WFRF:(Zhu Zhenyu)
Search: WFRF:(Zhu Zhenyu) > (2020-2024) > Absorption and tran...
- 5 of 7
- Previous record
- Next record
- To hitlist
Absorption and transport of a Mytilus edulis-derived peptide with the function of preventing osteoporosis
-
- Xu, Zhe (author)
- Dalian Polytech Univ, Collaborat Innovat Ctr Seafood Deep Proc, Natl Engn Res Ctr Seafood, Sch Food Sci & Technol, Dalian 116034, Peoples R China.;Dalian Minzu Univ, Minist Educ, Coll Life Sci, Key Lab Biotechnol & Bioresources Utilizat, Dalian 116029, Peoples R China.
-
- Fan, Fengjiao (author)
- Nanjing Univ Finance & Econ, Coll Food Sci & Engn, Nanjing 210046, Peoples R China.
-
- Chen, Hui (author)
- Zhejiang Univ Technol, Coll Food Sci & Technol, Hangzhou 310014, Peoples R China.
- show more...
- show less...
- Dalian Polytech Univ, Collaborat Innovat Ctr Seafood Deep Proc, Natl Engn Res Ctr Seafood, Sch Food Sci & Technol, Dalian 116034, Peoples R China;Dalian Minzu Univ, Minist Educ, Coll Life Sci, Key Lab Biotechnol & Bioresources Utilizat, Dalian 116029, Peoples R China. Nanjing Univ Finance & Econ, Coll Food Sci & Engn, Nanjing 210046, Peoples R China. (creator_code:org_t)
- 2021
- 2021
- English.
- In: Food & Function. - : Royal Society of Chemistry. - 2042-6496 .- 2042-650X. ; 12:5, s. 2102-2111
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- The YPRKDETGAERT peptide (PME-1) identified from the Mytilus edulis proteins has been shown to promote the proliferation and differentiation of osteoblasts and it has good bone-forming activity in vitro. Further, PME-1 has been shown to prevent osteoporosis in vivo. PME-1 can be absorbed through the gastrointestinal tract, and the passing rate in monolayer Caco-2 cells was 6.57%. PME-1 can also enter the blood circulation and the concentration of PME-1 in serum reached the maximum, 61.06 +/- 26.32 ng mL(-1), 20 min after feeding. The multifunctional in vivo imager was used to further determine the distribution of the 5-FITC-(Acp)-YPRKDETGAERT peptide (PME-1-FITC) 2 h after feeding the peptide, and the result confirmed the above results and showed that a part of PME-1-FITC can affect bone in vivo. Therefore, PME-1 not only was easily absorbed in the gastrointestinal tract, but also has the potential beneficial effect on preventing osteoporosis.
Subject headings
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Food & Function (Search for host publication in LIBRIS)
To the university's database
- 5 of 7
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Xu, Zhe
- Fan, Fengjiao
- Chen, Hui
- Shi, Pujie
- Zhu, Dongyang
- Yang, Meilian
- show more...
- Wang, Zhenyu
- El-Seedi, Hesham
- Du, Ming
- show less...
- About the subject
-
- NATURAL SCIENCES
- NATURAL SCIENCES
- and Biological Scien ...
- and Biochemistry and ...
- Articles in the publication
- Food & Function
- By the university
- Uppsala University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
