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Genome sequence of Aedes aegypti, a major arbovirus vector.

Nene, Vishvanath (author)
Wortman, Jennifer R (author)
Lawson, Daniel (author)
show more...
Haas, Brian (author)
Kodira, Chinnappa (author)
Tu, Zhijian Jake (author)
Loftus, Brendan (author)
Xi, Zhiyong (author)
Megy, Karyn (author)
Grabherr, Manfred (author)
Ren, Quinghu (author)
Zdobnov, Evgeny M (author)
Lobo, Neil F (author)
Campbell, Kathryn S (author)
Brown, Susan E (author)
Bonaldo, Maria F (author)
Zhu, Jingsong (author)
Sinkins, Steven P (author)
Hogenkamp, David G (author)
Amedeo, Paolo (author)
Arensburger, Peter (author)
Atkinson, Peter W (author)
Bidwell, Shelby (author)
Biedler, Jim (author)
Birney, Ewan (author)
Bruggner, Robert V (author)
Costas, Javier (author)
Coy, Monique R (author)
Crabtree, Jonathan (author)
Crawford, Matt (author)
Debruyn, Becky (author)
Decaprio, David (author)
Eiglmeier, Karin (author)
Eisenstadt, Eric (author)
El-Dorry, Hamza (author)
Gelbart, William M (author)
Gomes, Suely L (author)
Hammond, Martin (author)
Hannick, Linda I (author)
Hogan, James R (author)
Holmes, Michael H (author)
Jaffe, David (author)
Johnston, J Spencer (author)
Kennedy, Ryan C (author)
Koo, Hean (author)
Kravitz, Saul (author)
Kriventseva, Evgenia V (author)
Kulp, David (author)
Labutti, Kurt (author)
Lee, Eduardo (author)
Li, Song (author)
Lovin, Diane D (author)
Mao, Chunhong (author)
Mauceli, Evan (author)
Menck, Carlos F M (author)
Miller, Jason R (author)
Montgomery, Philip (author)
Mori, Akio (author)
Nascimento, Ana L (author)
Naveira, Horacio F (author)
Nusbaum, Chad (author)
O'leary, Sinéad (author)
Orvis, Joshua (author)
Pertea, Mihaela (author)
Quesneville, Hadi (author)
Reidenbach, Kyanne R (author)
Rogers, Yu-Hui (author)
Roth, Charles W (author)
Schneider, Jennifer R (author)
Schatz, Michael (author)
Shumway, Martin (author)
Stanke, Mario (author)
Stinson, Eric O (author)
Tubio, Jose M C (author)
Vanzee, Janice P (author)
Verjovski-Almeida, Sergio (author)
Werner, Doreen (author)
White, Owen (author)
Wyder, Stefan (author)
Zeng, Qiandong (author)
Zhao, Qi (author)
Zhao, Yongmei (author)
Hill, Catherine A (author)
Raikhel, Alexander S (author)
Soares, Marcelo B (author)
Knudson, Dennis L (author)
Lee, Norman H (author)
Galagan, James (author)
Salzberg, Steven L (author)
Paulsen, Ian T (author)
Dimopoulos, George (author)
Collins, Frank H (author)
Birren, Bruce (author)
Fraser-Liggett, Claire M (author)
Severson, David W (author)
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American Association for the Advancement of Science (AAAS), 2007
2007
English.
In: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 316:5832, s. 1718-23
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • We present a draft sequence of the genome of Aedes aegypti, the primary vector for yellow fever and dengue fever, which at approximately 1376 million base pairs is about 5 times the size of the genome of the malaria vector Anopheles gambiae. Nearly 50% of the Ae. aegypti genome consists of transposable elements. These contribute to a factor of approximately 4 to 6 increase in average gene length and in sizes of intergenic regions relative to An. gambiae and Drosophila melanogaster. Nonetheless, chromosomal synteny is generally maintained among all three insects, although conservation of orthologous gene order is higher (by a factor of approximately 2) between the mosquito species than between either of them and the fruit fly. An increase in genes encoding odorant binding, cytochrome P450, and cuticle domains relative to An. gambiae suggests that members of these protein families underpin some of the biological differences between the two mosquito species.

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By the author/editor
Nene, Vishvanath
Wortman, Jennife ...
Lawson, Daniel
Haas, Brian
Kodira, Chinnapp ...
Tu, Zhijian Jake
show more...
Loftus, Brendan
Xi, Zhiyong
Megy, Karyn
Grabherr, Manfre ...
Ren, Quinghu
Zdobnov, Evgeny ...
Lobo, Neil F
Campbell, Kathry ...
Brown, Susan E
Bonaldo, Maria F
Zhu, Jingsong
Sinkins, Steven ...
Hogenkamp, David ...
Amedeo, Paolo
Arensburger, Pet ...
Atkinson, Peter ...
Bidwell, Shelby
Biedler, Jim
Birney, Ewan
Bruggner, Robert ...
Costas, Javier
Coy, Monique R
Crabtree, Jonath ...
Crawford, Matt
Debruyn, Becky
Decaprio, David
Eiglmeier, Karin
Eisenstadt, Eric
El-Dorry, Hamza
Gelbart, William ...
Gomes, Suely L
Hammond, Martin
Hannick, Linda I
Hogan, James R
Holmes, Michael ...
Jaffe, David
Johnston, J Spen ...
Kennedy, Ryan C
Koo, Hean
Kravitz, Saul
Kriventseva, Evg ...
Kulp, David
Labutti, Kurt
Lee, Eduardo
Li, Song
Lovin, Diane D
Mao, Chunhong
Mauceli, Evan
Menck, Carlos F ...
Miller, Jason R
Montgomery, Phil ...
Mori, Akio
Nascimento, Ana ...
Naveira, Horacio ...
Nusbaum, Chad
O'leary, Sinéad
Orvis, Joshua
Pertea, Mihaela
Quesneville, Had ...
Reidenbach, Kyan ...
Rogers, Yu-Hui
Roth, Charles W
Schneider, Jenni ...
Schatz, Michael
Shumway, Martin
Stanke, Mario
Stinson, Eric O
Tubio, Jose M C
Vanzee, Janice P
Verjovski-Almeid ...
Werner, Doreen
White, Owen
Wyder, Stefan
Zeng, Qiandong
Zhao, Qi
Zhao, Yongmei
Hill, Catherine ...
Raikhel, Alexand ...
Soares, Marcelo ...
Knudson, Dennis ...
Lee, Norman H
Galagan, James
Salzberg, Steven ...
Paulsen, Ian T
Dimopoulos, Geor ...
Collins, Frank H
Birren, Bruce
Fraser-Liggett, ...
Severson, David ...
show less...
Articles in the publication
Science (New Yor ...
By the university
Uppsala University

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