Near infrared radiation damage mechanism in the lens

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Fältnamn	Indikatorer	Metadata
000		02745naa a2200397 4500
001		oai:DiVA.org:uu-257175
003		SwePub
008		150630s2015 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2571752 URI
024	7	a https://doi.org/10.1117/12.20866612 DOI
040		a (SwePub)uu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a kon2 swepub-publicationtype
100	1	a Söderberg, Per G.u Uppsala universitet,Oftalmiatrik4 aut0 (Swepub:uu)perso438
245	1 0	a Near infrared radiation damage mechanism in the lens
264	1	b SPIE,c 2015
338		a print2 rdacarrier
520		a The current data strongly indicates that there is no photochemical effect of in vivo exposure to 1090 nm near IRR radiation within the pupil. Four groups of 20 Sprague-Dawley rats were unilaterally exposed in vivo to 96 W.cm(-2) centered inside the pupil for 10, 18, 33 and 60 min, respectively depending on group belonging. This resulted in radiant exposure doses of 57, 103, 198 and 344 kJ.cm(-2). Temperature evolution at the limbus during the exposure and difference of intensity of forward light scattering between the exposed and the contralateral not exposed eye was measured at 1 week after exposure. The temperature at the limbus was found to increase exponentially towards an asymptote with an asymptote temperature of around 7 degrees C and a time constant (1/k) of around 15 s. No increase of light scattering was found despite that the cumulated radiant exposure dose was [80; 250] times the threshold for photochemically induced cataract suggested by previous empirical data. It is concluded that at 1090 nm near IRR there is no photochemical effect.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Oftalmologi0 (SwePub)302172 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Ophthalmology0 (SwePub)302172 hsv//eng
653		a near infrared radiation
653		a cataract
653		a in vivo
653		a photochemical
653		a thermal
700	1	a Talebizadeh, Nooshinu Uppsala universitet,Oftalmiatrik4 aut0 (Swepub:uu)noota977
700	1	a Galichanin, Konstantinu Uppsala universitet,Oftalmiatrik4 aut0 (Swepub:uu)konga695
700	1	a Kronschläger, Martinu Uppsala universitet,Oftalmiatrik4 aut0 (Swepub:uu)markr689
700	1	a Schulmeister, Karl4 aut
700	1	a Yu, Zhaohuau Uppsala universitet,Oftalmiatrik4 aut0 (Swepub:uu)zhayu760
710	2	a Uppsala universitetb Oftalmiatrik4 org
773	0	t OPHTHALMIC TECHNOLOGIES XXVd : SPIEz 9781628413977
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-257175
856	4 8	u https://doi.org/10.1117/12.2086661

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Av författaren/redakt...: Söderberg, Per G ...; Talebizadeh, Noo ...; Galichanin, Kons ...; Kronschläger, Ma ...; Schulmeister, Ka ...; Yu, Zhaohua

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