Sökning: WFRF:(Wrigge H) > The effects of preo...
Fältnamn | Indikatorer | Metadata |
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000 | 04452naa a2200565 4500 | |
001 | oai:DiVA.org:uu-435884 | |
003 | SwePub | |
008 | 210301s2021 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4358842 URI |
024 | 7 | a https://doi.org/10.1097/EJA.00000000000014122 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Bulte, Carolien S. E.4 aut |
245 | 1 0 | a The effects of preoperative moderate to severe anaemia on length of hospital stay :b A propensity score-matched analysis in non-cardiac surgery patients |
264 | 1 | b Wolters Kluwer,c 2021 |
338 | a print2 rdacarrier | |
520 | a BACKGROUND Anaemia is frequently recorded during preoperative screening and has been suggested to affect outcomes after surgery negatively.OBJECTIVES The objectives were to assess the frequency of moderate to severe anaemia and its association with length of hospital stay.DESIGN Post hoc analysis of the international observational prospective ‘Local ASsessment of VEntilatory management during General Anaesthesia for Surgery’ (LAS VEGAS) study.PATIENTS AND SETTING The current analysis included adult patients requiring general anaesthesia for non-cardiac surgery. Preoperative anaemia was defined as a haemoglobin concentration of 11 g dl−1 or lower, thus including moderate and severe anaemia according to World Health Organisation criteria.MAIN OUTCOME MEASURES The primary outcome was length of hospital stay. Secondary outcomes included hospital mortality, intra-operative adverse events and postoperative pulmonary complications (PPCs).RESULTS Haemoglobin concentrations were available for 8264 of 9864 patients. Preoperative moderate to severe anaemia was present in 7.7% of patients. Multivariable analysis showed that preoperative moderate to severe anaemia was associated with an increased length of hospital stay with a mean difference of 1.3 ((95% CI 0.8 to 1.8) days; P < .001). In the propensity-matched analysis, this association remained present, median 4.0 [IQR 1.0 to 5.0] vs. 2.0 [IQR 0.0 to 5.0] days, P = .001. Multivariable analysis showed an increased in-hospital mortality (OR 2.9 (95% CI 1.1 to 7.5); P = .029), and higher incidences of intra-operative hypotension (36.3 vs. 25.3%; P < .001) and PPCs (17.1 vs. 10.5%; P = .001) in moderately to severely anaemic patients. However, this was not confirmed in the propensity score-matched analysis.CONCLUSIONS In this international cohort of non-cardiac surgical patients, preoperative moderate to severe anaemia was associated with a longer duration of hospital stay but not increased intra-operative complications, PPCs or in-hospital mortality. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Anestesi och intensivvård0 (SwePub)302012 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Anesthesiology and Intensive Care0 (SwePub)302012 hsv//eng |
653 | a Physiology | |
653 | a Fysiologi | |
653 | a Anaesthesiology and Intensive Care | |
653 | a Anestesiologi och intensivvård | |
700 | 1 | a Boer, Christa4 aut |
700 | 1 | a Hemmes, Sabrine N. T.4 aut |
700 | 1 | a Serpa Neto, Ary4 aut |
700 | 1 | a Binnekade, Jan M.4 aut |
700 | 1 | a Hedenstierna, Göran,d 1941-u Uppsala universitet,Hedenstiernalaboratoriet4 aut0 (Swepub:uu)goranhed |
700 | 1 | a Jaber, Samir4 aut |
700 | 1 | a Hiesmayr, Michael4 aut |
700 | 1 | a Hollmann, Markus W.4 aut |
700 | 1 | a Mills, Gary H.4 aut |
700 | 1 | a Vidal Melo, Marcos F.4 aut |
700 | 1 | a Pearse, Rupert M.4 aut |
700 | 1 | a Putensen, Christian4 aut |
700 | 1 | a Schmid, Werner4 aut |
700 | 1 | a Severgnini, Paolo4 aut |
700 | 1 | a Wrigge, Hermann4 aut |
700 | 1 | a Gama de Abreu, Marcelo4 aut |
700 | 1 | a Pelosi, Paolo4 aut |
700 | 1 | a Schultz, Marcus J.4 aut |
710 | 2 | a Uppsala universitetb Hedenstiernalaboratoriet4 org |
773 | 0 | t European Journal of Anaesthesiologyd : Wolters Kluwerg 38:6, s. 571-581q 38:6<571-581x 0265-0215x 1365-2346 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-435884 |
856 | 4 8 | u https://doi.org/10.1097/EJA.0000000000001412 |
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