpEF]) and presentation (new-onset vs. decompensated chronic heart failure [DCHF]). Patients were enrolled from 358 centres in 44 countries stratified according to Latin America, North America, Western Europe, Eastern Europe, Eastern Mediterranean and Africa, Southeast Asia, and Western Pacific. Precipitants were pre-with mutually exclusive categories and selected according to the local investigators discretion. Outcomes included in-hospital and 1-year mortality. The median age was 67 (interquartile range 57-77) years, and 39% were women. Acute coronary syndrome (ACS) was the most common precipitant in patients with new-onset heart failure in all regions except for North America and Western Europe, where uncontrolled hypertension and arrhythmia, respectively, were the most common precipitants, independent of confounders. In patients with DCHF, non-adherence to diet/medication was the most common precipitant regardless of region. Uncontrolled hypertension was a more likely precipitant in HFpEF, non-adherence to diet/medication, and ACS were more likely precipitants in HFrEF. Patients admitted due to worsening renal function had the worst in-hospital (5%) and 1-year post-discharge (30%) mortality rates, regardless of region, heart failure subtype and admission type (p(interaction) >0.05 for all). Conclusion Data on global differences in precipitants for AHF highlight potential regional differences in targets for preventing hospitalization for AHF and identifying those at highest risk for early mortality.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Precipitants; Heart failure; Acute heart failure; HFrEF; HFpEF; Global differences
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Tromp, Jasper
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Beusekamp, Joost ...
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Ouwerkerk, Woute ...
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van der Meer, Pe ...
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Cleland, John G. ...
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Angermann, Chris ...
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visa fler...
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Dahlström, Ulf
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Ertl, Georg
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Hassanein, Mahmo ...
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Perrone, Sergio ...
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Ghadanfar, Mathi ...
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Schweizer, Anja
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Obergfell, Achim
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Filippatos, Gera ...
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Dickstein, Kenne ...
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Collins, Sean P.
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Lam, Carolyn S. ...
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