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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003398naa a2200553 4500
001oai:gup.ub.gu.se/323587
003SwePub
008240528s2022 | |||||||||||000 ||eng|
024a https://gup.ub.gu.se/publication/3235872 URI
024a https://doi.org/10.3390/v141124652 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Manuylov, V.4 aut
2451 0a Genetic Diversity and Possible Origins of the Hepatitis B Virus in Siberian Natives
264 c 2022-11-07
264 1b MDPI AG,c 2022
520 a A total of 381 hepatitis B virus (HBV) DNA sequences collected from nine groups of Siberian native populations were phylogenetically analyzed along with 179 HBV strains sampled in different urban populations of former western USSR republics and 50 strains from Central Asian republics and Mongolia. Different HBV subgenotypes predominated in various native Siberian populations. Subgenotype D1 was dominant in Altaian Kazakhs (100%), Tuvans (100%), and Teleuts (100%) of southern Siberia as well as in Dolgans and Nganasans (69%), who inhabit the polar Taimyr Peninsula. D2 was the most prevalent subgenotype in the combined group of Nenets, Komi, and Khants of the northern Yamalo-Nenets Autonomous Region (71%) and in Yakuts (36%) from northeastern Siberia. D3 was the main subgenotype in South Altaians (76%) and Buryats (40%) of southeastern Siberia, and in Chukchi (51%) of the Russian Far East. Subgenotype C2 was found in Taimyr (19%) and Chukchi (27%), while subgenotype A2 was common in Yakuts (33%). In contrast, D2 was dominant (56%) in urban populations of the former western USSR, and D1 (62%) in Central Asian republics and Mongolia. Statistical analysis demonstrated that the studied groups are epidemiologically isolated from each other and might have contracted HBV from different sources during the settlement of Siberia.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng
653 a aboriginal population
653 a genotypes
653 a HBsAg subtypes
653 a hepatitis B virus
653 a molecular epidemiology
653 a Siberia
653 a Siberian natives
653 a subgenotypes
700a Chulanov, V.4 aut
700a Bezuglova, L.4 aut
700a Chub, E.4 aut
700a Karlsen, A.4 aut
700a Kyuregyan, K.4 aut
700a Ostankova, Y.4 aut
700a Semenov, A.4 aut
700a Osipova, L.4 aut
700a Tallo, T.4 aut
700a Netesova, I.4 aut
700a Tkachuk, A.4 aut
700a Gushchin, V.4 aut
700a Netesov, S.4 aut
700a Magnius, L. O.4 aut
700a Norder, Heleneu Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine4 aut0 (Swepub:gu)xnordh
710a Göteborgs universitetb Institutionen för biomedicin, avdelningen för infektionssjukdomar4 org
773t Virusesd : MDPI AGg 14:11q 14:11x 1999-4915
8564 8u https://gup.ub.gu.se/publication/323587
8564 8u https://doi.org/10.3390/v14112465

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