Sökning: WFRF:(Zabzuni D.) > Safety of Anticoagu...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 06825naa a2201417 4500 | |
001 | oai:gup.ub.gu.se/297398 | |
003 | SwePub | |
008 | 240528s2020 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/2973982 URI |
024 | 7 | a https://doi.org/10.1161/STROKEAHA.120.0301432 DOI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Giustozzi, M.4 aut |
245 | 1 0 | a Safety of Anticoagulation in Patients Treated with Urgent Reperfusion for Ischemic Stroke Related to Atrial Fibrillation |
264 | 1 | c 2020 |
520 | a Background and Purpose: The optimal timing for starting oral anticoagulant after an ischemic stroke related to atrial fibrillation remains a challenge, mainly in patients treated with systemic thrombolysis or mechanical thrombectomy. We aimed at assessing the incidence of early recurrence and major bleeding in patients with acute ischemic stroke and atrial fibrillation treated with thrombolytic therapy and/or thrombectomy, who then received oral anticoagulants for secondary prevention. Methods: We combined the dataset of the RAF and the RAF-NOACs (Early Recurrence and Major Bleeding in Patients With Acute Ischemic Stroke and Atrial Fibrillation Treated With Non-Vitamin K Oral Anticoagulants) studies, which were prospective observational studies carried out from January 2012 to March 2014 and April 2014 to June 2016, respectively. We included consecutive patients with acute ischemic stroke and atrial fibrillation treated with either vitamin K antagonists or nonvitamin K oral anticoagulants. Primary outcome was the composite of stroke, transient ischemic attack, symptomatic systemic embolism, symptomatic cerebral bleeding, and major extracerebral bleeding within 90 days from the inclusion. Treated-patients were propensity matched to untreated-patients in a 1:1 ratio after stratification by baseline clinical features. Results: A total of 2159 patients were included, 564 (26%) patients received acute reperfusion therapies. After the index event, 505 (90%) patients treated with acute reperfusion therapies and 1287 of 1595 (81%) patients untreated started oral anticoagulation. Timing of starting oral anticoagulant was similar in reperfusion-treated and untreated patients (median 7.5 versus 7.0 days, respectively). At 90 days, the primary study outcome occurred in 37 (7%) patients treated with reperfusion and in 146 (9%) untreated patients (odds ratio, 0.74 [95% CI, 0.50-1.07]). After propensity score matching, risk of primary outcome was comparable between the 2 groups (odds ratio, 1.06 [95% CI, 0.53-2.02]). Conclusions: Acute reperfusion treatment did not influence the risk of early recurrence and major bleeding in patients with atrial fibrillation-related acute ischemic stroke, who started on oral anticoagulant. © 2020 Georg Thieme Verlag. All rights reserved. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
653 | a anticoagulants | |
653 | a atrial fibrillation | |
653 | a secondary prevention | |
653 | a thrombectomy | |
653 | a thrombolytic therapy | |
700 | 1 | a Acciarresi, M.4 aut |
700 | 1 | a Agnelli, G.4 aut |
700 | 1 | a Caso, V.4 aut |
