WFRF:(Herbst E.)
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COMPRES : a prospective postmarketing evaluation of the compression anastomosis ring CAR 27/ColonRing
- D'Hoore, A. (author)
- Albert, M. R. (author)
- Cohen, S. M. (author)
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- Herbst, F. (author)
- Matter, I. (author)
- Van der Speeten, K. (author)
- Dominguez, J. (author)
- Rutten, H. (author)
- Muldoon, J. P. (author)
- Bardakcioglu, O. (author)
- Senagore, A. J. (author)
- Ruppert, R. (author)
- Mills, S. (author)
- Stamos, M. J. (author)
- Choman, E. (author)
- Wexner, S. D. (author)
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- (creator_code:org_t)
- 2015-05-20
- 2015
- English.
- In: Colorectal Disease. - : Wiley. - 1462-8910 .- 1463-1318. ; 17:6, s. 522-529
- Journal article (peer-reviewed)
Abstract
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- AimPreclinical studies have suggested that nitinol-based compression anastomosis might be a viable solution to anastomotic leak following low anterior resection. A prospective multicentre open label study was therefore designed to evaluate the performance of the ColonRing in (low) colorectal anastomosis. MethodThe primary outcome measure was anastomotic leakage. Patients were recruited at 13 different colorectal surgical units in Europe, the United States and Israel. Institutional review board approval was obtained. ResultsBetween 21 March 2010 and 3 August 2011, 266 patients completed the study protocol. The overall anastomotic leakage rate was 5.3% for all anastomoses, including a rate of 3.1% for low anastomoses. Septic anastomotic complications occurred in 8.3% of all anastomoses and 8.2% of low anastomoses. ConclusionNitinol compression anastomosis is safe, effective and easy to use and may offer an advantage for low colorectal anastomosis. A prospective randomized trial comparing ColonRing with conventional stapling is needed.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Keyword
- Compression anastomosis
- anastomotic leakage
- low anterior resection
Publication and Content Type
- ref (subject category)
- art (subject category)
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- D'Hoore, A.
- Albert, M. R.
- Cohen, S. M.
- Herbst, F.
- Matter, I.
- Van der Speeten, ...
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- Dominguez, J.
- Rutten, H.
- Muldoon, J. P.
- Bardakcioglu, O.
- Senagore, A. J.
- Ruppert, R.
- Mills, S.
- Stamos, M. J.
- Påhlman, Lars
- Choman, E.
- Wexner, S. D.
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- MEDICAL AND HEALTH SCIENCES
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- Colorectal Disea ...
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- Uppsala University
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