Sökning: WFRF:(Makedonsky Igor) > Bowel function and ...
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000 | 05502naa a2200625 4500 | |
001 | oai:lup.lub.lu.se:4e08332a-ed0d-4671-9b12-139c549b9f65 | |
003 | SwePub | |
008 | 220608s2022 | |||||||||||000 ||eng| | |
024 | 7 | a https://lup.lub.lu.se/record/4e08332a-ed0d-4671-9b12-139c549b9f652 URI |
024 | 7 | a https://doi.org/10.1016/j.jpedsurg.2022.02.0152 DOI |
040 | a (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a van der Steeg, Hendrik J.J.u Radboud University Medical Center4 aut |
245 | 1 0 | a Bowel function and associated risk factors at preschool and early childhood age in children with anorectal malformation type rectovestibular fistula : An ARM-Net consortium study |
264 | 1 | b Elsevier BV,c 2022 |
520 | a Background: Outcome of patients operated for anorectal malformation (ARM) type rectovestibular fistula (RVF) is generally considered to be good. However, large multi-center studies are scarce, mostly describing pooled outcome of different ARM-types, in adult patients. Therefore, counseling parents concerning the bowel function at early age is challenging. Aim of this study was to evaluate bowel function of RVF-patients at preschool/early childhood age and determine risk factors for poor functional outcome. Methods: A multi-center cohort study was performed. Patient characteristics, associated anomalies, sacral ratio, surgical procedures, post-reconstructive complications, one-year constipation, and Bowel Function Score (BFS) at 4–7 years of follow-up were registered. Groups with below normal (BFS < 17; subgroups ‘poor’ ≤ 11, and ‘fair’ 11 < BFS < 17) and good outcome (BFS ≥ 17) were formed. Univariable analyses were performed to detect risk factors for outcome. Results: The study included 111 RVF-patients. Median BFS was 16 (range 6–20). The ‘below normal’ group consisted of 61 patients (55.0%). Overall, we reported soiling, fecal accidents, and constipation in 64.9%, 35.1% and 70.3%, respectively. Bowel management was performed in 23.4% of patients. Risk factors for poor outcome were tethered cord and low sacral ratio, while sacral anomalies, low sacral ratio, prior enterostomy, post-reconstructive complications, and one-year constipation were for being on bowel management. Conclusions: Although median BFS at 4–7 year follow-up is nearly normal, the majority of patients suffers from some degree of soiling and constipation, and almost 25% needs bowel management. Several factors were associated with poor bowel function outcome and bowel management. Level of Evidence: Level III. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng |
653 | a Anorectal malformation | |
653 | a ARM-Net | |
653 | a Bowel function score | |
653 | a Early childhood | |
653 | a Observational cohort-study | |
653 | a Preschool age | |
653 | a Rectovestibular fistula | |
653 | a Type of study | |
700 | 1 | a van Rooij, Iris A.L.M.u Radboud University Medical Center4 aut |
700 | 1 | a Iacobelli, Barbara D.u Bambino Gesù Children’s Hospital4 aut |
700 | 1 | a Sloots, Cornelius E.J.u Sophia Children's Hospital4 aut |
700 | 1 | a Morandi, Annau Maggiore Hospital Policlinico4 aut |
700 | 1 | a Broens, Paul M.A.u University Medical Center Groningen4 aut |
700 | 1 | a Makedonsky, Igoru Children's Hospital Dnepropetrovsk4 aut |
700 | 1 | a Leon, Francesco Fascettiu University of Padova4 aut |
700 | 1 | a Schmiedeke, Eberhardu Klinikum Bremen-Mitte4 aut |
700 | 1 | a Vázquez, Araceli Garcíau 12 de Octubre University Hospital4 aut |
700 | 1 | a Miserez, Marcu Catholic University of Leuven4 aut |
700 | 1 | a Lisi, Gabrieleu University G.d'Annunzio of Chieti-Pescara4 aut |
700 | 1 | a Midrio, Paolau Treviso Hospital4 aut |
700 | 1 | a Amerstorfer, Eva E.u Medical University of Graz4 aut |
700 | 1 | a Fanjul, Mariau Hospital Gregorio Maranon4 aut |
700 | 1 | a Ludwiczek, Johannau Kepler University Hospital Linz4 aut |
700 | 1 | a Stenström, Pernillau Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Barnkirurgi,Forskargrupper vid Lunds universitet,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Pediatric surgery,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-pes |
700 | 1 | a van der Steeg, Alida F.W.u Academic Medical Center of University of Amsterdam (AMC),Princess Maxima Center for Pediatric Oncology/Hematology4 aut |
700 | 1 | a de Blaauw, Ivou Radboud University Medical Center4 aut |
710 | 2 | a Radboud University Medical Centerb Bambino Gesù Children’s Hospital4 org |
710 | 2 | a On behalf of the ARM-Net Consortium |
773 | 0 | t Journal of Pediatric Surgeryd : Elsevier BVg 57:9, s. 89-96q 57:9<89-96x 0022-3468 |
856 | 4 | u http://dx.doi.org/10.1016/j.jpedsurg.2022.02.015x freey FULLTEXT |
856 | 4 8 | u https://lup.lub.lu.se/record/4e08332a-ed0d-4671-9b12-139c549b9f65 |
856 | 4 8 | u https://doi.org/10.1016/j.jpedsurg.2022.02.015 |
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