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LifeGene - A large ...
LifeGene - A large prospective population-based study of global relevance
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- Almqvist, Catarina (författare)
- Karolinska Institutet
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- Adami, Hans-Olov (författare)
- Karolinska Institutet
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- Franks, Paul (författare)
- Umeå universitet,Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Medicin
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- Groop, Leif (författare)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
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- Ingelsson, Erik (författare)
- Karolinska Institutet
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- Kere, Juha (författare)
- Karolinska Institutet
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- Lissner, Lauren, 1956 (författare)
- Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
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- Litton, Jan-Eric (författare)
- Karolinska Institutet
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- Maeurer, Markus (författare)
- Karolinska Institutet
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- Michaëlsson, Karl, 1959- (författare)
- Uppsala universitet,Ortopedi
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- Palmgren, Juni (författare)
- Stockholms universitet,Karolinska Institutet,Matematiska institutionen
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- Pershagen, Göran (författare)
- Karolinska Institutet
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- Ploner, Alexander (författare)
- Karolinska Institutet
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Sullivan, Patrick F. (författare)
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- Tybring, Gunnel (författare)
- Karolinska Institutet
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Pedersen, Nancy L. (författare)
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(creator_code:org_t)
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- ISSN 1573-7284
- 2010-11-21
- 2011
- Engelska.
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Ingår i: European Journal of Epidemiology. - Stockholm : Springer Science and Business Media LLC. - 0393-2990 .- 1573-7284. ; 26:1, s. 67-77
- Relaterad länk:
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https://europepmc.or...
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http://dx.doi.org/10...
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http://hdl.handle.ne... (primary) (Object in context) (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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https://gup.ub.gu.se...
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http://hdl.handle.ne...
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https://urn.kb.se/re...
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http://kipublication...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Studying gene-environment interactions requires that the amount and quality of the lifestyle data is comparable to what is available for the corresponding genomic data. Sweden has several crucial prerequisites for comprehensive longitudinal biomedical research, such as the personal identity number, the universally available national health care system, continuously updated population and health registries and a scientifically motivated population. LifeGene builds on these strengths to bridge the gap between basic research and clinical applications with particular attention to populations, through a unique design in a research-friendly setting. LifeGene is designed both as a prospective cohort study and an infrastructure with repeated contacts of study participants approximately every 5 years. Index persons aged 18-45 years old will be recruited and invited to include their household members (partner and any children). A comprehensive questionnaire addressing cutting-edge research questions will be administered through the web with short follow-ups annually. Biosamples and physical measurements will also be collected at baseline, and re-administered every 5 years thereafter. Event-based sampling will be a key feature of LifeGene. The household-based design will give the opportunity to involve young couples prior to and during pregnancy, allowing for the first study of children born into cohort with complete pre-and perinatal data from both the mother and father. Questions and sampling schemes will be tailored to the participants' age and life events. The target of LifeGene is to enrol 500,000 Swedes and follow them longitudinally for at least 20 years.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Biobank
- Cohort study
- Epidemiology
- Population genetics
- Prospective study
- Questionnaires
- MEDICINE
- MEDICIN
- Biobank
- Cohort study
- Epidemiology
- Prospective study
- Questionnaires
- Population genetics
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Almqvist, Catari ...
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Adami, Hans-Olov
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Franks, Paul
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Groop, Leif
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Ingelsson, Erik
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Kere, Juha
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Lissner, Lauren, ...
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Litton, Jan-Eric
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Maeurer, Markus
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Michaëlsson, Kar ...
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Palmgren, Juni
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Pershagen, Göran
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Ploner, Alexande ...
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Sullivan, Patric ...
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Tybring, Gunnel
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Pedersen, Nancy ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Folkhälsovetensk ...
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European Journal ...
- Av lärosätet
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Uppsala universitet
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Lunds universitet
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Göteborgs universitet
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Karolinska Institutet
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Umeå universitet
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Stockholms universitet
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