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Sökning: WFRF:(Kamali A) > (2000-2004) > A community randomi...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003331naa a2200349 4500
001oai:DiVA.org:umu-52351
003SwePub
008120220s2002 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-523512 URI
0247 a https://doi.org/10.1046/j.1365-3156.2002.00963.x2 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Kamali, Anatoli4 aut
2451 0a A community randomized controlled trial to investigate impact of improved STD management and behavioural interventions on HIV incidence in rural Masaka, Uganda :b trial design, methods and baseline findings
264 1b Wiley,c 2002
338 a print2 rdacarrier
520 a OBJECTIVE: To describe study design, methods and baseline findings of a behavioural intervention alone and in combination with improved management of sexually transmitted diseases (STDs) aimed at reducing HIV incidence and other STDs. DESIGN: A three-arm community randomized controlled trial (RCT) of 18 rural communities (approximately 96 000 adults) in SW Uganda. A standardized behavioural intervention was implemented in 12 communities (arms A and B) through community-based education, meetings and information leaflets. Six of these communities in addition received improved STD management through government and private health units (arm B). Arm C communities received routine government health services. Impact assessment was through three questionnaire and serological surveys of 750-1000 adults in each community at 18-24-month intervals. The primary outcome measure was HIV incidence and secondary measures were syphilis and herpes simplex virus type 2 incidence, prevalence of Neisseria gonorrhoea and Chlamydia trachomatis and sexual behaviour changes. RESULTS: Approximately 15 000 adults (72% of eligible population) were enrolled at baseline. HIV baseline prevalence rates were 9-10% in all arms and demographic and behavioural characteristics and STD prevalence were also similar. In intervention communities, there were 391 995 attendance at 81 502 activities (6.1 per target adult), 164 063 leaflets distributed (2.6 per person) and 1 586 270 condoms (16.5 condoms per adult). In the STD communities a total of 12 239 STD cases (65% women) were seen over a 5-year period (7.7 per 100 adults/year). CONCLUSION: This is the first community RCT of its type with a behavioural component. There is fair baseline comparability between study arms and process data suggest that interventions were adequately implemented.
7001 a Kinsman, Johnu Medical Research Council Programme on AIDS, Uganda4 aut0 (Swepub:umu)joki0020
7001 a Nalweyiso, Norah4 aut
7001 a Mitchell, Kirstin4 aut
7001 a Kanyesigye, Edward4 aut
7001 a Kengeya-Kayondo, Jane F4 aut
7001 a Carpenter, Lucy M4 aut
7001 a Nunn, Andrew4 aut
7001 a Whitworth, James A G4 aut
7102 a Medical Research Council Programme on AIDS, Uganda4 org
7730 t Tropical medicine & international healthd : Wileyg 7:12, s. 1053-1063q 7:12<1053-1063x 1360-2276x 1365-3156
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-52351
8564 8u https://doi.org/10.1046/j.1365-3156.2002.00963.x

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