WFRF:(Kostromina Elena)
Sökning: WFRF:(Kostromina Elena) > Spatial and quantit...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03300naa a2200373 4500 | |
| 001 | oai:DiVA.org:umu-133764 | |
| 003 | SwePub | |
| 008 | 170503s2017 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1337642 URI |
| 024 | 7 | a https://doi.org/10.1038/sdata.2017.312 DOI |
| 040 | a (SwePub)umu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Parween, Sabau Umeå universitet,Umeå centrum för molekylär medicin (UCMM)4 aut0 (Swepub:umu)sapa0047 |
| 245 | 1 0 | a Spatial and quantitative datasets of the pancreatic beta-cell mass distribution in lean and obese mice |
| 264 | c 2017-03-14 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2017 |
| 338 | a electronic2 rdacarrier | |
| 520 | a A detailed understanding of pancreatic β-cell mass distribution is a key element to fully appreciate the pathophysiology of models of diabetes and metabolic stress. Commonly, such assessments have been performed by stereological approaches that rely on the extrapolation of two-dimensional data and provide very limited topological information. We present ex vivo optical tomographic data sets of the full β-cell mass distribution in cohorts of obese ob/ob mice and their lean controls, together with information about individual islet β-cell volumes, their three-dimensional coordinates and shape throughout the volume of the pancreas between 4 and 52 weeks of age. These data sets offer the currently most comprehensive public record of the β-cell mass distribution in the mouse. As such, they may serve as a quantitative and topological reference for the planning of a variety of in vivo or ex vivo experiments including computational modelling and statistical analyses. By shedding light on intra- and inter-lobular variations in β-cell mass distribution, they further provide a powerful tool for the planning of stereological sampling assessments. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinsk bioteknologix Biomedicinsk laboratorievetenskap/teknologi0 (SwePub)304022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Medical Biotechnologyx Biomedical Laboratory Science/Technology0 (SwePub)304022 hsv//eng |
| 700 | 1 | a Eriksson, Mariau Umeå universitet,Umeå centrum för molekylär medicin (UCMM)4 aut0 (Swepub:umu)maer0057 |
| 700 | 1 | a Nord, Christofferu Umeå universitet,Umeå centrum för molekylär medicin (UCMM)4 aut0 (Swepub:umu)chsv0004 |
| 700 | 1 | a Kostromina, Elenau Umeå universitet,Umeå centrum för molekylär medicin (UCMM)4 aut0 (Swepub:umu)elko0010 |
| 700 | 1 | a Ahlgren, Ulfu Umeå universitet,Umeå centrum för molekylär medicin (UCMM)4 aut0 (Swepub:umu)ulah0001 |
| 710 | 2 | a Umeå universitetb Umeå centrum för molekylär medicin (UCMM)4 org |
| 773 | 0 | t Scientific Datad : Springer Science and Business Media LLCg 4q 4x 2052-4463 |
| 856 | 4 | u https://doi.org/10.1038/sdata.2017.31y Fulltext |
| 856 | 4 | u https://umu.diva-portal.org/smash/get/diva2:1092488/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://www.nature.com/articles/sdata201731.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-133764 |
| 856 | 4 8 | u https://doi.org/10.1038/sdata.2017.31 |
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