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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005701naa a2200673 4500
001oai:DiVA.org:liu-188157
003SwePub
008220907s2022 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1881572 URI
0247 a https://doi.org/10.1016/j.bja.2022.03.0262 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Fronczek, Jakubu Jagiellonian Univ Med Coll, Poland4 aut
2451 0a Short-term mortality or patients >= 80 years old admitted to European intensive care units: an international observational study
264 1b ELSEVIER SCI LTD,c 2022
338 a print2 rdacarrier
500 a Funding Agencies|Polish National Agency for Academic Exchange, Iwanowska Programme [PPN/IWA/2019/1/00106]; Polpharma Scientific Foundation
520 a Background: Limited evidence suggests variation in mortality of older critically ill adults across Europe. We aimed to investigate regional differences in mortality among very old ICU patients. Methods: Multilevel analysis of two international prospective cohort studies. We included patients >= 80 yr old from 322 ICUs located in 16 European countries. The primary outcome was mortality within 30 days from admission to the ICU. Results are presented as n (%) with 95% confidence intervals and odds ratios (ORs). Results: Of 8457 patients, 2944 (36.9% [35.9-38.0%]) died within 30 days. Crude mortality rates varied widely between participating countries (from 10.1% [6.4-15.6%] to 45.1% [41.1-49.2%] in the ICU and from 21.3% [16.3-28.9%] to 55.3% [51.1-59.5%] within 30 days). After adjustment for confounding variables, the variation in 30-day mortality between countries was substantially smaller than between ICUs (median OR 1.14 vs 1.58). Healthcare expenditure per capita (OR=0.84 per $1000 [0.75-0.94]) and social health insurance framework (OR=1.43 [1.01-2.01]) were associated with ICU mortality, but the direction and magnitude of these relationships was uncertain in 30-day follow-up. Volume of admissions was associated with lower mortality both in the ICU (OR=0.81 per 1000 annual ICU admissions [0.71-0.94]) and in 30-day follow-up (OR=0.86 [0.76-0.97]). Conclusion: The apparent variation in short-term mortality rates of older adults hospitalised in ICUs across Europe can be largely attributed to differences in the clinical profile of patients admitted. The volume-outcome relationship identified in this population requires further investigation.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Anestesi och intensivvård0 (SwePub)302012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Anesthesiology and Intensive Care0 (SwePub)302012 hsv//eng
653 a cohort studies; critical care outcomes; critical illness; Europe; intensive care unit; mortality; old patients; outcome assessment; variation
7001 a Flaatten, Hansu Haukeland Hosp, Norway; Univ Bergen, Norway4 aut
7001 a Guidet, Bertrandu UPMC Univ Paris 06, France; Hop St Antoine, France4 aut
7001 a Polok, Kamilu Jagiellonian Univ Med Coll, Poland4 aut
7001 a Andersen, Finn H.u Alesund Hosp, Norway; NTNU, Norway4 aut
7001 a Andrew, Benjamin Y.u Duke Univ, NC 27710 USA4 aut
7001 a Artigas, Antoniou Autonomous Univ Barcelona, Spain4 aut
7001 a Beil, Michaelu Hadassah Med Ctr, Israel4 aut
7001 a Cecconi, Mauriziou Humanitas Clin & Res Ctr IRCCS, Italy; Humanitas Univ, Italy4 aut
7001 a Christensen, Steffenu Aarhus Univ Hosp, Denmark4 aut
7001 a de Lange, Dylan W.u Univ Utrecht, Netherlands4 aut
7001 a Fjolner, Jesperu Aarhus Univ Hosp, Denmark4 aut
7001 a Gorka, Jaceku Jagiellonian Univ Med Coll, Poland4 aut
7001 a Joannidis, Michaelu Med Univ Innsbruck, Austria4 aut
7001 a Jung, Christianu Heinrich Heine Univ, Germany4 aut
7001 a Kusza, Krzysztofu Poznan Univ Med Sci, Poland4 aut
7001 a Leaver, Susannahu St George Hosp, England4 aut
7001 a Marsh, Brianu Mater Misericordiae Univ Hosp, Ireland4 aut
7001 a Morandi, Alessandrou Geriatr Res Grp, Italy4 aut
7001 a Moreno, Ruiu Ctr Hosp Univ Lisboa Cent, Portugal4 aut
7001 a Oeyen, Sandrau Ghent Univ Hosp, Belgium4 aut
7001 a Owczuk, Radoslawu Med Univ Gdansk, Poland4 aut
7001 a Agvald-Ohman, Christinau Karolinska Univ Hosp, Sweden4 aut
7001 a Pinto, Bernardo B.u Geneva Univ Hosp, Switzerland4 aut
7001 a Rhodes, Andrewu St Georges Univ Hosp NHS Fdn Trust, England4 aut
7001 a Schefold, Joerg C.u Univ Bern, Switzerland4 aut
7001 a Soliman, Ivo W.u Univ Utrecht, Netherlands4 aut
7001 a Valentin, Andreasu Kardinal Schwarzenberg Hosp, Austria4 aut
7001 a Walther, Stenu Linköpings universitet,Medicinska fakulteten,Institutionen för hälsa, medicin och vård,Region Östergötland, Thorax-kärlkliniken i Östergötland,Region Östergötland, ANOPIVA US4 aut0 (Swepub:liu)stewa50
7001 a Watson, Ximenau St Georges Univ Hosp NHS Fdn Trust, England4 aut
7001 a Zafeiridis, Tilemachosu Gen Hosp Larissa, Greece4 aut
7001 a Szczeklik, Wojciechu Jagiellonian Univ Med Coll, Poland4 aut
7102 a Jagiellonian Univ Med Coll, Polandb Haukeland Hosp, Norway; Univ Bergen, Norway4 org
7730 t British Journal of Anaesthesiad : ELSEVIER SCI LTDg 129:1, s. 58-66q 129:1<58-66x 0007-0912x 1471-6771
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-188157
8564 8u https://doi.org/10.1016/j.bja.2022.03.026

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