700 | 1 | a Bandini, F.4 aut |
700 | 1 | a Tsivgoulis, G.4 aut |
700 | 1 | a Yaghi, S.4 aut |
700 | 1 | a Furie, K. L.4 aut |
700 | 1 | a Tadi, P.4 aut |
700 | 1 | a Becattini, C.4 aut |
700 | 1 | a Zedde, M.4 aut |
700 | 1 | a Abdul-Rahim, A. H.4 aut |
700 | 1 | a Lees, K. R.4 aut |
700 | 1 | a Alberti, A.4 aut |
700 | 1 | a Venti, M.4 aut |
700 | 1 | a D'Amore, C.4 aut |
700 | 1 | a Giulia Mosconi, M.4 aut |
700 | 1 | a Anna Cimini, L.4 aut |
700 | 1 | a Bovi, P.4 aut |
700 | 1 | a Carletti, M.4 aut |
700 | 1 | a Rigatelli, A.4 aut |
700 | 1 | a Cappellari, M.4 aut |
700 | 1 | a Putaala, J.4 aut |
700 | 1 | a Tomppo, L.4 aut |
700 | 1 | a Tatlisumak, Turgutu Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology4 aut0 (Swepub:gu)xtatlt |
700 | 1 | a Marcheselli, S.4 aut |
700 | 1 | a Pezzini, A.4 aut |
700 | 1 | a Poli, L.4 aut |
700 | 1 | a Padovani, A.4 aut |
700 | 1 | a Vannucchi, V.4 aut |
700 | 1 | a Sohn, S. I.4 aut |
700 | 1 | a Lorenzini, G.4 aut |
700 | 1 | a Tassi, R.4 aut |
700 | 1 | a Guideri, F.4 aut |
700 | 1 | a Acampa, M.4 aut |
700 | 1 | a Martini, G.4 aut |
700 | 1 | a Ntaios, G.4 aut |
700 | 1 | a Athanasakis, G.4 aut |
700 | 1 | a Makaritsis, K.4 aut |
700 | 1 | a Karagkiozi, E.4 aut |
700 | 1 | a Vadikolias, K.4 aut |
700 | 1 | a Liantinioti, C.4 aut |
700 | 1 | a Theodorou, A.4 aut |
700 | 1 | a Halvatsiotis, P.4 aut |
700 | 1 | a Mumoli, N.4 aut |
700 | 1 | a Galati, F.4 aut |
700 | 1 | a Sacco, S.4 aut |
700 | 1 | a Tiseo, C.4 aut |
700 | 1 | a Corea, F.4 aut |
700 | 1 | a Ageno, W.4 aut |
700 | 1 | a Bellesini, M.4 aut |
700 | 1 | a Silvestrelli, G.4 aut |
700 | 1 | a Ciccone, A.4 aut |
700 | 1 | a Lanari, A.4 aut |
700 | 1 | a Scoditti, U.4 aut |
700 | 1 | a Denti, L.4 aut |
700 | 1 | a Mancuso, M.4 aut |
700 | 1 | a Ferrari, E.4 aut |
700 | 1 | a Ulivi, L.4 aut |
700 | 1 | a Orlandi, G.4 aut |
700 | 1 | a Giannini, N.4 aut |
700 | 1 | a Tassinari, T.4 aut |
700 | 1 | a Luisa De Lodovici, M.4 aut |
700 | 1 | a Rueckert, C.4 aut |
700 | 1 | a Baldi, A.4 aut |
700 | 1 | a Toni, D.4 aut |
700 | 1 | a Letteri, F.4 aut |
700 | 1 | a Giuntini, M.4 aut |
700 | 1 | a Maria Lotti, E.4 aut |
700 | 1 | a Flomin, Y.4 aut |
700 | 1 | a Pieroni, A.4 aut |
700 | 1 | a Kargiotis, O.4 aut |
700 | 1 | a Karapanayiotides, T.4 aut |
700 | 1 | a Monaco, S.4 aut |
700 | 1 | a Maimone Baronello, M.4 aut |
700 | 1 | a Csiba, L.4 aut |
700 | 1 | a Szabó, L.4 aut |
700 | 1 | a Chiti, A.4 aut |
700 | 1 | a Giorli, E.4 aut |
700 | 1 | a Del Sette, M.4 aut |
700 | 1 | a Imberti, D.4 aut |
700 | 1 | a Zabzuni, D.4 aut |
700 | 1 | a Doronin, B.4 aut |
700 | 1 | a Volodina, V.4 aut |
700 | 1 | a Michel, P.4 aut |
700 | 1 | a Vanacker, P.4 aut |
700 | 1 | a Barlinn, K.4 aut |
700 | 1 | a Barlinn, J.4 aut |
700 | 1 | a Deleu, D.4 aut |
700 | 1 | a Gourbali, V.4 aut |
700 | 1 | a Paciaroni, M.4 aut |
700 | 1 | a Masotti, L.4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi4 org |
773 | 0 | t Strokeg 51:8, s. 2347-2354q 51:8<2347-2354x 0039-2499 |
856 | 4 8 | u https://gup.ub.gu.se/publication/297398 |
856 | 4 8 | u https://doi.org/10.1161/STROKEAHA.120.030143 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.