Sökning: WFRF:(Laas J. C.) > (2020-2024) > Predictors of DAPSA...
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000 | 06811naa a2200949 4500 | |
001 | oai:gup.ub.gu.se/331555 | |
003 | SwePub | |
008 | 240528s2024 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:153447658 | |
009 | oai:lup.lub.lu.se:fbf3b100-aed3-4594-9218-1d6a0fcff35e | |
024 | 7 | a https://gup.ub.gu.se/publication/3315552 URI |
024 | 7 | a https://doi.org/10.1093/rheumatology/kead2842 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1534476582 URI |
024 | 7 | a https://lup.lub.lu.se/record/fbf3b100-aed3-4594-9218-1d6a0fcff35e2 URI |
040 | a (SwePub)gud (SwePub)kid (SwePub)lu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Linde, L.u Copenhagen University Hospital,University of Copenhagen4 aut |
245 | 1 0 | a Predictors of DAPSA28 remission in patients with psoriatic arthritis initiating a first TNF inhibitor: results from 13 European registries |
264 | 1 | c 2024 |
520 | a Objectives In bio-naive patients with PsA initiating a TNF inhibitor (TNFi), we aimed to identify baseline predictors of Disease Activity index for PsA in 28 joints (DAPSA28) remission (primary objective) and DAPSA28 moderate response at 6 months, as well as drug retention at 12 months across 13 European registries. Methods Baseline demographic and clinical characteristics were retrieved and the three outcomes investigated per registry and in pooled data, using logistic regression analyses on multiply imputed data. In the pooled cohort, selected predictors that were either consistently positive or negative across all three outcomes were defined as common predictors. Results In the pooled cohort (n = 13 369), 6-month proportions of remission, moderate response and 12-month drug retention were 25%, 34% and 63% in patients with available data (n = 6954, n = 5275 and n = 13 369, respectively). Five common baseline predictors of remission, moderate response and 12-month drug retention were identified across all three outcomes. The odds ratios (95% CIs) for DAPSA28 remission were: age, per year: 0.97 (0.96-0.98); disease duration, years (<2 years as reference): 2-3 years: 1.20 (0.89-1.60), 4-9 years: 1.42 (1.09-1.84), & GE;10 years: 1.66 (1.26-2.20); men vs women: 1.85 (1.54-2.23); CRP of >10 vs & LE;10 mg/l: 1.52 (1.22-1.89) and 1 mm increase in patient fatigue score: 0.99 (0.98-0.99). Conclusion Baseline predictors of remission, response and adherence to TNFi therapy were identified, of which five were common for all three outcomes, indicating that the predictors emerging from our pooled cohort may be considered generalizable from country level to disease level. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng |
653 | a PsA | |
653 | a first TNF-inhibitor | |
653 | a predictors | |
653 | a DAPSA28 | |
653 | a drug retention | |
653 | a real-world evidence | |
653 | a health-assessment questionnaire | |
653 | a rheumatoid-arthritis | |
653 | a clinical-response | |
653 | a drug survival | |
653 | a alpha therapy | |
653 | a spondyloarthritis | |
653 | a recommendations | |
653 | a efficacy | |
653 | a outcomes | |
653 | a rates | |
653 | a Rheumatology | |
700 | 1 | a Ornbjerg, L. M.u Copenhagen University Hospital4 aut |
700 | 1 | a Georgiadis, S.u Copenhagen University Hospital4 aut |
700 | 1 | a Rasmussen, S. H.4 aut |
700 | 1 | a Lindström, Ulfu University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research,Sahlgrenska Academy4 aut0 (Swepub:gu)xlulfn |
700 | 1 | a Askling, J.u Karolinska Institute,Karolinska Institutet4 aut |
700 | 1 | a Michelsen, B.u Diakonhjemmet Hospital,Sørlandet Hospital4 aut |
700 | 1 | a Di Giuseppe, D.u Karolinska Institute,Karolinska Institutet4 aut |
700 | 1 | a Wallman, Johan K.u Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Lund Arthritis Research Group (LARG),Forskargrupper vid Lunds universitet,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-jnk |
700 | 1 | a Gudbjornsson, B.u National University Hospital of Iceland4 aut |
700 | 1 | a Love, T. J.u National University Hospital of Iceland4 aut |
700 | 1 | a Nordstrom, D. C.u Helsinki University Central Hospital,Carol Davila University of Medicine and Pharmacy4 aut |
700 | 1 | a Yli-Kerttula, T.u Satakunta Central Hospital4 aut |
700 | 1 | a Nekvindova, L.u Charles University in Prague,Institute of Rheumatology, Prague4 aut |
700 | 1 | a Vencovsky, J.u Charles University in Prague,Institute of Rheumatology, Prague4 aut |
700 | 1 | a Iannone, F.u University of Bari Aldo Moro4 aut |
700 | 1 | a Cauli, A.u University of Cagliari4 aut |
700 | 1 | a Loft, A. G.u Aarhus University Hospital,Aarhus University4 aut |
700 | 1 | a Glintborg, B.u University of Copenhagen,Copenhagen University Hospital4 aut |
700 | 1 | a Laas, K.4 aut |
700 | 1 | a Rotar, Z.u University of Ljubljana,University Medical Centre Ljubljana4 aut |
700 | 1 | a Tomsic, M.u University Medical Centre Ljubljana,University of Ljubljana4 aut |
700 | 1 | a Macfarlane, G. J.4 aut |
700 | 1 | a Moller, B.u Bern University Hospital4 aut |
700 | 1 | a van de Sande, M.u University of Amsterdam4 aut |
700 | 1 | a Codreanu, C.4 aut |
700 | 1 | a Nissen, M. J.u Geneva University Hospital4 aut |
700 | 1 | a Birlik, M.u Dokuz Eylül University4 aut |
700 | 1 | a Erten, S.4 aut |
700 | 1 | a Santos, M. J.u Hospital Garcia de Orta4 aut |
700 | 1 | a Vieira-Sousa, E.u University of Lisbon4 aut |
700 | 1 | a Hetland, M. L.4 aut |
700 | 1 | a Ostergaard, M.u University of Copenhagen4 aut |
710 | 2 | a Copenhagen University Hospitalb University of Copenhagen4 org |
773 | 0 | t Rheumatologyg 63:3, s. 751-764q 63:3<751-764x 1462-0324 |
773 | 0 | t Rheumatology (Oxford, England)g 63:3, s. 751-764q 63:3<751-764x 1462-0332 |
856 | 4 | u http://dx.doi.org/10.1093/rheumatology/kead284x freey FULLTEXT |
856 | 4 8 | u https://gup.ub.gu.se/publication/331555 |
856 | 4 8 | u https://doi.org/10.1093/rheumatology/kead284 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:153447658 |
856 | 4 8 | u https://lup.lub.lu.se/record/fbf3b100-aed3-4594-9218-1d6a0fcff35e |
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